Browsing by Author "Raya, Maria"

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    Urethral Reconstruction Using Amniotic Membrane Allograft in Hereditary Androgen Insensitivity Syndrome: a Case Series
    (Oxford Univ Press, 2023) Mansour, Marah; Raya, Maria; Jrdy, Abd Alrahman; Sires, Abdoul Majid; Wardeh, Jad Alhaq; Alsbekhan, Almoataz Ballah; Alrebdawi, Khaled
    Partial androgen insensitivity syndrome is a rare X-linked disorder. While most cases are sporadic, familial cases are less frequent. The management of this syndrome follows a multidisciplinary approach involving hormone substitution, psychological counseling, and surgical procedures. We present a case series of three young siblings with familial partial androgen insensitivity syndrome who presented with a female phenotype. All of them were managed with hormonal treatment for 6 months followed by surgical reconstruction. The operative procedure involved phalloplasty and urethroplasty using amniotic membrane transplant, which is considered a novel technique in this group of patients. No intraoperative or postoperative complications were observed and good results were achieved within 2 years of follow-up.