Browsing by Author "Ermaya, Masallah"

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Investigation of Average Values of Prolidase, Adenozin Deaminase, Glutathione S-Transferase and Glutathione Reductase Enzymes in Pancreas Cancers
(Marmara Univ, inst Health Sciences, 2021) Ermaya, Masallah; Demir, Halit; Demir, Canan; Kanmaz, Huseyin
Objective: The purpose of this study is to determine the relationship between enzymatic antioxidants such as glutathione reductase and glutathione s-transferase and prolidase and adenosine deaminase in patients diagnosed with pancreatic cancer. Methods: Prolidase, adenosine deaminase, glutathione s-transferase and glutathione reductase activities were determined spectrophotometrically in blood sera collected from patients and healthy control subjects included in the study. Results: In patients with pancreatic cancer, the mean value of glutathione reductase and glutathione s-transferase enzymes decreased, while the mean value of prolidase, and adenosine deaminase, enzyme activities increased (p <0.05). Conclusion: In this study, in which prolidase, enzyme activity was first measured in pancreatic cancer, high prolidase, activity can be evaluated as a factor that increases the risk of cancer. Prolidase, adenosine deaminase, glutathione reductase and glutathione s-transferase enzyme activities may play an important role in the etiopathogenesis of pancreatic cancer.