Browsing by Author "Gulek, B."

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The Effects of Radiotherapy on Arterial Diameters in Patients With High-Grade Glial Tumors Who Have Undergone Adjuvant Radiotherapy
(Wolters Kluwer Medknow Publications, 2023) Karaca, F.; Mentes, S.; Boga, Z.; Akkaya, H.; Keskin, S.; Gulek, B.
Background and Aims: Our purpose was to evaluate the M2 branch of the middle cerebral artery (MCA) in high-grade glial tumor patients who undergo adjuvant radiotherapy (RT). For this purpose, the diameter of the M2 branch was measured and evaluated by means of contrast-enhanced magnetic resonance imaging (CE-MRI) before and after RT. Post-radiotherapeutical measurements were made 1, 3, 5, and 7 months after the procedure; and vascular diameter alterations were evaluated.Materials and Methods: CE-MRI examinations were performed on the 32 patients enrolled in the study, who had undergone radiotherapy of the temporoparietal region. MRI examinations were performed prior to RT (RT0) and 1 (RT1), 3 (RT2), 5 (RT3), and 7 (RT4) months after RT. The M2 branch of the MCA was evaluated on MRI images, and the vessel diameter was measured in millimeters (mm), and then comparisons were made.Results: Statistically significant results were obtained during RT0-RT1, RT0-RT2, RT0-RT3, RT0-RT4, RT1-RT2, RT2-RT4, and RT3-RT4, and comparisons of the diameters of the M2 branch of the right MCA were performed (P < 0.05). When the same measurements and comparisons were made for the M2 branch of the left MCA, statistically significant results were found for the RT1-RT2, RT1-RT3, and RT1-RT4 comparisons (P < 0.05).Conclusion: Our study showed that the MCA M2 branch diminished in size following RT. This was demonstrated by means of CE-MRI controls performed up to 7 months after the completion of the RT procedures.
Magnetic Resonance Imaging Assessment of Rectal and Vascular Changes Following Radiotherapy in Prostate Cancer Patients
(Wolters Kluwer Medknow Publications, 2025) Karaca, F.; Keskin, S.; Mentes, S.; Akkaya, H.; Gulek, B.
Background and Aims:Radiotherapy is the preferred treatment method for early-stage prostate cancer. The objective of this study was to evaluate the alterations that take place in the vascular structures of non-operated prostate cancer patients following the administration of curative radiotherapy.Methods:In total, 102 male patients who underwent curative external radiotherapy for prostate cancer were included in the study. A contrast-enhanced magnetic resonance imaging (CE-MRI) examination was performed on these patients both prior to and 3 months after the radiotherapy sessions. CE-MRI images were evaluated based on the measurements performed for the internal and external diameters of the rectum and the diameters of the bilateral iliac and femoral arteries. All measurements were done by the utilization of the centimeter (cm) scale.Results:No statistically significant differences were found between the pre- and post-radiotherapeutic measurements of the rectal internal and external diameters, right and left external iliac artery diameters, right and left femoral artery diameters, Gleason scores, and total and free prostate-specific antigen (TPSA and FPSA) levels, in terms of pathological stagings. The mean values of the rectal external diameter, right external iliac artery diameter, and the right and left femoral artery diameters, together with the TPSA and FPSA levels, were found to have been diminished at measurements done 3 months after the radiotherapy (P = 0.001).Conclusion:Vessel and rectal lumens were found to have been narrowed following radiotherapy, on CE-MRI examinations performed 3 months after the radiotherapy sessions.
Radiologic Follow-Up of Vascular Structures in Gastric Cancer Patients Receiving Adjuvant Radiotherapy
(Wolters Kluwer Medknow Publications, 2025) Karaca, F.; Keskin, S.; Akkaya, H.; Mentes, S.; Altintas, S.; Bayhan, A. Z.; Gulek, B.
Background and Aim:This study aimed to examine the changes in vascular structures due to radiotherapy (RT) in patients who received adjuvant RT and chemotherapy with the diagnosis of gastric cancer.Materials and Methods:Thirty-three patients receive curative doses of adjuvant external RT. The changes in the diameters of the portal vein (PV) and celiac artery (CA) in mm in computed tomography were examined before RT (RT0) and 3 months after RT (RT1).Results:The RT1-PV value decreases by 0.31 mm when compared to the RT0 value (P < 0.05). Likewise, the CA measurements too showed a decrease by 0.24 mm, when the RT0 and RT1 values were compared.Conclusion:In this study, the measurements of the CA and PV in mm at time RT1 were smaller than their measurements at time RT0.