Browsing by Author "Yetkin, Y"

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The Effect of the Thyroliberin on the Syntheses of the Β-Endorphin and Corticotropin
(Medimond S R L, 2003) Hazar, H; Yetkin, Y; Yetkin, A
The effect of thyroliberin on syntheses of beta-endorphin and corticotropin were studied on the cats under anesthesia (Nembutal(R): 40 mg/kg, iv) in blood plasma (BP) and cerebral-spinal fluid (CSF). The BP and CSF were withdrawn from jugular vein and thoracic region at the 3(rd) and 20(th) minutes before and after the giving of thyroliberin. Thyroliberin made no change on the level of beta-endorphin in every two medium. At the beginning plasma level was 47 3.3 p mol/L. After 3 and 20 minutes, they were found 42+/-8.2 and 45+/-10.5 p mol/L. In spinal fluid it was found 1.3+/-0.4 p mol/L. After thyroliberin, the levels were 1.8+/-0.4 and 1.8+/-0.5 p mol/L. In plasma, the level of the corticotrophin increased in %75+/-18 at 3 and 20 minutes, whereas in the spinal fluid, thyroliberin decreased the corticotrophin as well as %41+/-1.3 and %63+/-9.1.
Physical Properties of the Cerebral Hemispheres and Paw Preferences in Mongrel Cats: Sex-Related Differences
(Taylor & Francis Ltd, 2002) Yetkin, Y
This study was performed on 30 female and 18 male mongrel cats, of which 36 appeared to be right- and 12 left-pawed, respectively. The physical features of the brain hemispheres and the paw preferences in cats were investigated related to both functional and morphological asymmetry. Right-pawed cats were more prevalent, with scores ranging from + 60 to + 80%, as compared with the left-pawed ones scoring from -40 to -60%. However, females were found to be more right- pawed than males, but the differences were not considered significant (p >.05). After half-open ether anesthesia, the whole brain was excised by craniotomy under deep-anesthesia (Ketalar(R): 40-50 mg/kg). The brains excised were kept in formaldehyde (10%) for three days, and then the weight, volume, density, and the morphological dimensions of left and right hemispheres and whole brain bodies were measured. There were no significant sex-related differences in body weights and paw preferences; nor was there any relation among the weights, volumes, and lengths of right and left hemispheres in either sex. There was, however, a significant sex-related difference between the mean heights of the left hemispheres of both male and female cats (p <.05), which is expected to be on the right hemispheres. As for the total samples, the mean density of the left hemispheres exceeded that of the right hemispheres.
Quantitative Analysis of 1-Hyoscyamine in Hyoscyamus Reticulatus L. by Gc-Ms
(Tubitak Scientific & Technological Research Council Turkey, 2003) Kartal, M; Kurucu, S; Altun, L; Ceyhan, T; Sayar, E; Cevheroglu, S; Yetkin, Y
The hyoscyamine content of leaves and root samples of Hyoscyamus reticulatus L. from Bulamk, Mus in east Anatolia, Turkey, was determined by capillary GC-MIS to be 0.036 +/- 0.004% in the leaves and 0.056 +/- 0.011% in the roots as the predominant compound. Sopolamine was only detected in trace amounts. These findings are in accordance with reports on hyoscyamine content in Hyoscyamus species. The limit of detection was 3.125 mug/mL and the limit of quantification was 6.25 mug/ml, for hyoscyamine. This method has been shown to be linear and sensitive.