Browsing by Author "Ugras, Seda"

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Assessing the Effectiveness of Anaerobic Threshold and Respiratory Compensation Point on Fat and Carbohydrate Oxidations During Exercise in Sedentary Males
(Mattioli 1885, 2020) Ugras, Seda; Algul, Sermin; Ozcelik, Oguz
Study Objectives: Anaerobic threshold (AT) and respiratory compensation point (RCP) are two important metabolic set points. We aimed to determine the effects of exercise intensity at AT and RCP on the balance of substrate oxidation rates. Methods: Eleven male participants performed an incremental exercise test to exhaustion on a cycle ergometer to estimate AT and RCP. Subsequently, we conducted three 30 minute constant load exercise tests at AT (W-AT), RCP (W-RCP) and 25% below AT (W-
Comparatively Evaluating the Effects of Exercising at the Anaerobic Threshold on Oxidative Stress and Serum Levels of Leptin, Nesfatin-1 and Irisin in Sedentary Male and Females
(Mattioli 1885, 2022) Ugras, Seda; Algul, Sermin; Ozdenk, Cagri
Study Objectives: Exercise has a great impact in increases of energy metabolism and imbalance of oxidant-antioxidant status. We aimed to analyse the association between exercise-induced oxidative stress and energy regulatory hormones of leptin, nesfatin-1 and irisin in sedentary male and female subjects. Methods:A total of 30 subjects (15 males and 15 females) performed an aerobic exercise approximately 45 min. Blood samples were taken at baseline and the end of the exercise. ELISA method was used to analyse parameters of leptin nesfatin-1, irisin, total oxidant status (TOS) and total antioxidant status (TAS). Result: Exercise caused a significant increase in levels of irisin and TOS but TAS level decreased. In addition, leptin and irisin levels increased significantly in females, but they did not change significantly in males. Conclusion: However, gender differences have a great impact on energy regulatory hormones which needed to be evaluated in further stud-ies. Energy regulatory hormones did not correlate with the change of TAS and TOS levels.
Evaluation of Aerobic Exercise Induced Metabolic Stress on Serum Asprosin Levels: Comparison of Fitness Status
(Mattioli 1885, 2021) Algul, Sermin; Deniz, Gulnihal; Alp, Hamit Hakan; Ugras, Seda; Ozcelik, Oguz
We comparatively evaluated effects of aerobic exercise performed morning and afternoon on asprosin levels in young trained, sedentary males. A total of fifty male subjects (trained n=25, sedentary n=25) participated in morning and afternoon aerobic running exercises to approximately 70% of the subject's maximal heart rate for about 45 min. Pre- and post-exercise venous blood samples were taken and analysed for asprosin using ELISA. Serum CK and MDA levels were determined by measuring with an autoanalysers and a HPLC, respectively. Asprosin, CK and MDA levels increased significantly at the end of both morning (p<0.05), and afternoon (p<0.05) exercises in the trained and sedentary group. At the end of the acute running exercise in the trained group in the morning, the asprosine, MDA and CK levels increased by 24%, 29% and 32%; while they increased by 24%, 30%, and 40% in the afternoon, respectively. In the sedentary group, asprosin, MDA and CK levels increased by 31%, 38% and 31% after the acute running exercise in the morning, while the asprosin, MDA and CK levels increased by 34%, 58% and 42% after the acute running exercise in the afternoon, respectively. Asprosin levels increased in all subjects in both aerobic exercise tests without correlating increase of MDA and CK. Altered asprosin levels could be related other factors rather than metabolic and muscular stress parameters.