TR-Dizin İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14720/5

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1800 Mhz Radio-Frequency Electromagnetic Radiation Induces Oxidative Stress in Rat Liver, Kidney and Brain Tissues
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Berköz, M.; Arslan, B.; Yıldırım, M.; Aras, N.; Yalın, S.; Çömelekoğlu, Ü.
Radio-frequency electromagnetic radiation (RF-EMR) represents one of the environmental factor that influence animal organism to stress. In this study we determined the oxidative stress parameters from rat liver, kidney and brain tissues that were exposed to chronic 1800 MHz RF-EMR. Our study was designed in 3 groups as 9 animals in each group. These are; control, sham and RF-EMR exposed group. The control group was not exposed to any procedure; sham group was housed in the same room under the same conditions with equal time period, except that the generator was turned off. RF-EMR exposed group was subjected to 1800 MHz RF-EMR emitted from the signal generator for 2 h per day for eight weeks. All animals that completed the experimental period were sacrificed and liver, kidney and brain tissues of all rats were isolated for analyzing malondialdehyde (MDA), nitric oxide (NO) and reduced glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activities. Liver, kidney and brain MDA and NO levels were higher and GSH level and SOD and catalase activities were significantly lower in RF-exposed group than control and sham groups (p<0.001). No significant difference was observed in terms of tissue MDA, GSH and NO levels and SOD and catalase activities between control and sham groups in each tissue. The results of our study shows that RF-EMR may act as an environmental stressor and cause oxidative and nitrosative damage in liver, kidney and brain tissues. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
3d Location Optimization of Multiple Unmanned Aerial Vehicle Base Stations in Next-Generation Cellular Networks and a New Meta-Heuristic Approach
(Gazi Univ, Fac Engineering Architecture, 2021) Ozdag, Recep
The use of Unmanned Aerial Vehicles (UAVs) as mobile Base Stations (BSs) in wireless communication is emerging as an effective technique that should be used for the services planned in the next-generation cellular networks or in disaster situations. Currently, effective 3D placement of BS mounted on UAVs or Drones (Drone-BS), also called Low-altitude Air Platforms, in the defined area significantly increases the Quality of Service (QoS) of wireless communication. This study has been aimed to be performed dynamic deployments (location optimization) of Drone-BSs randomly distributed in the 3D plane in order to optimally cover the users in the urban environment according to the Air-to-Ground (ATG) model. Using new approaches based on the Electromagnetism-Like (EML) Algorithm and the Whale Optimization Algorithm (WOA), which are widely used in the literature and are meta-heuristic, it was planned to be covered the maximum number of users on the ground by multiple Drone-BSs. In addition, Extensive-interval Optimal Fitness Search Algorithm (EOFSA-EML) and Discrete-interval Optimal Fitness Search Algorithm (DOFSA-EML) approaches were developed based on the EML algorithm. Based on comparison metrics for multiple Drone-BSs distributed by EOFSA-EML, DOFSA-EML, and Pure-WOA, it has been found that EML-based algorithms achieve optimal results compared to Pure-WOA.
Ab Initio Study of Li2cata2o7 Compound: Electronic and Optical Properties for Three Phases
(Tubitak Scientific & Technological Research Council Turkey, 2019) Aycibin, Murat
The Li2CaTa2O7 compound belongs to the Ruddlesden-Popper family of layered perovskites. First principle approximation was used to investigate the electronic band structure and optical properties of the compound for three phases. Independent of the studied compound's structural type, Li2CaTa2O7 has semiconductor behavior and direct transition. In addition, the forbidden energy band gap of the compound decreases with rising temperature, as expected. Furthermore, the 3d orbital of Ca contributes to the conduction band due to the crystal field effect. Moreover, the optical response of the chosen axes of the compound to incoming electromagnetic rays varies with phase transition.
Abc, Ved, and Abc-Ved Matrix Analyses for Inventory Management in Community Pharmacies: a Case Study
(Society of Pharmaceutical Sciences of Ankara (FABAD), 2022) Dursa, E.; Arslan, M.
Inventory control methods should be used effectively in community pharmacies to determine and obtain the needs for pharmaceuticals and non-pharmaceutical products at appropriate times and with proper procedures. An effective stock control provides positive outputs in the community pharmacy’s economy, the quality of the service to be provided, and the pharmacy’s image. In this context, within the scope of this study, it aims to evaluate ABC, VED, and ABC-VED matrix analyses in terms of community pharmacies. In the study, ABC, VED, and ABC-VED matrix analyzes were applied using the inventory data of a community pharmacy serving in the city center of Van for the 2019-2020 financial year. For this purpose, firstly, annual consumption and expenditure data for each pharmacy item specified for the 2019-2020 financial year were collected. The data were then transferred to an MS Excel spreadsheet, and statistical analysis was performed using MS Excel statistical functions. As a result of ABC-VED analysis, it was determined that the drugs in the first category were of great importance for effective stock control, the drugs in the second category were of medium importance, and the drugs in the third category were of low importance. They are because the pharmacy from which the research data is taken is close to the family health center and the socioeconomic structure of the pharmacy’s environment. This categorization is thought to be appropriate. © 2022 Society of Pharmaceutical Sciences of Ankara (FABAD). All rights reserved.
Abo and Rh Blood Groups Frequency in Men and Women Living in Eastern Turkey
(2006) Dilek, I.; Demir, C.; Bay, A.; Akdeniz, H.; Öner, A.F.
Objective: ABO and Rh blood groups which are basic for determination of blood compatibility consist of the most important tests of blood center. In this study, we aimed to find out the rates of ABO and Rh blood groups in male and female donors in our region. Therefore, donors attending to our blood center within the last five years were investigated taken into account their gender. Methods: Blood groups were examined by gel-centrifugation or tube agglutination methods. Results: Out of totally 33.193 individuals, 14.716 were female (44.3%) and 18.477 males (55.7%), and average age was 34 (range 20-60 years old). Taken into account the whole donors, A blood type was found as 43.8%, O blood type 30.8%, B blood type 16.2% and AB blood type 8.6% in rate. With respect to blood type frequency in genders group A was in the rate of 44.1% and 43.6%, group O 31% and 30.5%, group B 16.3% and 16.1% and group AB 8.6% and 9.8% in women and men, respectively. The Rh positivity rate into totally whole donors was 85.5%, being 86.0% in men and 84.8% in women. Conclusion: ABO and Rh blood groups rates were very near to each other in women and men, and also the average rate was very similar to averages in Turkey.
Accessibility Analysis of Urban Green Space: the Case of Erbil City
(Konya Technical Univ, Fac Architecture & design, 2023) Kemec, Serkan; Abdalkarim, Salar Hassan
Urban green areas are open spaces in urban areas that are mainly covered by vegetation. They can be public or private urban green spaces that include parks, community gardens, forests, and nature reserves. Parks are an important component of urban quality of life if they are well designed and accessible. Accessible parks contribute to physical activity among urban residents. Therefore, the objective of the study was to identify the most significant main accessibility factors that discourage the use of public urban green areas, and examine the extent to which they influence the use of green areas in residential areas of the city of Erbil. This study was conducted in 2017 and 2020 to measure the accessibility of green spaces using network analysis with GIS for Erbil city. The present study represents the first known investigation regarding the accessibility of public green spaces within the city of Erbil. The results show that for community parks, 68% of the population has access with a travel time of 5 minutes, 99% of the population has access with a travel time of 10 minutes, and 100% of the population has access with a travel time of 15 minutes. For district parks, 70% of the population had access with 5 minute drive time. With 10-minute drive time, 96% of the population had access and 100% of the population had access with 15-minute drive time. For neighborhood parks, the results show that 43% of the population had access with 5-minute walk and, 71% of the population had access with 10-minute walk. At 15-minute walk time, 80% of Erbil residents had access to neighborhood parks. Mini parks were accessed by 22% of the population with a 5 minute walk and they were accessed by 52% of the population with a 10 minute walk. With a 15 minute walk, mini parks were accessible to 70% of the population.
Actions of Resveratrol and Serotonin Added To Stored Bloods on Lipid Peroxidation and Oxidative Dna Damage
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Huyut, Z.; Şekeroğlu, M.R.; Alp, H.H.; Balahoroğlu, R.; Çokluk, E.
Stored blood for use in diseases such as acute blood loss, injury and anemia can be maintained for about a month. It was reported that some negative changes called "storage lesions" occur in stored bloods time dependently. In order to delay these changes, preservatives are added to stored bloods. In this study, we aimed to determine the effects of resveratrol and serotonin on oxidative DNA and mitochondrial damage and lipid peroxidation in stored blood. Blood was taken from 10 volunteers to different blood bags and each blood was separated into 3 groups (control, resveratrol and serotonin groups). Malondialdehyde (MDA), ubiquinone-10 (CoQ10) and 8-hydroxy-2-deoxyguanosine/106deoxyguanosine (8-OHdG/106dG) levels were determined at baseline and on the 7th, 14th, 21st and 28th day after addition of resveratrol and serotonin. MDA, CoQ10 and 8-OHdG/106dG levels increased over time in the control and serotonin groups (p<0.05). However, resveratrol protected against the time-dependent increase in MDA and CoQ10 values (p>0.05). MDA and CoQ10 levels were significantly lower in the resveratrol-treated group on the 21st and 28th days compared with the other groups (p<0.05). These results show that oxidation sensitivity increased time dependently in stored blood. However, the addition of resveratrol allowed the extension of the blood’s shelf life by protecting against increased lipid peroxidation and oxidized CoQ10. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Active Tectonic Setting and Paleoseismicity of the Sancak-Uzunpazar Fault Zone
(Afet ve Acil Durum Yonetimi Baskanligi (AFAD), 2021) Selcuk, A.S.; Erturac, M.K.; Karabacak, V.; Sancar, T.; Kul, A.O.; Yavuz, M.A.
Sancak-Uzunpazar Fault Zone is N40E-trending sinistral shear zone that has a 50 km length and 5 km width between Karakocan (Elazığ) in southwest and Kaynarpınar (Bingöl) in northeast. The fault extends parallelly to East Anatolian Fault is bounded by the North Anatolian Fault to the northeast and Karakoçan Fault to the southeast. Herein, morphological features, the tectonic setting of the Sancak-Uzunpazar Fault Zone and the first paleoseismological studies on it is represented. The Sancak-Uzunpazar Fault Zone is consist of two parallel segments (called East and West) with a 1.5 km distance. Conducted field studies and aerial photogrometry show that the segments exhibit morphological features like faceted surfaces, faulted scarps, shutter ridges, and offset streams. Especially, average offsets are about 7-12 m along the eastern segment while the cumulative maximum offset reaches 1.1 km. Moreover, revealed paleoseismological data show evidence of at least two surface ruptures during Holocene. Obtained morphological data reveal that the Sancak-Uzunpazar Fault Zone may have a relatively lower slip rate when compared to other active faults in the region and the reflection of the slip rate to the morphology is more evident in the eastern segment. © 2022 Turk Deprem Arastirma Dergisi. All rights reserved.
The Activities of Gst Isozymes in Stomach Tissues of Female Obese Patients
(Walter de Gruyter Gmbh, 2020) Yilmaz, Can; Bulus, Hakan; Oguztuzun, Serpil; Cihan, Mehmethan; Fidan, Ceylan
Objectives: Obesity has become an important public health problem because of its increasing prevalence and relation with many diseases and mortality. Studies have shown its association with oxidative stress. In this study, the effect of obesity on total amount of thiol and some glutathione S-transferase (GST) isozymes were investigated which could serve as an important criteria in dose adjustment of some certain drugs in obese. Methods: The gastric tissues removed by gastrectomy operation from 29 morbid obese female patients were analysed for thiol levels and activities of total GST, GSTT1-1 and GSTM1-1. Patients were grouped according to age, presence of hypertension and/or diabetes, and family history. Results: The average total thiol was 131.22 (+/- 7.74) nmol/mg protein with no significant differences in between the groups. GSTT1 specific activities were about 20% higher in four groups: with ages over 35 years old, with hypertension, without diabetes and finally without family history, with respect to other groups. The differences between total GST and GSTM1 activity levels of experimental groups were not significant. Conclusions: This is the first study to compare activities of GST isozymes and total thiol content in the stomach tissues of obese female patients accompanying some common metabolic disorders, age and family history.
Acute Effects of Trichloroacetic Acid on Serum Enzyme Levels and Erythrocyte Carbonic Anhydrase Activity in Rats
(2006) Demir, H.; Çelik, I.
The aim of the present study was to investigate the effects of a sublethal dose of trichloroacetic acid (TCA) on serum enzyme levels and erythrocyte carbonic anhydrase (CA) activity in rats under laboratory conditions. Ten Sprague-Dawley albino rats were divided in 2 groups of 5 rats. A 200 mg/kg dose of TCA was administered intraperitoneally to the 5 rats in the treatment group. An equal amount of saline solution was injected into the control group. Serum enzyme levels and erythrocyte CA activity of the rats were measured 1, 3, and 6 h after treatment. According to the results, while the TCA sublethal dose treatment caused significant increases in lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) after 1 and 3 h, aspartate aminotransferase (AST) significantly increased after 1, 3, and 6 h. No significant differences in the levels of alanine aminotransferase (ALT) and erythrocyte CA were observed in comparison to the controls. It was concluded that TCA may cause toxicity in rats. © TÜBİTAK.
Acute Myeloblastic Leukemia-Associated Marfan Syndrome and Davidoff-Dyke Syndrome: a Case Report
(2008) Demir, C.; Bay, A.; Dilek, I.; Öner, A.F.
We present herein a 23-year-old man with acute myeloblastic leukemia (AML) associated with Davidoff-Dyke-Masson syndrome (DDMS) and Marfan syndrome (MS). The diagnosis of DDMS was based on findings including left facial asymmetry, left hemiparesis, mental retardation, right cerebral hemiatrophy, dilatation of the ipsilateral lateral ventricle and calvarial thickening. The diagnosis of MS was based on clinical findings including tall stature, myopia, retinitis pigmentosa, blue scleras, scoliosis, pectus excavatum, arachnodactyly and low ratio of upper/lower body segment. The patient developed hepatosplenomegaly, gingival hypertrophy and pancytopenia. Peripheral blood film and bone marrow examination showed that most of nucleated cells were blasts; immunophenotype of those cells showed CD11+, CD13+, CD14+, CD33+ and HLA-DR+. These findings confirmed the diagnosis of AML (FAB-M5). After induction chemotherapy, remission was obtained. To the best of our knowledge, our case is the third report of AML in MS syndrome, while AML associated with DDMS and MS has not been previously reported in the literature.
Acute Rupture of a Congenital Sinus of Valsalva Aneurysm After Severe Exercise
(Turkish Soc Cardiology, 2009) Tuncer, Mustafa; Eryonucu, Beyhan; Guntekin, Unal; Gumrukcuoglu, Hasan Ali
Ruptured aneurysms of the sinus of Valsalva may cause manifestations of prompt onset. A 22-year-old man with no previous cardiac complaints presented with dyspnea, palpitation, fatigue, and shortness of breath, all of which occurred after a football match. Transthoracic echocardiography showed an aneurysmal dilatation of the right sinus of Valsalva to the direction of the right ventricle. Color Doppler imaging showed a marked left-to-right turbulent flow from the aortic root to the right ventricle. Continuous Doppler imaging also revealed a continuous left-to-right systolodiastolic shunting. The patient was submitted to cardiovascular surgery for surgical repair.
Acute Segmental Testicular Infarction Caused by Covid-19 Disease: a Case Report and Current Literature Review
(Galenos Yayincilik, 2022) Demir, Murat; Dundar, Ilyas
Coronavirus disease-2019 (COVID-19) is known to cause sepsis-associated hypercoagulopathy. Thromboembolic complications affecting many systems associated with COVID-19 disease have been described in the literature. The direct effect of this virus on male urogenital organs and possible testicular damage is still being evaluated. Follow-up studies in recovering male patients are necessary to investigate the possibility of testicular damage. In this article, we aimed to present a 30-year-old patient who presented with acute testicular pain and was diagnosed with testicular infarction due to COVID-19 with ultrasonography and contrast-enhanced magnetic resonance imaging findings.
Acute Stroke Management in Türkiye: Intravenous Tissue Plasminogen Activator and Thrombectomy Nörotek: Türkiye Neurology Single Day Study
(Galenos Publ House, 2023) Topcuoglu, Mehmet Akif; Ozdemir, Atilla Ozcan; Arsava, Ethem Murat; Gunes, Aygul; Aykac, Özlem; Gencer, Elif Sarionder; Ozturk, Serefnur
Objective: To reveal the profile and practice in patients with acute stroke who received intravenous tissue plasminogen activator (IV tPA) and/or neurointerventional therapy in Turkiye. Materials and Methods: On World Stroke Awareness Day, May 10, 2018, 1,790 patients hospitalized in 87 neurology units spread over 30 health regions were evaluated retrospectively and prospectively. Results: Intravenous tPA was administered to 12% of 859 cases of acute ischemic stroke in 45 units participating in the study. In the same period, 8.3% of the cases received neurointerventional treatment. The rate of good prognosis [modified Rankin score (mRS) 0-2] at discharge was 46% in 83 patients who received only IV tPA [age: 67 +/- 12 years; National Institutes of Health Stroke Scale (NIHSS): 12 +/- 6; hospital stay, 24 +/- 29 days]; 35% in 51 patients who underwent thrombectomy (MT) alone (age: 64 +/- 13 years; NIHSS: 14.1 +/- 6.5; length of hospital stay, 33 +/- 31 days), 19% in those who received combined treatment (age: 66 +/- 14 years; NIHSS: 15.6 +/- 5.4; length of hospital stay, 26 +/- 35 days), and 56% of 695 patients who did not receive treatment for revascularization (age: 70 +/- 13 years; NIHSS: 7.6 +/- 7.2; length of hospital stay, 21 +/- 28 days). The symptom-to-door time was 87 +/- 53 minutes in the IV treatment group and 200 +/- 26 minutes in the neurointerventional group. The average door-to-needle time was 66 +/- 49 minutes in the IV tPA group. In the neurothrombectomy group, the door-to-groin time was 103 +/- 90 minutes, and the TICI 2b-3 rate was 70.3%. In 103 patients who received IV tPA, the discharge mRS 0-2 was 41%, while the rate of mRS 0-1 was 28%. In 71 patients who underwent neurothrombectomy, the mRS 0-2 was 31% and mRS 0-1 was 18%. The door-to-groin time was approximately 30 minutes longer if IV tPA was received (125 +/- 107 and 95 +/- 83 minutes, respectively). Symptomatic bleeding rates were 4.8% in IV recipients, 17.6% among those who received only MT, and 15% in combined therapy. Globally, the hemorrhage rate was 6.8% in patients receiving IV tPA and 16.9% in MT. Conclusion: IV thrombolytic and neurointerventional treatment applications in acute ischemic stroke in Turkiye can provide the anticipated results. Heterogeneity has begun to be reduced in our country with the dissemination of the system indicated by the "Directive on Health Services to be Provided to Patients with Acute Stroke."
An Adaptation Study of the Balanced Measure of Psychological Needs (Bmpn) Scale To Turkish Culture
(Cukurova Univ, 2018) Kardas, Ferhat; Yalcin, Ilhan
Psychological needs have long been one of the most widely studied topics in the field of mental health. One of the commonly used approaches in recent years in psychological needs satisfaction research is self-determination theory. It is stated in the frame of self-determination theory that psychological needs are universal and can be classified as needs in terms of competence, relationship and autonomy. The aim of this study is to adapt the Balanced Measure of Psychological Needs (BMPN) Scale, which was developed to measure the satisfaction level within the framework of self-determination theory, to Turkish culture. After examining the related literature, a validity and reliability study of the BMPN Scale has been carried out on the students of the Faculty of Educational Sciences of Ankara University, and on the pedagogical formation students from other faculties. Confirmatory factor analysis in the study was conducted on 285 students, criterion related validity on 282 and test re-test reliability on 50 students. 80.5% of the respondents were female and 19.5% were male. The average age of participants was 22. As a result of the research, it was determined that the psychometric properties of the scale were adequate, and the model fit values were appropriate. Accordingly, the Turkish form of BMPN was considered a valid and reliable measurement tool that can be used in research on needs satisfaction.
Adsorption of Acid Blue 25 on Peach Seed Powder: Isotherm, Kinetic and Thermodynamic Studies
(Yildiz Technical University, 2019) Kul, A.R.; Aldemir, A.; Elik, H.
In the present study peach seed powder (PSP) was used as an adsorbent to remove Acid Blue 25 (AB25) a common basic dye, from aqueous solution. The adsorption experiments were carried out in a batch system and the effects of initial concentration, interaction time and temperature were investigated. The Langmuir, Freundlich and Temkin adsorption isotherms were used to model the equilibrium data. The kinetic parameters were determined by the pseudo first order (PFO), pseudo second order (PSO) and intra-particle diffusion (IPD) models. According to the results, the Freundlich isotherm model is a more convenient option compared with the Langmuir and Temkin models. The Freundlich model coefficients increased as the temperature increased, which shows that the adsorption process becomes more favorable with higher temperature. The experimental and calculated qe values close to one another indicated that this process fits the PSO kinetic model with higher R2 values than the other two models. Kinetic constants become closer to both the temperatures and initial concentrations and qe values increases with the increasing concentration of AB25. The initial dye concentration increased from 25 to 150 mg L-1, while the dye adsorption capacity onto PSP increased from 4.80 to 39.01 mg g-1, from 5.57 to 44.27 mg g-1 and from 6.80 to 49.22 mg g-1 for 298, 308 and 323 K, respectively. The monolayer adsorption capacity (qm) of PSP was determined to be 56.18, 64.94, 95.24 mg g-1 for 298, 308 and 323 K, respectively. Thermodynamic parameters for free energy (ΔG), enthalpy (ΔH) and entropy (ΔS) of the separation process were determined as -1737,1 J mol-1, 14.776 kJ mol-1 and 55,413 J mol-1, respectively. The negative values of ΔGo showed that this separation process was endothermic and natural. The results of the present study demonstrated that PSP can be used as an alternative material in dye removal. © 2023 Bulletin of Monetary Economics and Banking.
Adsorption of Basic Blue 41 Using Juniperus Excelsa: Isotherm, Kinetics and Thermodynamics Studies
(Yildiz Technical University, 2019) Kul, A.R.; Aldemir, A.; Alkan, S.; Elik, H.; Caliskan, M.
In this study Juniperus excelsa shavings powder (JESP) was utilized as an adsorbent for the removal of Basic Blue 41 (BB 41) which is one of the common basic dyes, from aqueous solution. The adsorption experiments were carried out in a batch system and effects of initial concentration of dye, interaction time and temperature were investigated. Langmuir, Freundlich and Temkin adsorption isotherms were used to model equilibrium data. According to the results, Freundlich isotherm model becomes more convenient option compared with Langmuir and Temkin models. Freundlich model coefficients are raise as the temperature rises, showing that the adsorption process becomes favorable higher temperature. The kinetic parameters were determined by pseudo first order (PFO), pseudo second order (PSO) and intra-particle diffusion (IPD) models. Results indicated that experimental and calculated qe values are matched to each other. Thus the process fits PSO kinetic model with higher R2 values than other two models. Kinetic constants become closer to both temperatures and initial concentrations and qe values are increases with increasing concentration of BB 41. Initial dye concentration elevates from 25 to 100 mg L-1, dye adsorption capacity onto JESP from 3.06 to 16.53 mg g-1, respectively. Thermodynamic parameters for instance free energy (ΔG), enthalpy (ΔH) and entropy (ΔS) were assessed. Enthalpy and entropy of this separation process are determined from 3081.91 J mol-1 and 12.33 kJ mol-1, respectively. The negative values of ΔG° showed that this separation process was endothermic and natural. The research results demonstrate that JESP may be a substitute than pricey adsorbents for dye removal. © 2019 Yildiz Technical University. All rights reserved.
Adult Patient Cancer Statistics of Mardin Province
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Aytekin, A.
Some types of cancer are more common in some regions. The data in Turkey are recorded with the cancer registry system but this data does not cover all cities. This study aimed to investigate the clinical and demographic characteristics of oncology patients admitted to Mardin State Hospital. The records of patients, who admitted to Mardin State Hospital Medical Oncology Clinic between 2014-2018, were retrospectively reviewed. Patients over 18 years of age were included in the study. Gender, diagnosis and disease stages of the patients were recorded. The median age of the 1208 patients (654 female and 554 male) was 57 (18-94) years. The median age was 52.25 in women and 60.92 in men. The 5 most common cancers in the whole group were; breast cancer, colorectal cancer, lung cancer, prostate cancer and gastric cancer, respectively. In men; the most common types of cancer were; lung, colorectal, prostate, head-neck and gastric cancer. On the other hand in women, the most common types of cancer were breast, colorectal, ovarian, gastric and uterus corpus cancer. The most common presentation stage was stage 4 (n = 416, 34.4%) in the whole group, stage 2 (n = 204, 31.2%) in women and stage 4 (n = 253, 45.7%) in men. Adenocarcinoma was the most common histologic type in both the male and the whole group (female and male) of patients. The most common histological types in women was breast carcinomas (invasive lobular and ductal carcinomas). In this study, the incidence of colorectal cancer in all groups (men, women and total) was higher in Mardin province when compared with Turkey data. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Advances in Current Medication and New Therapeutic Approaches in Epilepsy
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Allahverdiyev, O.; Dzhafar, S.; Berköz, M.; Yıldırım, M.
Epilepsy is one of the most complicated neurological disorders associated with a brain disorder in which, after an in itial physiological insult, the networks of neurons regroup and communicate abnormally that can be defined as the neuronal hyper -synchronizayion. The affected part of brain defines the patient’s abnormality behavior. Unlike the younger patients, who can become seizure free after the age of 16-18, older patients are hardly able to overcome the seizures, especially once the type of seizure developed to generalize tonic-clonic phase. Globally, epilepsy is considered as a disease which is originated from the disorder of electrical function of the brain and estimated to effect approximately 50 million people worldwide. Pharmacoresistance, drug interactions, drug tolerability and various adverse effects are among the common problems associated with the treatments of epilepsy with antiepileptic drugs (AEDs). Although, approximately 70% of the patients exhibit seizures that can be controlled with most AEDs, the remaining 30% of the patients fail to respond to treatment with AEDs. Thus, looking for alternatives such as traditional treatment methods like utilizing medicinal plants, ketogenic diet, and the Atkins diet as well as self-physical therapy like relaxation and yoga, are all positive options that can be considered as replacement and supportive therapy methods for the medications which are used in seizure control of epilepsy. Medicinal plants are more commonly used by folk for making infusions administered as herbal teas for the pain relief and maintaining good health. Investigating the active components of a plant extract, isolating and identifying their structure and pharmacological effects, and finally utilizing them as a new agent from nature with fewer side effects and high economic valu e is a widely interested topic in the field of ethnoparmacology. In addition to AEDs, which are currently used, the suggested alternative therapies are also able minimize the seizures of epilepsy but the surgical intervention still remains as the last option in the treatment of epilepsy. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Age-Stage, Two-Sex Life Table: the Basis of Population Ecology, Biological Control and Pest Management
(Centenary University, 2018) Atlihan, R.; Özgökçe, M.S.; Chi, H.
Because they are capable of providing an integrated and comprehensive description of numerous biological parameters (survival, development, fecundity, etc.) of a population, life tables are one of the most powerful tools available for biologists and other researchers conducting research on population ecology, biological control, and pest management. Since the traditional female age-specific life tables ignore the male population and stage differentiation, their use often results in errors and inaccuracies. This article was prepared to discuss the reasons and advantages of using the age-stage, two-sex life table. © 2018, Centenary University. All rights reserved.

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