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Browsing by Author "Demirel, A."

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    Angiocentric Glioma Manifesting as Psychotic Symptoms in an Adolescent: a Case Report
    (2013) Kadak, M.T.; Demirel, A.; Demir, T.
    Cerebral cortical malformations can be associated with psychotic symptoms, and frontal, temporal, and limbic lesions may lead to psychosis-like symptoms. Therefore, these regions have a role in the pathogenesis of psychosis and related symptoms. Here, we report a 13-year-old adolescent who presented with auditory and visual hallucinations, persecutory delusions, and aggression. The patient's symptoms remitted after the resection of the left temporal lobe, fusiform gyrus, uncus, amygdala, and hippocampus. Histological examination revealed angiocentric glioama. We discuss the relationship between psychotic symptoms and the neural network that links the frontal lobe with limbic structures and how it can be disturbed by developmental abnormalities. © 2013 Elsevier GmbH.
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    Cardiac Tamponade During Methotrexate Treatment in a Patient With Rheumatoid Arthritis; Is It Due To Viral Infection, Rheumatoid Arthritis or Methotrexate Therapy?: Case Report
    (2003) Adak, B.; Ediz, L.; Budancamanak, M.; Demirel, A.
    Here we describe a Rheumatoid Arthritis (RA) patient who died due to cardiac tamponade during methotrexate (Mtx) treatment while her synovitis remained inactive. Mtx is an effective therapy for articular and extraarticular manifestations of RA and currently most widely used disease modifying antirheumatic drug (DMARD). However Mtx on occasion may play a role in facilitating the development of the extra-articular manifestations of RA in some rare cases. In this case report, the causes of cardiac tamponade in patients with RA during Mtx therapy and the efficacy of Mtx on the life expectancy in patients with RA discussed by review the literature.