Browsing by Author "Gungordu Solgun, Derya"

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Development of 5,5′-Bi(1,10 Pvc Membrane Potentiometric Sensor for Silver Determination
(Wiley, 2025) Gungordu Solgun, Derya; Kaya, Nurcan; Saydan Kanberoglu, Gulsah; Agirtas, Mehmet Salih
In this study, the selectivity of the 5.5 '-bi(1,10-phenanthroline) Compound (1) against Ag+ ions as a chemical sensor was investigated by both absorption and potentiometric methods. First, a 1 x 10(-5) M solution of Compound (1) in acetonitrile was prepared. For the selectivity test, 1 x 10(-2) M solutions of metal ions in acetonitrile were prepared. UV-visible absorption measurements were performed by adding metal ions to a 5.5 '-bi(1,10-phenanthroline) compound at certain concentrations. Among the studied metal ions, it was found to be selective only against silver ions. In addition, solid-state contact polyvinylchloride (PVC) membrane electrodes prepared using 5.5 '-bi(1,10-phenanthroline) as an ionophore were found to be selective against Ag+ ions among other ions. The optimum membrane composition of the measurement was determined as 3% 5.5 '-bi(1,10-phenanthroline) + 32% PVC + 64% o-nitrophenyl octyl ether (o-NPOE) + 1% potassium tetrakis(4-chlorophenyl) borate (KTpClPB). The potentiometric properties of the silver selective electrode were determined as linear working range 1.0 x 10(-7)-1.0 x 10(-3) M, detection limit 1.0 x 10(-7) M, pH working range 3.23-9.08, and response time 3 s. Absorption and potentiometric methods confirm the selectivity towards silver ions. The IRC analysis of the silver-containing complex, performed using the DFT/B3LYP method with the LanL2DZ basis set, reveals an activation energy of approximately 0.002 Eh, with the transition state energy at -1.433173 Eh.
Metal Contained Phthalocyanines With 3,4-Dimethoxyphenethoxy Substituents: Their Anticancer, Antibacterial Activities and Their Inhibitory Effects on Some Metabolic Enzymes With Molecular Docking Studies
(Taylor & Francis inc, 2022) Taslimi, Parham; Turkan, Fikret; Gungordu Solgun, Derya; Aras, Abdulmelik; Erden, Yavuz; Celebioglu, Hasan Ufuk; Gulcin, Ilhami
The compounds (3-6) used in this study were re-synthesized in accordance with our previous study. The inhibitory effect of the complexes on some metabolic enzymes was examined and it was demonstrated that the enzymes inhibited by ligands and their complex molecules at micromolar level. The best Ki value for alpha-glycosidase enzyme was absorved 1.01 +/- 0.08 mu M for compound 6. The biological activity of ligand and metal complexes against enzymes was compared with molecular docking method. The enzymes used against ligand and metal complexes respectively: Achethylcholinesterase for ID 4M0E (AChE), butyrylcholinesterase for ID 5NN0 (BChE), alpha-glycosidase for ID 1XSI (alpha-Gly). ADME analysis was performed to examine the drug properties of the compounds (3-6). Besides, the anticancer properties of the complexes were studied. The doses of all compounds caused significant reductions in MCF-7 cell viability. The 3 and 5 compounds administered to PC-3 cells exhibited a more pronounced cytotoxic effect than the other two compounds (4 and 6). Furthermore, antibacterial activities of these compounds against Escherichia coli and Staphylococcus aureus were examined. Communicated by Ramaswamy H. Sarma
Photovoltaic Enhancement Using Green-Synthesized AgNPs and Phthalocyanine in DSSCs
(Springer, 2025) Ödemiş, Ömer; Gungordu Solgun, Derya; Özkartal, Abdullah; Aǧirtaş, Mehmet Salih
This study aims to improve the photovoltaic properties of phthalacyanines by additives that can be used as DSSC to produce economical materials for renewable energy. Therefore, silver nanoparticles (AgNPs) were successfully synthesized by green chemistry method using green husk of walnut (GHW). Additionally, a new axial silicon phthalocyanine was synthesized. The phytocomponent AgNPs were doped with our newly synthesized phthalocyanine and applied in dye-sensitized solar cells (DSSC) as a sensitizer. The power conversion efficiency of the prepared DSSC was investigated. The formation of AgNPs was confirmed by optical absorption at wavelength between 350 and 540 nm. XRD data confirmed that the average crystallite size of AgNPs was 46.17 nm. FTIR analyses identified the bio-components potentially responsible for silver nanoparticle formation. TEM analysis shows that there are nanoparticles with an average size of 36.15 nm. The success of environmentally friendly green synthesized AgNPs to activate the sensitizer in DSSCs indicates that silver nanoparticles can be effectively used in such applications. The conversion efficiency of the axial phthalocyanine compound was measured as 2.05. However, as a result of doping the phthalocyanine compound with AgNPs, it was measured as 2.63 and 2.81 at 1:1 and 1:2 ratios, respectively. This clearly reveals the effect of AgNPs. © 2025 Elsevier B.V., All rights reserved.