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Browsing by Author "Deveci, Ozcan"

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    Does Neutrophil / Lymphocyte Ratio Contribute To Diagnostics in Patients With Fascioliasis
    (Carbone Editore, 2018) Cicek, Mutalip; Deveci, Ozcan; Cengiz, ZeynepTas; Bilden, Alican; Bilik, Ozge Alkan
    Introduction: Fasciolia sp. is a trematode causes infection by settling in the liver bile ducts of domestic animal and human liver. Fascioliasis is a parasite disease that might have changes in liver parenchyma and in bile ducts. Many inflammatory reactions occur during the settlement of larvae and mature parasites into the liver. The neutrophil/lymphocyte ratio (NLR) has become a prominent marker of underlying inflammation. The objective of the present study is to investigate the relationship between the hematological parameters in patients with fascioliasis. Materials and methods: The diagnosis of fascioliasis was based on patient history, clinical and laboratory findings, radiological imaging (ultrasound), stool examination and IgG antibody titer determination by ELISA. Clinical and laboratory data were collected for 56 patients with fascioliasis, and diagnosed with serological and radiological imaging. 56 healthy volunteers were selected for the control group. Stool and blood samples were collected from patients with fascioliasis for serologic, biochemical, hematologic tests and ova examination. Total leukocyte, neutrophil, eosinophil and lymphocyte counts were recorded and NLR was calculated. ELISA antibody cut off titer value of patients with fascioliasis was 10> positive. Results: We compared neutrophil/lymphocyte ratio, eosinophil/lymphocyte ratio, the relation of eosinophilia and IgG antibody titers between two groups (patient and control groups). There was no statistically significant difference between patients and healthy controls neither based on age and gender nor NLR. According to these findings, NLR can not be considered as a diagnostic marker in fascioliasis. Conclusion: As a result, it was determined that NLR is not a crucial indicator of inflammation in parasitic fascioliasis. Extensive studies are need to be done to clarify the correlation between NLR and progression of other parasitic diseases.
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    Fibromyalgia Incidence Among Patients With Hepatitis B Infection
    (Wiley, 2016) Yazmalar, Levent; Deveci, Ozcan; Batmaz, Ibrahim; Ipek, Davut; Celepkolu, Tahsin; Alpayci, Mahmut; Sariyildiz, Mustafa A.
    Aim: The purpose of our investigation was to evaluate the incidence of fibromyalgia syndrome (FMS) and identify FMS-related clinical symptoms in hepatitis B virus (HBV) patients. Methods: One hundred and eighteen HBV surface antigen (HbsAg)-positive patients (40 with chronic active hepatitis B, 40 hepatitis B carriers and 38, all of whom had been antiretroviral-treated for at least 3 months) were included in this study. In addition, 60 age- and gender-matched HbsAg-negative healthy controls were included in the study. Results: There was no significant difference in age, gender or body mass index (BMI) between the two groups (P > 0.05). Serum aspartate aminotransferase and alanine aminotransferase levels were significantly higher in HBV patients relative to the control group (P < 0.05). The incidence of FMS, widespread body pain, fatigue, sleep disturbance, anxiety, morning stiffness, arthralgia was significantly greater among HBV patients relative to the control group. Additionally, the mean tender point counts and the visual analog scale values were significantly higher among the HBV patients (P < 0.05). Conclusions: The results of the present study demonstrate that FMS incidence is greater among HBV patients relative to control subjects. However, there were no differences in FMS incidence among the subgroups of HBV diagnoses.