Browsing by Author "Kiroǧlu, A.F."

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The Effect of Omalizumab on Allergic Rhinitis Symptoms: A Comparative Study
(Yuzuncu Yil Üniversitesi Tıp Fakültesi, 2026) Ağırbaş, S.; Kiroǧlu, A.F.; Çetin, Y.S.; Erdem, M.Z.; Yalınkılıç, A.
Both Omalizumab and (Montelukast+Desloratadine) are effective treatments for allergic rhinitis. However, these treatments have not been compared clinically. Therefore, we aimed to compare their efficacy on allergic rhinitis symptoms. Between December 2018 and November 2019, 25 patients with both allergic rhinitis and chronic urticaria and 25 patients with allergic rhinitis alone were included in the study. Patients with both allergic rhinitis and chronic urticaria received Omalizumab (300 mg/month) (Omalizumab group), while patients with allergic rhinitis alone received (Montelukast+Desloratadine)/daily (Desloratadine group). In addition, both groups received fluticasone pr opionate nasal spray (100 mcg/day in each nostril). At baseline and after 8-10 weeks (follow-up), symptoms and quality of life were assessed. A visual analogue scale was used for the assessments. Compared to baseline, both groups showed significant symptomatic improvements at follow-up. When the change from baseline to follow-up was compared, the groups were similar in terms of nasal congestion, rhinorrhoea, sneezing and quality of life. However, Omalizumab group was superior to Desloratadine group in term s of eye itching (68.55±17.62 vs 55.46±20.42; p=0.010). In conclusion, Omalizumab is more effective than Montelukast plus Desloratadine for eye itching in allergic rhinitis. © 2026, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
A Forgotten Difficult Entity:ozena Report of Two Cases
(2010) Yuca, S.A.; Yuca, K.; Kiroǧlu, A.F.; Yakut, F.
Atrophic rhinitis or ozena is a chronic nasal disease characterized by progressive atrophy of the nasal mucosa and underlying bone, accompanied by the formation of foul smelling, thick, dry crusts in the greatly enlarged nasal cavities. Although the incidence of ozena is greatly diminished, it is still encountered rarely. The etiology of ozena still remains enigmatic but hereditary, infectious, developmental, endocrine and nutritional factors have been implicated. We describe two patients with endoscopical, clinical evidence and computed tomography findings of atrophic rhinitis along with a review of the current literature.