Browsing by Author "Dilek, F.H."

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Cholesterol Granuloma of the Maxillary Sinus. a Case Report
(1997) Dilek, F.H.; Kiriç, M.; Uǧra̧, S.
A patient with cholesterol granuloma of the maxillary sinus with hypercholesterolemia is presented.
Elastosis Perforans Serpiginosa
(1997) Dilek, F.H.; Ugras, S.; Akpolat, N.
A 21-year-old male with brown keratotic papules on the nape of his neck was admitted to our clinic. Lesions were in characteristic arcuate and serpiginous patterns. The diagnosis of elastosis perforans serpiginosa (EPS) was confirmed by skin biopsy. The pathogenesis of EPS is still unclear. There is evidence for the transepidermal elimination of morphologically and biochemically abnormal elastic fibers. EPS was described in idiopathic, penicillamine induced and connective tissue disorder associated forms. In this article, we described and discussed the clinical and morphologic data in view of the literature.
The High Prevalence of Esophageal and Gastric Cancers in Eastern Turkey
(1998) Turkdogan, M.K.; Akman, N.; Tuncer, I.; Dilek, F.H.; Akman, E.; Memik, F.; Aksoy, H.
Background/Aims: Gastrointestinal cancers (G.I Ca) are important causes of mortality in Eastern Turkey. We purposed to reveal the epidemiological characteristics and the regional risk factors of the upper G.I (esophageal and gastric) cancers. Materials and Methods: 203 G.I Ca patients were diagnosed in our Gastroenterology Department with endoscopic, radiological and histopathological methods in two and half years. Their age, sex, nutritional habits and the histopathologic types of cancers were determined. Results: Esophageal and gastric cancers were ninety percent (183/203) of all the G.I Ca. Gastric and esophageal cancers were ninety percent (90%) of all these GI cancers. Both of cancer groups have been generally diagnosed after fifty years of age, and gastric Ca was twice frequent in males, whereas esophageal Ca was one and half times frequent in females. Drinking hot tea and family history of cancer were significant in the esophageal Ca group, although cigarette smoking was not significantly different in both cancer groups than the control group. Daily dietary habits were generally consumption of hot, salted, fatty, smoked and fried foods (meat, cereals etc.) without sufficient intake of fresh fruits and vegetables. Histopathologically, ninety percent (90%) of esophageal Ca were epidermoid carcinoma and ten percent (10%) were adencarcinoma whereas all gastric Ca were adenocarcinoma. Conclusions: There are many carcinogen risk factors including mainly dietary and ecological factors such as stagnant ditch water, animal manure and peat in rural areas and volcanic soil properties in the Van region.
Nitric Oxide Oxidation Products in the Serum of Patients With Gastric and Esophageal Cancer and Helicobacter Pylori
(1999) Turkdogan, M.K.; Testereci, H.; Kahraman, T.; Dilek, F.H.; Akman, E.
Nitric oxide (NO) oxidation products (nitrate and nitrite) were analysed in the serum of 12 gastric cancer (Ca), (12 gastric Ca, 12 esophageal Ca) and 12 healthy controls with modified Stahr's method. Helicobacter pylori (H. pylori) infection was diagnosed histopathologically in the gastric cancer and control groups. In the gastric Ca group mean, serum nitrate and nitrite levels (11.65 ppm and 3.40 ppm) were significantly higher than the esophageal Ca and control groups (p<0.05 and p<0.001). In the esophageal Ca group the mean serum nitrate level (7.16 ppm) was higher than the control group (4.73 ppm, p<0.05) while the nitrite level (1.53 ppm) was not significantly different from the control group (1.70 ppm). H. pylori infection was significantly higher in the gastric Ca group (56.40%) than the control group (36.66%, p<0.05). In conclusion, we observed the highest serum NO product levels in the gastric Ca group although the dietary intake of nitrated foods was similar in both of the Ca groups. This observation indicates the important role of H. pylori infection in the etiopathogenesis of gastric cancer related to the synthesis of NO and consequent the carcinogen nitroso compounds.
Prophylactic Appendectomy : Is It Worth To Be Done
(ARSMB-KVBMG, 2001) Dilek, O.N.; Güler, O.; Güler, A.A.; Demirtas, I.; Altindis, M.; Dilek, F.H.; Özgören, E.
There are still many controversial issues in prophylactic appendectomy. In this retrospective study, we have appraised the reasons and results of prophylactic appendectomies performed between January 1997 and August 1999. Sixty four prophylactic appendectomy cases were included in this study and all resected specimens were submitted to histopathological analysis. In 23 patients with incisional hernias, a prophylactic appendectomy was performed as, in the future, dense adhesions may lead to difficult appendectomy. Additional appendectomy had no negative effect on perioperative complications, compared with the patients without appendectomies. In conclusion, in the presence of optimal conditions, prophylactic appendectomy can be performed safely.
Protection of Intestinal Anastomoses in Septic Environment With Peritoneal Graft and Polyglycolic Acid Mesh : an Experimental Study
(ARSMB-KVBMG, 1996) Dilek, O.N.; Bakir, B.; Dilek, F.H.; Demirel, H.; Yiǧit, M.F.
We carried out an experimental study in dogs to evaluate the outcome of large bowel anastomosis with 6 stitches (Group C, n : 6) in a septic environment with protection by a polyglycolic acid (PGA) mesh (Group M, n : 12) or peritoneal graft (Group P, n : 12). Thirty dogs were used to compare the techniques. Two dogs in each group were re-operated after 3, 5, 7, 14, 28 and 90 days. They were evaluated for adhesion formation, lumen diameter (anastomotic index), clinical features, histologic appearance and quality of healing at the anastomotic sites. All dogs in group P and group M survived, whereas 2 dogs in the control group died of anastomotic leakage and 3 dogs were re-operated for anastomotic leakage and peritonitis. In group M, one dog was reoperated because of the anastomotic leakage and two dogs were reoperated because of the anastomotic stenosis. Also, 4 anastomoses showed evidence of moderate stenosis. In group P, three anastomoses were graded as minimal stenosis. Histopathologic evaluation showed more complete epithelization, less inflammation, and less adhesion in group P than group M. We could not find any study in the literature that described and compared both techniques. We report here the results of such a study.