Browsing by Author "Ozakbas, Serkan"
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Conference Object Characterizing Pain in Neuromyelitis Optica Spectrum Disorder: Prevalence and Clinical Features(Sage Publications Ltd, 2025) Yesiloglu, Pervin; Ozdogar, Asiye Tuba; Unal, Gozde Deniz; Engenc, Veysel; Zengin, Ela; Cilingir, Vedat; Ozakbas, SerkanConference Object Chronic Pain in Multiple Sclerosis: a Two-Year Longitudinal Study(Sage Publications Ltd, 2023) Karakas, Hilal; Ozdogar, Asiye Tuba; Ozcelik, Sinem; Kahraman, Turhan; Ozakbas, SerkanConference Object Clinical Characteristics and Disease Progression in Multiple Sclerosis: A Comparison of Late Middle-Age Onset Vs Late Adulthood Onset(Sage Publications Ltd, 2025) Ozakbas, Serkan; Simsek, Yasemin; Caliskan, Can; Ozdogar, Asiye TubaConference Object Clinical Comparison of Early and Late Onset Multiple Sclerosis at Age 35: Implications for Disease Progression and Management(Sage Publications Ltd, 2024) Kaya, Ergi; Aslan, Taha; Ozdogar, Asiye Tuba; Alizada, Said; Ozakbas, SerkanConference Object Cognitive Impairment in Multiple Sclerosis: Comparing Dual-Task Performance, Anxiety, Depression and Disability(Sage Publications Ltd, 2023) Sagici, Ozge; Ozdogar, Asiye Tuba; Baba, Cavid; Ozakbas, SerkanConference Object Cognitive Impairment Is Associated With Chronic Neuropathic Pain(Sage Publications Ltd, 2023) Karakas, Hilal; Ozdogar, Asiye Tuba; Sagici, Ozge; Samadzade, Ulvi; Kahraman, Turhan; Ozakbas, SerkanConference Object Cognitive Profiles of Relapsing Multiple Sclerosis Patients With Progression Independent of Relapse Activity Versus Non-NEDA Status(Sage Publications Ltd, 2025) Alizada, Said; Ozdogar, Asiye Tuba; Samadzade, Ulvi; Caliskan, Can; Ozakbas, SerkanArticle Comparative Analysis of Cognitive and Physical Characteristics in Late-Onset, Adult-Onset and Early-Onset Multiple Sclerosis Patients(Elsevier Sci Ltd, 2024) Ozakbas, Serkan; Kaya, Ergi; Aslan, Taha; Ozdogar, Asiye Tuba; Baba, CavidBackground: Late-onset multiple sclerosis (LOMS or L; MS) and early-onset MS (EOMS or E) are less common, and their prognosis can be different. To characterize the demographic and clinical features, and clinical outcomes of LOMS and EOMS patients, comparing them to adult-onset MS (AOMS or A) patients. Methods: The study was conducted as a secondary analysis of a prospective study. The participants were divided into three groups according to age of MS onset: early onset (<18 years of age), adult-onset (20-40 years of age), and late-onset (>55 years of age). Demographic variables, oligoclonal bands, IgG index, and Expanded Disability Status Scale (EDSS) score in admission, first year, second year and current EDSS were evaluated. The Timed 25- Foot Walk Test (T25FW), Timed Up and Go (TUG), Multiple Sclerosis Walking Scale-12, Single Leg Standing Test, Activity-Specific Balance Confidence Scale, Nine-Hole Peg Test, Epworth Sleepiness Scale and Restless Legs Syndrome Severity Scale were performed. Appropriate statistical analysis was made. Results: A total of 658 pwMS was included in the study and divided into three groups: EOMS (n n = 117), AOMS (n n = 499), and LOMS (n n = 42). Statistically significant differences were determined between groups in terms of age [L (mean:59.86+5.45 +5.45 years-y-)> A (36.87+9.12 +9.12 y)> E (26.56 +8.85 y), p < 0.001], education level, current EDSS score (L L > E, p < 0.001), EDSS score in first admission, EDSS score in the first year, EDSS score in the second year (L L > A > E, p < 0.001), reached an EDSS score 6 (E E > L p = 0.001, E > A p = 0.015), disease duration (E E > A, E > L , mean E = 11.66+9.7 +9.7 y, A = 7.99+7.4 +7.4 y, L = 6.31+4.67 +4.67 y) time switching second-line treatment to the third line (E E > L p < 0.001, A > L p = 0.002, mean E = 171.73+83.29 +83.29 months-m-, A = 136.13+65.75 +65.75 m, L = 65.85 +45.96 m), number of relapses (A A > E > L , median E = 4.0, A = 3.0, L = 2.0), distribution of MS type and oligoclonal band types. Significant differences were found in T25FW and TUG. Post-hoc analysis showed that participants in the LOMS group have longer T25FW (mean L = 7.8 + 6.11, A = 6.25+5.09, +5.09, E = 5.72+3.13, +3.13, p = 0.011) and TUG (mean L = 11.01+5.53, +5.53, A = 9.57+8.04, +8.04, E = 8.38+5.51, +5.51, p = 0.007) times than the AOMS and EOMS groups. Conclusion: Our result revealed that individuals with LOMS face elevated disability levels and a heightened propensity to transition from first-line treatments to more advanced therapeutic interventions. LOMS have worse lower extremity functional status than AOMS and EOMS patient. Clinical evaluations and treatment choices require more attention in LOMS. However, according to the low number of LOMS in our cohort, these results were considered cautious, and more wide and multi-center studies must be designed.Conference Object Comparative Analysis of Disease Progression and Disability Accumulation Between Early Onset and Adult Onset Multiple Sclerosis Patients at a Decade Post-Diagnosis(Sage Publications Ltd, 2024) Aslan, Taha; Kaya, Ergi; Ozdogar, Asiye Tuba; Yapici, Nurbanu; Ozakbas, SerkanConference Object Comparative Analysis of Restless Legs Syndrome and Neuropathic Pain Impact on Walking and Balance in Multiple Sclerosis: Clinical and Radiographic Insights(Sage Publications Ltd, 2024) Ozdogar, Asiye Tuba; Kaya, Ergi; Ozcelik, Sinem; Unal, Gozde Deniz; Ozakbas, SerkanConference Object Comparison of Early-Onset and Very Early-Onset People With Multiple Sclerosis Based on Cognitive and Physical Assessments(Sage Publications Ltd, 2023) Kaya, Ergi; Ozdogar, Asiye Tuba; Karakas, Hilal; Sagici, Ozge; Ozakbas, SerkanConference Object Comparison of the Objective and Subjective Cognitive Fatigue During Relapse and Remission in Individuals With Multiple Sclerosis: Preliminary Results(Sage Publications Ltd, 2024) Ozakbas, Serkan; Yigit, Pinar; Kara, Irem; Samadzade, Ulvi; Ozdogar, Asiye TubaConference Object Comparison of Two Commonly Used Depression Questionnaires Based on Reflecting Physical and Cognitive Functions in People With Multiple Sclerosis(Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Sagici, Ozge; Aslan, Taha; Ozcelik, Sinem; Ozakbas, SerkanConference Object Correlation Between Lesion Loads and Cognitive, Social Cognitive, and Physical Measures in Persons With Multiple Sclerosis(Sage Publications Ltd, 2023) Aslan, Taha; Ozdogar, Asiye Tuba; Sagici, Ozge; Karakas, Hilal; Ozakbas, SerkanConference Object Determinants of Fatigue in People With Multiple Sclerosis: an Investigative Analysis(Sage Publications Ltd, 2024) Ozdogar, Asiye Tuba; Alizada, Said; Simsek, Yasemin; Ozakbas, SerkanConference Object Determinants of Postpartum Relapse in Multiple Sclerosis: a Comprehensive Analysis of Demographic and Clinical Factors(Sage Publications Ltd, 2024) Alizada, Said; Samadzade, Ulvi; Yapici, Nurbanu; Kaya, Ergi; Ozdogar, Asiye Tuba; Ozakbas, SerkanConference Object Development a Machine Learning Model To Prediction of Expanded Disability Status Scale in Multiple Sclerosis Patients(Sage Publications Ltd, 2024) Ozdogar, Asiye Tuba; Emec, Murat; Zengin, Ela; Ozcanhan, Mehmet Hilal; Ozakbas, SerkanConference Object Development of Restless Legs Syndrome Severity Prediction Models for People With Multiple Sclerosis Using Machine Learning(Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Emec, Murat; Dastan, Seda; Karakas, Hilal; Baba, Cavid; Ozcanhan, Mehmet Hilal; Ozakbas, SerkanConference Object Do Brand-Name and Generic-Brand Drugs of Dimethyl Fumarate Show Similar Efficacy and Safety Profiles in Relapsing-Remitting Multiple Sclerosis(Sage Publications Ltd, 2023) Kaya, Ergi; Sagici, Ozge; Ozdogar, Asiye Tuba; Ozcelik, Sinem; Ozakbas, SerkanConference Object The Effect of Cognitive Impairment on Six Spot Step Test Performance in People With Multiple Sclerosis(Sage Publications Ltd, 2023) Dastan, Seda; Sagici, Ozge; Ozdogar, Asiye Tuba; Kaya, Ergi; Ozakbas, Serkan
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