Browsing by Author "Den Hartigh, Ozden Savas"

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    The Association of Left Ventricular End-Diastolic Pressure With Global Longitudinal Strain and Scintigraphic Infarct Size in St-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
    (Springer, 2021) Cap, Murat; Erdogan, Emrah; Karagoz, Ali; Den Hartigh, Ozden Savas; Acar, Rezzan Deniz; Gecmen, Cetin; Ozdemir, Nihal
    Left ventricular end-diastolic pressure (LVEDP) is an independent predictor for prognosis in ST-elevation myocardial infarction (STEMI) patients. We aimed to investigate the relationship of admission LVEDP measured after a successful primary percutaneous coronary intervention (pPCI) with scintigraphic infarct size (IS) and global longitudinal strain (GLS), a strong predictor of IS, in STEMI patients. A total of 62 consecutive patients with STEMI were enrolled in the study. LVEDP measurements were performed after pPCI in patients who had TIMI-3 flow. Echocardiography was performed 24 h after pPCI and repeated 3 months later. GLS was calculated as an average peak strain from the 3 apical projections. IS was evaluated at the third month by technetium 99m sestamibi. The mean age was 56 +/- 8 years in the study population. The mean LVEDP was found 19.4 +/- 4.4 mmHg. Median IS was 4% (0-11.7 IQR).The mean GLS at the 24th hour and the third month were found to be - 15.4 +/- 2.8 and - 16.7 +/- 2.5 respectively. There was a moderate negative correlation between LVEDP and GLS (24th-hour p < 0.001 r = - 0.485 and third-month p < 0.001 r = - 0.489). LVEDP had a moderate positive correlation with scintigraphic IS (p < 0.001 r = 0.545). In the multivariable model, we found that LVEDP was significantly associated with scintigraphic IS (beta coefficient = 0.570, p = 0.008) but was not associated with the 24th hour (beta coefficient = 0.092, p = 0.171) and third month GLS (beta coefficient = 0.037, p = 0.531). This study demonstrated that there was a statistically significant relationship between LVEDP and scintigraphic IS, and IS was increased with high LVEDP values. However, there was not a relationship between LVEDP and GLS.