Browsing by Author "Bitlisli, Behzat O."

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    Article
    Collagen-Based Hydrogel Films as Drug-Delivery Devices With Antimicrobial Properties
    (Springer, 2014) Sahiner, Mehtap; Alpaslan, Duygu; Bitlisli, Behzat O.
    Collagen (coll)-containing hydrogel films were prepared by mixing degraded collagen with monomers such as acrylamide (AAm), and 2-hydroxy ethylmethacrylate (HEMA) before the polymerization/cross-linking of composites as p(coll-co-AAm), and p(coll-co-HEMA), respectively. These materials were used as drug-delivery devices for potential wound dressing materials by loading and releasing of model drugs such as gallic acid (GA) and naproxen (NP). A linear release profile was obtained up to 32-h release from GA-loaded p(coll-co-AAm) interpenetrating polymeric networks films, and 36-h linear release profile of NP for p(coll-co-HEMA). Furthermore, metal nanoparticles such as Ag and Cu prepared within these hydrogel films offered antimicrobial characteristic against known common bacteria such as Escherichia coli, Bacillus subtilis, and Staphylococcus aureus.
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    Conference Object
    Hybrid Hydrogel Films With Antimicrobial Properties
    (Amer Chemical Soc, 2013) Sahiner, Mehtap; Alpaslan, Duygu; Bitlisli, Behzat O.