Browsing by Author "Celik, M."
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Article A Comparative Perspective on Brucellar, Pyogenic, and Tuberculous Spondylodiscitis(Verduci Editore s.r.l, 2024) Baran, A.I.; Celik, M.; Arslan, Y.; Incecik, S.; Binici, I.; Toprak, M.; Sunnetcioglu, M.OBJECTIVE: Non-specific features of spondylodiscitis lead to a delay and challenge in the diagnosis/differential diagnosis/treatment processes, and thus, serious complications may arise. This study aims to compare brucellar, pyogenic, and tuberculous types of spondylodiscitis, considering their demographic, clinical, and laboratory differences. This may provide more rapid management and good outcomes. PATIENTS AND METHODS: A total of 131 patients with infectious spondylodiscitis were included in the study. The patients were divided into brucellar (n=63), pyogenic (n=53), and tuberculous (n=15) types of spondylodiscitis and compared for demographic, clinical, laboratory, and imaging features. RESULTS: Tuberculous spondylodiscitis had higher scores for weight loss, painless palpation, thoracic spine involvement, and psoas abscess formation than other spondylodiscitis. Also, tuberculous spondylodiscitis had higher rates of neurologic deficit and lower rates of lumbar involvement than brucellar spondylodiscitis. Pyogenic spondylodiscitis is more likely to occur in patients who have a history of spine surgery compared to other forms of spondylodiscitis. Also, pyogenic spondylodiscitis had higher rates of fever, erythema, paraspinal abscess, white blood cell (WBC), and erythrocyte sedimentation rate (ESR) than brucellar spondylodiscitis. On the other hand, brucellar spondylodiscitis had higher rates of rural living and sweating than pyogenic spondylodiscitis. CONCLUSIONS: Weight loss, painless palpation, involved thoracic spine, psoas abscess, and neurologic deficit are symptoms favoring tuberculous spondylodiscitis. History of spine surgery, high fever, skin erythema, and paraspinal abscess are findings in favor of pyogenic spondylodiscitis. Rural living, sweating, and involved lumbar spine are symptoms that indicate brucellar spondylodiscitis. These symptoms can be used to distinguish the types of spondylodiscitis. © 2024 Verduci Editore s.r.l. All rights reserved.Article Comparison of Carbapenem Resistance Detected by the Bd Phoenix Automated System in Enterobacteriaceae Isolates With E-Test Method(Modestum LTD, 2022) Celik, M.; Sunnetcioglu, M.; Guducuoglu, H.; Arslan, Y.; Akyuz, S.; Baran, A.I.Objective: Automatic identification and antimicrobial susceptibility systems are frequently used to identify clinical isolates in hospitalized patients, but mistakes in these systems can lead to potentially devastating treatment failures for patients. Therefore, the ‘‘Centers for Disease Control and Prevention (CDC)’’ recommends confirming all Carbapenem-resistant and low-susceptibility isolates with a different method. The aim of this study is to compare the Carbapenem susceptibility results of isolates reported as Carbapenem-resistant Enterobacteriaceae according to the BD Phoenix 100 automated system with the E-test method. Materials and Methods: The study included 70 strains of Carbapenem-resistant Enterobacteriaceae members which were isolated and grown from several types of clinical samples in the Medical Microbiology Laboratory. Conventional methods (Gram stain, negative oxidase test) and the BD Phoenix 100 automated system were used to identify the isolates. The susceptibility of all strains to imipenem, ertapenem and meropenem was investigated by E-test method. Automated system results and E-test results were compared. Results: The frequency distribution of all isolated bacterial strains comprised K. pneumoniae in 56 (80%) of the samples included in the study. The automated system test results were correlated with the results of the E-test at a rate of 96.1 % for the imipenem-resistant strains, 84.3% for the meropenem-resistant strains, 84.1% for the ertapenem-resistant strains Conclusions: Automated systems are frequently used in microbiology laboratories to identify isolates. However, automated systems can show a high error rate against some antimicrobials. For this reason, comparing the results of automated system test results with tests such as E-test is very important to prevent both treatment failures and inappropriate antibiotic use that may occur on a patient basis. © 2022 by Author/s and Licensed by Modestum.Conference Object Late Presentation of Isolated Interrupted Aortic Arch: an Extremely Rare Congenital Anomaly(Elsevier Ireland Ltd, 2011) Bugan, B.; Iyisoy, A.; Celik, T.; Kucuk, U.; Boz, U.; Celik, M.; Demirkol, S.Conference Object The Role of Intravascular Ultrasound in The Management of Right Coronary Artery Dissection Due To Coronary Angiography(Elsevier Ireland Ltd, 2011) Celik, M.; Iyisoy, A.; Celik, T.; Bugan, B.; Demirkol, S.; Yuksel, U. C.Conference Object Torsades De Pointes Triggered by Early Ventricular Escape Beats in a Patient With Complete Atrioventricular Block(Elsevier Ireland Ltd, 2013) Yuksel, U. C.; Yildirim, E.; Kabul, H. K.; Celik, M.; Kucuk, U.; Bugan, B.; Gormel, S.