Browsing by Author "Simsek, N."

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Age Related Distribution of Mast Cells in the Trachea and Lung of Chicken
(indian veterinary Journal, 2006) Karaca, T.; Yoruk, M.; Simsek, N.
The Banach Algebras Generated by Operators With One-Point Spectrum
(Springer, 2011) Seferoglu, H.; Simsek, N.
In this article, we present some results related to the structure of Banach algebras generated by operators with one-point spectrum.
The Effect of Royal Jelly on Cd3+, Cd5+, Cd45+ T-Cell and Cd68+ Cell Distribution in the Colon of Rats With Acetic Acid-Induced Colitis
(Elsevier Espana Slu, 2012) Karaca, T.; Simsek, N.; Uslu, S.; Kalkan, Y.; Can, I.; Kara, A.; Yoruk, M.
Background: Traditional medicines and health supplements have historically been used to treat many illnesses but most of them have not been evaluated objectively to prove their efficacy. We have been investigating the effects of royal jelly (RJ) supplements on acetic acid-induced colitis on the distribution of CD3(+), CD5(+), CD45(+) T-cell and CD68(+) cells in rats. Methods: The rats were divided into four equal groups: control group, royal jelly-treated (RJ - 150 mg kg(-1) body weight), acetic acid-treated (colitis) and acetic acid-treated (colitis) + royal jelly (CRJ - 150 mg kg(-1) body weight). Colitis was induced by intracolonic instillation of 4% acetic acid; the control group received physiological saline (10 mL kg(-1)). Colon samples were obtained under deep anaesthesia from animals in four groups. Tissues were fixed in 10% formalin neutral buffer solution for 24 h and embedded in paraffin. Results: The proliferative response of CD3(+) and CD45(+) T cells stimulated with colitis was affected by colitis treated with RJ. No differences were found in CD5(+) T cells and CD68(+) macrophages in the colitis treated with RJ. Conclusions: This study has shown that RJ has anti-inflammatory and cell regeneration effect in the colon of rats with acetic acid induced colitis. (c) 2011 SEICAP. Published by Elsevier Espana, S.L. All rights reserved.
Effects of the Spirulina Platensis and Panax Ginseng Oral Supplementation on Peripheral Blood Cells in Rats
(Ecole Nationale veterinaire Toulouse, 2007) Simsek, N.; Karadeniz, A.; Karaca, T.
The effects of Spirulina platensis and Panax ginseng dietary supplementations were analysed in 30 female adult Wistar albino rats divided in 3 equal groups. In the first and second groups, animals were treated with Spirulina platensis (300 mg/kg/day) and with Panax ginseng (400 mg/kg/day) respectively in drinking water for 30 days, whereas the third group served as control. Red Blood Cell (RBC) and White Blood Cell (WBC) counts, numeration of leukocyte types, Packed Cell Volume (PCV) and haemoglobin concentrations were determined by haemocytometric methods on blood samples collected on days 0, 15 and 30, and Mean Globular Volumes (MGV) and Mean Corpuscular Haemoglobin Concentrations (MCHC) were calculated. Populations of B and T lymphocytes were counted by the proportional to naphthyl acetate esterase (ANAE) staining method. Spirulina platensis and Panax ginseng treatments markedly stimulated the erythrocyte formation and the haemoglobin synthesis on day 30 and small erythrocytes (microcytosis) greatly loaded with haemoglobin (increases of MCHC) were obtained especially with Panax ginseng. Dramatic increases of WBC counts since the 15th day were also observed in both treated groups. In Spirulina- treated rats, the neutrophil count was enhanced precociously (since the 15(th) day). The overall lymphocyte population as well the T cell number has gradually augmented according to the treatment duration in all treated rats. Furthermore, Panax ginseng treatment has exhibited significant greater effects on lymphocyte and T cell counts than Spirulina platensis treatment. These results suggest that these 2 biomedicines positively interfere with bone marrow cellular production and with immune cellular response and may be useful as adjuvant treatment of anaemia or of immune deficiency.