Browsing by Author "Geçmen, Çetin"

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Early Qtc Interval Prolongation After Primary Percutaneous Coronary Intervention May Have a Positive Impact
(2021) Bilge, Önder; Karagöz, Ali; Erdogan, Emrah; Işık, Ferhat; Geçmen, Çetin; Kaymaz, Cihangir; Özdemir, Nihal
Objectives: Corrected QT (QTc) interval is prolonged in acute myocardial infarction and begins to shorten after successful reperfusion. Data on the early change of QTc after reperfusion and the prognostic significance of this change are limited. We aimed to evaluate the change of QTc interval in the first hour following successful primary percutaneous coronary intervention (pPCI) in ST-elevation myocardial infarction (STEMI) patients and its relationship with reperfusion parameters such as myocardial blush grade (MBG) and ST-segment resolution (STR%). Materials and Methods: Patients who presented with the first STEMI episode and underwent successful pPCI were included in the study. After pPCI, MBG and STR% were calculated. QTc measurements were made from the electrocardiography (ECG) recorded at admission (Pre-pPCI QTc), 1 hour after pPCI (Post-pPCI QTc), and the 24th hour. Results: One hundred and five patients who had successful pPCI with adequate ECG data were enrolled in the study. The mean Pre-pPCI QTc was 409±34 ms, and the mean post-pPCI QTc was 427±32 ms. A statistically significant prolongation was observed in the QTc interval after pPCI (QTc-Change) [21 ms (-3, 37 interquartile range (IQR)), p<0.001]. The median STR was 71% (60-83 IQR), and the median MBG was 2 (1-3 IQR). In the multivariable linear regression analysis, a significant relationship was observed between QTc-Change with MBG and STR%Conclusion: It was found that the QTc interval continued to prolong somewhat in the early period after successful pPCI in STEMI patients, and this QTc-Change was significantly associated with reperfusion parameters such as MBG and STR%. STR% and MBG were higher in those with higher QTc-Change.
Early Systolic Lengthening Is Associated With Syntax Score in Patients With Non-St Acute Coronary Syndrome
(Kare Publ, 2024) Çap, Murat; Acar, Rezzan Deniz; Unkun, Tuba; Geçmen, Çetin; Kaymaz, Cihangir; Erdogan, Emrah; Bakal, Ruken
Background: Early systolic lengthening is a echocardiographic strain parameter previ- ously used to determine the lesion severity in patients with stable coronary artery dis- ease. In the present study, we aimed to evaluate the relationship between early systolic lengthening and anatomic SYNTAX score in troponin (−) and (+) groups among patients with non-ST-elevation acute coronary syndrome (ACS). Methods: A total of 95 patients diagnosed with non-ST-elevation ACS were included in the prospective, non-randomized, single-center study. The patients were categorized into 2 groups as troponin (+) and troponin (−). The patients were evaluated in terms of echocardiographic, clinical, and angiographic parameters. Results: The baseline characteristics, including age (58 ± 13 vs. 60 ± 10 respectively, P = .340), a history of hypertension (67.1% vs. 64%, respectively, P = .479), diabetes (28.6% vs. 32%, respectively, P = .467), global longitudinal strain (−14.37 ± 5.11 vs. −16.42 ± 3.93, respectively, P = .095), left ventricular ejection fraction (58.71 ± 8.73 vs. 57.20 ± 8.70, respectively, P = .263), and E/e’ (8.44 ± 2.13 vs. 8.33 ± 1.99, respectively, P = .785), were similar between troponin (+) and troponin (−) groups. Left ventricle end-systolic diam- eter (3.2 ± 0.78; 3.50 ± 0.74 vs. 3.2 ± 0.78, respectively, P = .031), left ventricle end-systolic volume (55.57 ± 32.17 vs. 38.28 ± 13.63, respectively, P = .013), left ventricle end-diastolic volume (115.31 ± 49.54 vs. 91.23 ± 20.57, respectively, P = .042), the rate of early systolic lengthening (65.7% vs. 28%, respectively, P = .001), the duration of early systolic lengthen- ing (24.02 ± 31 ms vs. 15.56 ± 30.19 ms, respectively, P = .009), and the SYNTAX score (16 ± 11 vs. 10 ± 10, respectively, P = .023) were higher in the troponin (+) group. Furthermore, a significant correlation was found between early systolic lengthening and SYNTAX score (r = 0.43, P < .001). Conclusion: The rate and duration of early systolic lengthening were higher in patients in the troponin (+) group. Early systolic lengthening is related to SYNTAX score in patients with non-ST-elevation ACS.