Browsing by Author "Durmaz, Fatma"

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Akciğer Bilgisayarlı Tomografisinde Sık Görülen Mozaik Perfüzyon Etyolojisinderadyolojik İpuçları
(2020) Sünnetçioğlu, Aysel; Dündar, İlyas; Göya, Cemil; Özgökçe, Mesut; Durmaz, Fatma
Amaç: Bu çalışmamızda günlük radyoloji pratiğinde akciğer bilgisayarlı tomografide (BT) sık karşılaştığımız mozaik atenuasyon (MA) paterni olan hastalarda altta yatan süreci tanımlamaya yönelik, görüntüleme bulgularının radyolojik ipuçlarını literatür eşliğinde sunmayı amaçladık.Gereç ve Yöntem: MA paterni olan 400 hastanın toraks BT’si retrospektif olarak incelendi. Görece lüsen alanların mı (mozaik perfüzyon); yoksa görece opak alanların mı (buzlu cam) anormal olduğunu belirlemek için öncelikle damar çaplarına bakıldı. Damar çapı lüsen alanda daha küçük ise bu alan patolojik kabul edildi. Sonra mozaik perfüzyon nedenleri vasküler mi küçük hava yolu hastalığı mı diye direkt ve indirekt bulgulara bakıldı. Mozaik perfüzyonun havayolu hastalığı bulgularından bronş duvarı kalınlaşması, tomurcuklanmış ağaç görünümü ve bronşektazi direk; santral yerleşim, lobüler görünüm, küçük ve keskin kenarlı lüsen alanlar ise indirekt bulgular olarak kabul edildi. Vasküler nedenli MA’nun direk bulguları trombüs ve pulmoner arter genişlemesi iken periferal yerleşim, daha büyük ve sınırları net olmayan lüsen alanlar ise indirek bulgular olarak kabul edildi. Daha sonra bulgular klinik sonuçlar ile de korele edildi.Bulgular: MA’nın nedeni 190 (%47.5) hastada buzlu cam olarak tespit edildi. Lüsen alanların patolojik olduğu 210 hastanın 140’ı (%67) küçük hava yolu ve 70’i (%33) vasküler nedenli idi. Hava yolu hastalığına bağlı mozaik perfüzyon olan hastalarda toraks BT’de en sık tomurcuklanmış ağaç, bronş duvarında kalınlaşma ve bronşektazi izlendi. Vasküler hastalığa bağlı mozaik perfüzyonda ise kronik pulmoner emboli ve pulmoner hipertansiyon bulguları eşlik etmekteydiSonuç: Mozaik atenuasyon paterni düşünüldüğü kadar nonspesifik bir bulgu olmayıp radyologlar tarafından sistematik bir yaklaşım ile BT bulguları değerlendirilerek ayırıcı tanıya ve tedaviye katkı sunulabilir.
The Association of Vascular Loops of Anterior Inferior Cerebellar Artery and Vestibulocochlear Symptoms
(Wolters Kluwer Medknow Publications, 2023) Dadali, Yeliz; Ozkacmaz, Sercan; Avcu, Mustafa; Alpaslan, Muhammed; Goya, Cemil; Ozgokce, Mesut; Durmaz, Fatma
Aim: The association of vascular loops of anterior inferior cerebellar artery (AICA) with vestibulocochlear symptoms including hear loss, tinnitus, and vertigo is controversial. We aimed to investigate the relationship between vestibulocochlear symptoms and AICA vascular loop syndrome on magnetic resonance imaging (MRI). Materials and Methods: The patients underwent a posterior fossa MRI examination were reviewed regarding the presence of hear loss, tinnitus, and vertigo by an experienced ear-nose-throat specialists' physical examinations. The incidences of these lesions in the patients with and without AICA vascular loop syndromes were compared. Furthermore, the correlation between the AICA vascular loop syndrome subtypes (grade 1-3) and the incidence of the symptoms were analyzed. Results: A total of 502 patients (1004 ears) were included in this study. Vascular loops were demonstrated in 150 ears (14.9%). Subtype 1 was observed in 97 (9.7%), subtype 2 in 40 (4.0%) and subtype 3 in 13 (1.3%) ears. The incidences of tinnitus, hear loss, and tinnitus + hear loss were statistically significantly higher in the patients with vascular loops than without vascular loops (p: 0.000042, p: 0.0446906, p: 0.028106, respectively). However, there was not a significant correlation between the incidence of the symptoms and the grade of the vascular loop formation (p>0.05). Vertigo incidence was very similar among the patients with no, with one-sided and with both-sided AICA vascular loops (41.5%, 39.8% and 46.2%, respectively) with no statistical difference (p>0.05). Conclusion: The AICA vascular loop is associated with either tinnitus or hear loss but there is no correlation with the degree of the vascular loops. There is no relationship between AICA vascular loops and vertigo.
Çölyak Hastalarında Pelvik Venöz Dilatasyonunun Bilgisayarlı Tomografi İle Değerlendirilmesi
(2022) Ayyıldız, Veysel Atilla; Özgökçe, Mesut; Özkaçmaz, Sercan; Durmaz, Fatma; Göya, Cemil; Dündar, İlyas; Türko, Ensar
Amaç Çölyak hastalığı (ÇH), genetik olarak glutene duyarlı bireylerde, ince bağırsağın enflamatuar hasarına yol açan bir immün yanıt ile karakterizedir. Pelvik venöz dilatasyonun (PVD) radyolojik olarak tanımlanması, pelvik ve sistemik hastalıkların farklı spektrumlarının teşhisine katkıda bulunabileceğinden önemlidir. Çalışmamızda ÇH olanlarda PVD prevalansını belirlemeyi ve bulgularımızı literatür eşliğinde sunmayı amaçladık. Gereç ve Yöntem Bu retrospektif gözlemsel çalışma, kurumumuzdaki etik kurulu tarafından onaylandı. ÇH tanısı alan tüm hastalar, klinik değerlendirme, serolojik veriler ve bağırsak biyopsisi olan ve Ekim 2011-Mart 2020 tarihleri arasında tıp merkezimizde Bilgisayarlı Tomografisi (BT) çekilen hastalardı. Kontrastlı BT yapılan ÇH olanlar (n=149) ve kontrol grubu (n=250) PVD açısından değerlendirildi. Hasta ve kontrol grubundaki tüm hastalarda PVD prevalansı incelendi. Pelvik damarların çapı ölçüldü ve not edildi. Hastaların şikayetleri hastane kayıtlarından not edildi. Bulgular Histopatolojik olarak kanıtlanmış toplam 149 hasta grubunda, yaş ortalaması sırasıyla 35,11 ± 13,03 ve 36,23 ± 15,06 yıl olan 93 kadın ve 56 erkek hasta vardı. Toplam 250 kontrol grubu arasından; yaş ortalaması sırasıyla 38,65 ± 15,38 ve 37,25 ± 13,56 yıl olan 145 kadın ve 105 erkek vardı. Kadın ve erkekte PVD prevalansı ÇH’larında sırasıyla %60,22 (n=56) ve %41,07 (n=23) idi. ÇH’nın %46,75’inde (n=36) karın ağrısı vardı ve PVD ile korele idi (p < 0.05). Mezenterik engorjman ve ince bağırsak kıvrım anormallikleri PVD ile korele idi (p < 0,05). Sonuç Pelvik konjesyon sendromu, kadınlarda çok yaygın olan ve potansiyel olarak önemli sakatlıklara yol açabilen PVD'nin neden olduğu düşünülen kronik pelvik ağrının nedenlerinden biridir. Karın ağrısı, ÇH'de görüntüleme yöntemlerinin uygulanmasının önemli bir nedenidir. Çalışmamızda ÇH hastalarında karın ağrısı PVD ile korele idi. Ayrıca, PVD prevalansı oldukça yüksekti. Dolayısıyla, ÇH olanlarda kontrastlı BT'de görülen artmış PVD prevalansı pelvik şikayetlerin bir bileşeni olabilir.
The Comparison of Wall Thickness of Esophagus and Gastroesophageal Junction Using Computed Tomography With Endoscopy and Biopsy Results
(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2020) Durmaz, Fatma; Ozgokce, Mesut; Toprak, Nursen; Oguzlar, Furkan Cangin; Goya, Cemil
Background: This study aims to establish a cut-off value for increases in the esophageal wall thickness measured using computed tomography to differentiate between benign and malignant pathologies. Methods: A total of 144 patients (61 males, 83 females; mean age 57.2 +/- 12.4 years; range, 24 to 86 years) who underwent thoracic and/or abdominal computed tomography in the radiology clinic between January 2015 and June 2018 for any reason and who were found to have a thickening of the esophageal wall or gastroesophageal junction were retrospectively analyzed. Tomography images were examined by two radiologists who reached consensus on the wall morphology and thickness, anatomic localization, and any accompanying findings regardless of the endoscopy results. Benign and malignant patients were identified from the endoscopy and/or biopsy results. The receiver operating characteristic analysis was carried out to establish a cut-off value for the lesion wall thickness to differentiate between benign and malignant pathologies and to determine a cut-off value for the lesion-level thickness-normal segment thickness ratio. Results: A statistically significant difference was found in the wall thicknesses of patients with esophageal cancer and those with benign lesions. According to a cut-off value for wall thickness of 13.5 mm, sensitivity and specificity were found to be 94.3% and 100%, respectively. The lesion-level thickness-normal segment thickness ratio was found to be statistically significant in malignant-benign differentiation, and a significant correlation was found between the asymmetric thickening and malignancy. Conclusion: Increases in the esophageal wall thickness and asymmetry detected on computed tomography can contribute to the early diagnosis of esophageal cancers, particularly in regions endemic to esophageal cancer as in Van province in eastern anatolia region of Turkey. Asymmetric wall thicknesses over 13.5 mm would be highly significant in terms of malignancy in tomographic examinations.
The Comparison of Wall Thickness of Esophagus and Gastroesophagial Junction Measured in Computed Tomography With Endoscopy and or Biopsy Results
(2019) Durmaz, Fatma; Göya, Cemil
ÖZET Amaç: Endoskopi ve/veya biyopsisi yapılan hastaların, özofagusun kesite girdiği abdomen ve toraks BT görüntülerinde ölçülen, özofagus cidar kalınlık artışlarının benign ve malign patolojiler açısından ayırımını yapabilecek bir eşik değer bulmayı amaçladık. Materyal-metot: Ocak 2015-Haziran 2018 tarihleri arasında Radyoloji kliniğinde herhangi bir nedenle toraks ve/veya abdomen bilgisayarlı tomografisi çekilen, özofagus yada gastroözofagial bileşkede kalınlık tespit edilen hastalar retrospektif olarak incelendi. Yaşları 24-86 yaş arasında değişen 61 erkek, 83 kadın toplam 144 hasta çalışmaya alındı. Çalışmamızda tüm hastaların endoskopi sonuçları mevcut iken bu hastaların 69'unda biyopsiye ihtiyaç duyulmuştur. Hastanın ön tanısına göre çeşitli protokollerde alınan tomografi görüntüleri iki radyolog tarafından, endoskopi sonuçlarına bakılmaksızın görüş birliğine varılarak duvar morfolojisi, kalınlığı, anatomik lokalizasyonu ve eşlik eden bulgular açısından incelendi. Sonrasında endoskopi ve/veya biyopsi sonuçlarına göre benign ve malign hastalar belirlendi. Lezyon duvar kalınlıkları ile benign-malign ayrımında cut-off değeri belirlemek için ROC analizi yapıldı. Aynı zamanda benign ve malign durumlarda asimetri görülmesi açısından da Ki-Kare testi yapılmıştır. Gerekli istatistiksel analizler SPSS 22 istatistik yazılım programı kullanılarak yapılmıştır. Bulgular: Özofagus kanserli olgular ile benign durumlar arasında cidar kalınlığında istatistik olarak anlamlı fark saptandı. Cidar kalınlığı için kesim değeri 13.5 alındığında senstivite %94.3 spesifite değeri ise %100 olarak belirlenmiştir. Lezyon düzeyindeki kalınlığın normal segment kalınlığına oranı malign-benign ayrımında istatistiksel olarak anlamlı saptandı. Asimetrik kalınlaşma ile malignite arasında anlamlı ilişki bulundu. Özofagus kanserinin histolojik tipinin çoğunu SCC (%79.2) ve adenokanser (%13.3) oluşturmaktaydı. En sık yerleşim yeri özofagusun distal kesimiydi. SCC'lerin çoğunluğu orta ve distalde, adenokanserlerin tamamı distalde görüldü. Benign lezyonların çoğu distalde izlendi. En sık tanı özofajitti. Sonuç: Yöremizde sık görülmesi nedeniyle özofagus kanseri erken tanısında BT'nin katkı sunacağını düşünmekteyiz. Anahtar Kelimeler: Özofagus Kanseri, Özofagus Cidar kalınlığı, Bilgisayarlı Tomografi
Dev Duodenum Divertikülü: Radyolojik Bulgular
(2016) Yokuş, Adem; Durmaz, Fatma; Ozgokce, Mesut; Batur, Abdussamet
Duodenum divertikülü az bilinen bir patolojidir.Divertiküller genellikle semptom vermezler, sıklıklagastrointestinal görüntüleme yöntemlerinde tesadüfensaptanmaktadırlar. Bu yazımızda, duodenum 1.segmentte yerleşmiş, yaklaşık 5x3 cm boyutunda dev birduodenum divertikülü olgusunu sunuyoruz
Does Contrast-Enhanced Computed Tomography Raise Awareness in the Diagnosis of the Invisible Side of Celiac Disease in Adults
(Springer, 2022) Goya, Cemil; Dundar, Ilyas; Ozgokce, Mesut; Turko, Ensar; Ozkacmaz, Sercan; Durmaz, Fatma; Hattapoglu, Salih
Purpose This study aimed to evaluate the diagnosis and determine major and minor criteria of celiac disease (CD) with the malabsorption patterns (MABP) in the small intestine and colon on computed tomography (CT) and additional CT findings. Methods This retrospective study was conducted with 116 patients diagnosed with CD, 14 CD patients recovering with treatment, and 35 control patients with non-CD. All patients had CT examinations and histopathological diagnoses. The sensitivity, specificity, PPV, NPV, and accuracy values of each CT finding defined in the literature were statistically evaluated. According to the patient and control groups, the numerical values of the findings and the sensitivity and specificity values were measured according to this cut-off value. The distribution of CT findings according to pathological Marsh data was evaluated in CD patients. Results Sensitivity and specificity were found to be higher in small bowel MABP findings, mesenteric hypervascularity, and increased SMV/aorta diameter. There was a numerically significant difference in MDCT findings between the control and pathological Marsh groups. In the ROC analysis performed in terms of the total numerical values of each MDCT finding observed between the groups, it was found that there were more than 7 MDCT findings, 100% sensitivity, and 92% specificity. The presence of four major and three minor criteria or three major and four minor criteria were considered significant. Conclusions Being aware of CT findings below the iceberg that may suggest CD in abdominal CT examinations performed in patients with atypical clinical and malabsorption findings or other nonspecific findings may prevent diagnostic delay and unnecessary procedures. [GRAPHICS] .
Doubling Time in Pulmonary and Hepatic Hydatid Cysts
(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2024) Aydin, Yener; Ozgokce, Mesut; Ulas, Ali Bilal; Durmaz, Fatma; Kasali, Kamber; Eren, Suat; Eroglu, Atilla
Background: This study aims to investigate whether the concept of doubling time in hydatid cysts differs according to different parameters such as age, sex, and whether the cyst is located in the lung or liver. Methods: Between January 2012 and August 2023, a total of 138 hydatid cysts were retrospectively analyzed. There were 55 pulmonary (32 males, 23 females; mean age: 25.6 +/- 23.8 years; range, 2 to 77 years) and 83 hepatic hydatid cyst patients (32 males, 51 females; mean age: 31.1 +/- 22.8 years; range, 3 to 75 years). Results: The mean doubling times for pulmonary and hepatic hydatid cysts were 73.4 +/- 41.8 and 172.6 +/- 108.8 days, respectively (p<0.001). When children (<= 18 years old) and adult cases were compared for pulmonary hydatid cysts, the mean doubling times were 61.1 +/- 17.6 and 87.1 +/- 55.3 days, respectively (p=0.119), and for hepatic hydatid cysts, 110.6 +/- 48.4 and 215.6 +/- 118.3 days, respectively (p<0.001). While comparing male and female cases, the mean doubling time for pulmonary hydatid cysts was 77.6 +/- 32.2 and 67.6 +/- 52.6 days, respectively (p=0.018), while for hepatic hydatid cysts, it was 192.0 +/- 111.7 and 160.4 +/- 106.2 days, respectively (p=0.250). Conclusion: The doubling time seems to be approximately 10 weeks in the lung and approximately 25 weeks in the liver. Hydatid cysts grow faster in children than adults in both the lungs and liver.
Efficacy of Shear Wave Elastography in Malignity Assessment of Thyroid Nodules With Atypia of Undetermined Significance and Comparison With Ti-Rads
(Bayrakol Medical Publisher, 2022) Durmaz, Fatma; Ozgokce, Mesut; Ozkacmaz, Sercan; Dundar, Ilyas; Alay, Murat; Goya, Cemil; Kotan, Mehmet Cetin
Aim: The aim of this study is to investigate the effectiveness of shear wave elastography (SWE) in the differentiation of benign-malignant thyroid nodules diagnosed with atypia of undetermined significance (AUS) and to compare with the American College of Radiology (ACR)-thyroid imaging reporting and data system (TIRADS). Material and Methods: This monocentric study comprised 52 patients (9 males; 43 females) who were diagnosed with AUS by thyroid FNAB. All patients included in the study had gray scale ultrasound (US) and SWE images. The mean SWE value was calculated for each nodule, and TIRADS scores were determined based on the US. The obtained data were compared based on the histopathological result in patients who had undergone surgical treatment, and based on the cytology result in patients followed-up by FNAB, for the differentiation of benign and malignant nodules. Results: Nineteen patients were found to have malignant nodules and 33 had benign nodules. The mean SWE was 2.89 +/- 0.51 (2.30-3.92) and 2.91 +/- 0.48 (2.16- 3.79) in the malignant and benign cases, respectively. The results of independent T-tests between the two groups were insignificant (p=0.89). TIRADS 2-3 (total 29 patients) nodules were considered possibly benign, and TIRADS 4-5 (total 23 patients) possibly malign, the sensitivity, specificity, positive predictive and negative predictive value of TIRADS were identified 100%, 87.9%, 82.6% and 100%, respectively, when compared with the pathology results. Discussion: There was no significant difference in SWE values in the differentiation of malignant-benign thyroid nodules with AUS. However, the ACR-TIRADS criteria still maintain their importance.
Efficacy of Shear Wave Elastography in the Differentiation of Acute and Subacute Deep Venous Thrombosis
(Lippincott Williams & Wilkins, 2021) Durmaz, Fatma; Gultekin, Mehmet Ali
It is important to know the age of clot formation to determine an appropriate treatment for deep vein thrombosis (DVT). The present study aims to differentiate between acute and subacute DVT using the shear wave elastography (SWE) technique. Patients with complaints no longer than 4 weeks and who were found to have early-stage (acute-subacute) thrombus on ultrasound (US) between January 2020 and May 2020 were included in the study. All of the patients underwent SWE using a Philips Healthcare EPIQ 5 Ultrasound System Inc. device with a high-resolution linear US probe (eL18-4, 22-2 MHz). Included in the study were 50 patients, including 23 with acute DVT and 27 with subacute DVT. Of the patients, 22 were women and 28 were men, and the mean age was 46.32 +/- 11.33 years (range: 24-74 years). The mean SWE value was 2.63 +/- 0.16 (2.39-2.96) in patients with acute DVT and 3.34 +/- 0.31 (2.65-3.88) in patients with subacute DVT. The findings were statistically significant in the comparison of the 2 groups using an independent samples t test (P < 0.001). In the receiver operating characteristic analysis, the area under the curve was found to be 97.6%. When the cutoff value was taken as 2.85 according to the area under the curve, sensitivity was found to be 96.3%, and specificity was 91.3%. Thrombus stage plays a critical role in treatment decisions in DVT in the lower extremities. The present study reveals that the shear wave US elastography technique can be used to discriminate between acute and subacute DVT.
The Efficiency of Acoustic Radiation Force Impulse (Arfi) Elastography in the Differentiation of Renal Cell Carcinoma and Oncocytoma
(Bentham Science Publ Ltd, 2024) Ozgokce, Mesut; Dundar, Ilyas; Durmaz, Fatma; Ozkacmaz, Sercan; Kankilic, Nazim A.; Aslan, Rahmi; Akinci, M. Bilal
Purpose This study is to investigate the effectiveness of Acoustic Radiation Force Impulse (ARFI) elastography in differentiating radiologically similar renal cell carcinoma (RCC) and oncocytoma in solid masses of the kidney. Methods The patients with solid renal mass histopathological diagnosed after excision or tru-cat biopsy who underwent a preoperative ARFI elastography of the lesion during a 4-year period were included in this study. Preoperative shear wave velocity (SWV) values were measured in all the lesions. SWV results of RCCs and oncocytomas were compared by an independent t-test, and cut-off, sensitivity and specificity values were calculated. Results Forty-two of the 60 patients included in the study were men (70%) and, 18 were women (30%), and the mean age was 59.7 +/- 14 (27-94) years. Among 46 RCCs (76.6%), 23 and 14 oncocytomas, 5 (23.4%) were located in the right kidney (p:0.34722). Mean SWV values were found to be significantly higher in RCCs (2.87 +/- 0.74 (0.96-4.14) m/s) than oncocytomas (1.83 +/- 0.78 (0.80-3.76) m/s) (p <0.001). In the ROC analysis, a cut-off value of 2.29 m/s was found to havean 80.4% sensitivity and a 78.6% specificity for the discrimination of RCCs from oncocytomas. Conclusion ARFI elastography measurements may be useful in distinguishing RCC and oncocytomas that may have similar solid radiological imaging features.
The Efficiency of Diffusion-Weighted Magnetic Resonance Imaging in the Differentiation of Malign and Benign Cavitary Lung Lesions
(Lippincott Williams & Wilkins, 2023) Durmaz, Fatma; Ozgokce, Mesut; Aydin, Yener; Yildiz, Hanifi; Ozkacmaz, Sercan; Dundar, Ilyas; Goya, Cemil
Purpose:The present study investigates the diagnostic efficiency of apparent diffusion coefficient (ADC) values in differentiating between malignant and benign cavitary lesions on diffusion-weighted magnetic resonance imaging (DWI). Materials and Methods:This prospective study included 45 consecutive patients identified with a cavitary lung lesion with a wall thickness of >= 5 mm on thoracic computed tomography in our clinic between 2020 and 2022, and who underwent thoracic DWI within 1 week of their original computed tomography. ADC measurements were made on DWI by drawing a region of interest manually from the cavity wall, away from the lung parenchyma in the axial section where the lesion was best demonstrated. The patients were then classified into benign and malignant groups based on the pathology or clinico-radiologic follow-up. Results:The sample included 29 (64.4%) male and 16 (35.6%) female patients, with a mean age of 59.06 +/- 17.3 years. Included in the study were 1 patient with 3 and 3 patients with 2 cavitary lesions each, with a total for the sample of 50 cavitary lesions. There were 23 (46%) malignant and 27 (54%) benign cavitary lung lesions. The mean ADC value (x10(-3) mm(2)/s) of the malignant and benign cavitary lesions was 0.977 +/- 0.522 (0.511 to 2.872) and 1.383 +/- 0.370 (0.930 to 2.213), respectively. The findings were statistically significant using an independent samples t test (P=0.002). The mean wall thickness of the malignant and benign lesions was 12.47 +/- 5.51 mm (5 to 25 mm) and 10.11 +/- 4.65 mm (5 to 22 mm), respectively. Although malignant cavities had a higher mean wall thickness than benign cavities, the difference was statistically insignificant (P=0.104). Conclusion:A significant difference was identified between the ADC values measured in DWI of the malignant and benign cavitary lung lesions. DWI, a noninvasive and rapid imaging method, can provide useful information for the differential diagnosis of cavitary lesions and can minimize unnecessary biopsies.
Efficiency of Diffusion-Weighted Mri for Differentiating Radiologically Similar Simple and Type I Hydatid Cysts of the Liver
(Sage Publications Ltd, 2022) Dundar, Ilyas; Ozgokce, Mesut; Durmaz, Fatma; Ozkacmaz, Sercan; Turkoglu, Saim; Goya, Cemil
Background Determining the nature of purely cystic hepatic lesions is essential because different kinds have different follow-ups, treatment options, and complications. Purpose To explore the potential of apparent diffusion coefficient (ADC) values of diffusion-weighted imaging (DWI) for the differentiation of type I hydatid cysts (HC) and simple liver cysts (SLC), which have similar radiological appearances. Material and Methods This single-center prospective study was conducted during 2016-2019. Round, homogenous, anechoic liver cysts >1 cm were classified according to at least two years of imaging follow-up, radiological features, serology, as well as puncture aspiration injection reaspiration procedure and pathology results. ADC values of 95 cysts (50 type I HCs and 45 SLCs) were calculated on DWI. The differences in ADC values were analyzed by independent t-test. Results Of 51 patients, 28 were female, 23 were male (mean age 32.07 +/- 22.95 years; age range 5-82 years). Mean diameter of 45 SLCs was 2.59 +/- 1.23 cm (range 1.2-7.6 cm) and ADC(mean) value was 3.03 +/- 0.47 (range 2.64-5.85) while mean diameter of 50 type I HCs was 7.49 +/- 2.95 cm (range 2.8-14 cm) and ADC(mean) value was 2.99 +/- 0.29 (range 2.36-3.83). There was no statistically significant difference in ADC values between type I HCs and SLCs Conclusion Some studies report that ADC values of type I HCs are statistically significantly lower than those of SLCs. Others suggest no significant difference. In our study with a higher number of cases, using ADC parameters similar to those in previous studies, we did not find any statistically significant difference.
Examining the Morphometric Features of Bulbus Oculi in Van Cats by Using Computed Tomography and Magnetic Resonance Imaging
(Ankara Univ Press, 2021) Yilmaz, Osman; Durmaz, Fatma
This study was conducted to obtain the morphometric and volumetric measurements of bulbus oculi of Van cats, growing around the city of Van in Turkey and named after here, by using computed tomography (CT) and magnetic resonance imaging (MRI), and to reveal the biometric differences of these measurement values between the sexes. A total of 16 adult Van cats including 8 females and 8 males were used in the study. The animals were anesthetized with the combination of xylazine and ketamine. The anesthetized animals were scanned by using CT and MRI devices and their images were obtained. Then, the morphometric and volumetric measurements of bulbus oculi were calculated from these images using the software (Syngo CT Software) in the workstation and their statistical analysis was performed. Upon the examination of the morphometric and volumetric analysis results, it was determined that while W (bodyweight) and ACL (Left Anterior Chamber) values were higher in male cats, DVLL (Dorsoventral length of the left lens) value was higher in female cats. These differences between the sexes were statistically significant (P<0.05). The volumetric measurement values of bulbus oculi and lens were determined to be averagely 4.60 +/- 0.27 cm(3) and 0.67 +/- 0.09 cm(3), respectively. In conclusion, the statistical differences of biometric values of bulbus oculi between male and female Van cats were determined by using CT and MRI. It is thought that the present study would contribute to the ophthalmological applications and the students receiving anatomy education.
Hidradenitis Suppurativa Accompanying Crohn's Disease With Multifocal Abscess
(2016) Arslan, Harun; Batur, Abdussamet; Alpaslan, Muhammed; Dundar, Ilyas; Durmaz, Fatma
Multifokal absesi olan yaşlı bir hastada Crohn hastalığı ve hidradenitis süpürativa birlikteliği sunmayı amaçladık. 81yaşındakadınhastaöksürük,kilokaybı,kasık bölgesinde kötü kokulu cerahat akıntısı ve çok sayıda ağrılışişlik şikayetleri ile başvurdu. Bilgisayarlıtomografide tüm gastrointestinal sistemde, subkutanöz alanda, mediastinal-hiler ve axiller bölgelerde multifokal abse odakları saptandı. Subkutanöz abse odağından alınan biyopsi sonucu hidradenitis süpürativa, kolonoskopide intestinal traktan alınan biyopsi sonucu Crohn hastalığıolarak geldi. Crohn hastalığı ve hidradenitis süpürativa birlikteliğinin farkındaolmakveyetersiztedaviyiönlemekiçingastrointestinalsisteminiyiaraştırılmasıbüyükönemtaşımaktadır.
Incidentally Detected Cardiac Hydatid Cyst: a Rare Case Report
(Soc Brasileira Medicina Tropical, 2025) Durmaz, Fatma; Kurt, Ferhat; Ozgokce, Mesut
İzole Dalak Metastazından Tanı Konulan Akciğer Adenokarsinomu
(2019) Ozgokce, Mesut; Koca, Hanifi; Durmaz, Fatma
Dalağın primer ve metastatik tümörleri lenfoma tutulumu dışında nadir görülür. Özellikle de izole dalak metastazı nadir görülmektedir. Biz 34 yaşında bir erkek hastada izole dalak metastazı yapan akciğer adenokarsinomu vakasını sunmaktayız. Çekilen toraks bilgisayarlı tomografi (BT) tetkikinde akciğerde santral kitlesi ve dalakta lezyonu olan olgunun dalaktan yaptığımız biyopsi sonucu adenokarsinom metastazı ile uyumlu şeklinde raporlandı. Vakamızın ilginç yanı izole dalak metastazından primer tümör tanısı konulmasıdır.
Klinik Olarak Anlamlı Prostat Kanserinin Tanısında Multiparametrik MRG'de Ölçülen ADC Oranlarının Rolu ve Gleason Skorları ile Korelasyonu
(2025) Özel, Enes; Dündar, İlyas; Durmaz, Fatma
Amaç: Bu çalışmanın amacı, prostat multiparametrik MRG (prostat mpMRG) ile elde edilen görünür difüzyon katsayısı (ADC) değerleri ve ADC oranlarının prostat glandındaki klinik olarak anlamlı kanserini (KOAK) ayırt etmedeki tanısal değerini araştırmak ve bu parametrelerin Gleason skorları ile olan ilişkisini değerlendirmektir. Gereç ve Yöntem: Ocak 2021 ile Ocak 2025 tarihleri arasında biyopsi öncesi prostat mpMRG yapılmış 188 hasta retrospektif olarak incelendi. Patolojik olarak GS ≥6 olan 62 hasta malign grup, benign özelliklerde veya normal doku tanısı olan 126 hasta benign grup olarak sınıflandırıldı. Tüm hastalara ait yaş, PSA, prostat volümü (PV), PSA dansitesi (PSAD) gibi klinik parametreler ile lezyon ve karşı zondan ölçülen ADC değerleri kayıt altına alındı. Malign grupta tümör bölgesi ADC (ADC-ML) ile aynı seviyedeki karşı zondaki normal alanın ADC (ADC-MN) oranı hesaplandı. Benign grupta ise şüpheli alanların ADC'si (ADC-BL) ile karşı zon normal alanın ADC'si (ADC-BN) oranlandı. Elde edilen veriler istatistiksel olarak analiz edildi. Bulgular: Malign lezyonların ADC ortalaması, benign dokuya göre istatistiksel olarak anlamlı şekilde daha düşük bulundu (p<0,001). ROC analizine göre ADC değeri için belirlenen cut-off 994 ×10⁻⁶ s/mm² olup, bu eşikte duyarlılık %96,8, özgüllük %94,0 olarak hesaplandı (AUC=0,994). ADC oranı için en iyi eşik değer 0,57 olarak saptandı ve bu değerde hem duyarlılık hem de özgüllük %95,2 idi (AUC=0,985). Gleason skorları ile ADC değerleri ve oranları arasında anlamlı negatif korelasyon saptandı (p<0,001). Ayrıca Gleason skoru ≥7 olan hastalarda karşı normal doku ADC'sinde de düşüş gözlenmesi, ADC oranlarını etkileyebilecek 'field cancerization' fenomenine işaret etmektedir. Sonuç: Prostat mpMRG'den elde edilen ADC değerleri ve oranları, prostat kanserinin tanısı ve agresifliğinin belirlenmesinde güvenilir ve tekrarlanabilir biyobelirteçlerdir. Bu çalışma, özellikle PI-RADS 2.1 sisteminde doğrudan tanımlanmayan ADC oranı kullanımının klinik fayda sağlayabileceğini göstermekte; bu parametrelerin, gelecekte farklı merkezlerde yapılacak geniş örneklemli çalışmalarla desteklenerek tanı sürecine entegrasyonu önerilmektedir.
A Life-Threatening Complication of Hydatid Cyst: Tension Pneumothorax
(Soc Brasileira Medicina Tropical, 2024) Aydin, Yener; Ozgokce, Mesut; Durmaz, Fatma
Measurement of Spleen Stiffness by Shear-Wave Elastography for Prediction of Splenomegaly Etiology
(Lippincott Williams & Wilkins, 2019) Batur, Abdussamet; Alagoz, Sumeyra; Durmaz, Fatma; Baran, Ali Irfan; Ekinci, Omer
Objective The aim of this study was to evaluate the reproducibility of measurement of spleen stiffness at the time of the initial detection of splenomegaly, whether it is found incidentally or not, in determining the etiology of splenomegaly. Methods The pathologies that brought about the diffuse splenomegaly were evaluated in 3 main groups as follows: hepatoportal, myeloproliferative, and infectious causes. In addition, 17 healthy control patients were recruited. All patients were examined with acoustic radiation force impulse imaging with VTQ. Results The difference between the splenic parenchymal elasticity values in the hepatoportal group (3.27 +/- 0.36 m/s), in the myeloproliferative disease group (2.98 +/- 0.33 m/s), in the infectious disease group (2.44 +/- 0.21 m/s), and in the control group (2.08 +/- 0.19 m/s) was found to be statistically significant (P = 0.001). The intraclass correlation coefficient for shear wave velocity measurement between hepatoportal causes and myeloproliferative causes was 71.2% (95% confidence interval [CI], 54.9%-87.4%), between hepatoportal causes and infective causes was 99.7% (95% CI, 98.6%-100.0%), and between myeloproliferative causes and infective causes was 83.3% (95% CI, 68.8%-97.9%). In the same patient groups, spleen volumes were measured as 64.08 +/- 9.66, 78.18 +/- 18.52, and 51.57 +/- 7.44 cm(2), respectively; in the control group, it was 26.75 +/- 6.57 cm(2). The difference between spleen volumes was found to be statistically significant (P = 0.001). Conclusions Distinguishing the causes of splenomegaly is important because the disorders require different management strategies. In diseases that cause splenomegaly, tissue content may change according to pathogenesis. Such changes in the spleen are mechanical properties that can be quantified by elastography.