TR-Dizin İndeksli Yayınlar Koleksiyonu

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12 Kasım 1999 Düzce Depremi Artçı Depremlerinden Hesaplanan B ve P Değerlerinin Uzaysal ve Zamansal Dağılımı ve Gelecekteki Sismik Tehlike Açısından Değerlendirmeler
(2005) Alptekin, Ömer; Utkucu, Murat; Çetin, Canan
Gerek laboratuvar, gerekse gerçek deprem verilerini esas alan çalışmalardan deprem istatistiğinin frekans-büyüklük bağıntısındaki b değerinin yerkabuğundaki gerilim ile ters orantılı olduğu anlaşılmıştır. Bu çalışmada; 12 Kasım 1999 Düzce depreminin artçı deprem verilerinden bu depremin kırılma düzlemi ve bitişiğindeki Karadere ve Elmalık fay segmentleri boyunca yüzeyde ve derinlik boyutunda b değerleri ve artçı deprem azalım sabiti p'nin uzaysal dağılımı bir bilgisayar paket programı kullanılarak hesaplanmıştır. Düzce depremi için, Düzce fay segmenti üzerindeki pürüz boyunca haritalanan b=1.2-1.5 ve p=1-1.3 değerleri daha yüksek iken, Karadere (b=0.8-1.0, p=0.7-0.8) ve Elmalık (b=1.1-1.2, p=1.1) fay segmentleri boyunca daha düşük b değerleri elde edilmiştir. Ayrıca, b değerlerinin özellikle Düzce fayı üzerinde 1999 Düzce depremi öncesine göre yükseldiği görülmüştür. Bu durum, Karadere ve Elmalık fay segmentleri boyunca Düzce depremi sonrasında gerilme artışları (Düzce fayı üzerinde ise gerilme azalımı) olduğunu düşündürmektedir. Karadere fay segmentinin 17 Ağustos 1999 Kocaeli depremi sırasında kırılmış olması ve Elmalık fay segmenti üzerinde geçen yüzyıl içinde kaydadeğer bir deprem olduğuna ilişkin veri olmaması, 1999 Düzce depremi sonrasında bu fay üzerinde deprem tehlikesinin arttığı şeklinde yorumlanmıştır.
1800 Mhz Radio-Frequency Electromagnetic Radiation Induces Oxidative Stress in Rat Liver, Kidney and Brain Tissues
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Berköz, M.; Arslan, B.; Yıldırım, M.; Aras, N.; Yalın, S.; Çömelekoğlu, Ü.
Radio-frequency electromagnetic radiation (RF-EMR) represents one of the environmental factor that influence animal organism to stress. In this study we determined the oxidative stress parameters from rat liver, kidney and brain tissues that were exposed to chronic 1800 MHz RF-EMR. Our study was designed in 3 groups as 9 animals in each group. These are; control, sham and RF-EMR exposed group. The control group was not exposed to any procedure; sham group was housed in the same room under the same conditions with equal time period, except that the generator was turned off. RF-EMR exposed group was subjected to 1800 MHz RF-EMR emitted from the signal generator for 2 h per day for eight weeks. All animals that completed the experimental period were sacrificed and liver, kidney and brain tissues of all rats were isolated for analyzing malondialdehyde (MDA), nitric oxide (NO) and reduced glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activities. Liver, kidney and brain MDA and NO levels were higher and GSH level and SOD and catalase activities were significantly lower in RF-exposed group than control and sham groups (p<0.001). No significant difference was observed in terms of tissue MDA, GSH and NO levels and SOD and catalase activities between control and sham groups in each tissue. The results of our study shows that RF-EMR may act as an environmental stressor and cause oxidative and nitrosative damage in liver, kidney and brain tissues. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
4d Oranı ve Parmak Boyları Açısından Obsesif Kompulsif Bozukluk, Yaygın Gelişimsel Bozukluk Tanısı Konulan Çocuklar ve Sağlıklı Kontrollerin Karşılaştırılması
(2016) Bahcelıoglu, Meltem; Buru, Ece; Taner, Hande Ayraler; Gözil, Rabet; İşeri, Elvan
Amaç: Obsesif kompulsif bozukluk ( OKB) ve otizm, tekrarlayıcı davranışlar gibi bazı ortak özelliklere sahiptirler. Prenatal androjenlere maruziyet ile ilişkili olduğu düşünülen, cinsiyetler arasında faklılık gösteren; 2. Parmağın 4. Parmağa oranının (2d:4d) otizmde daha çok \"erkek benzeri\" olduğu bildirilmektedir. Bu çalışmanın amacı ortak özellikleri bulunan OKB ve otizm grubunun 2d:4d oranı ve parmak uzunlukları açısından karşılaştırılmasıdır. Yöntem: Bu çalışmaya 6-18 yaşları arasında olan OKB tanısı konulan 15, Yaygın gelişimsel bozukluk ( YGB ) tanısı konulan 12 ve herhangi bir psikiyatrik bozukluğu olmayan 54 erkek sağlıklı çocuk-ergen dahil edilmiştir. Hasta grubunda OKB ve YGB tanısı ayrıntılı klinik değerlendirme sonucunda DSM IV-TR tanı kriterlerine göre konulmuştur. Değerlendirme sonrasında dijital kompas yardımıyla çocuk ve ergenlerin el uzunluğu, el genişliği, parmak uzunlukları ölçülmüştür. Bulgular : Kontrol, OKB ve YGB grupları arasında sağ ve sol 2d:4d oranı yönünden istatistiksel olarak anlamlı farklılık saptanmamıştır. Buna karşın, YGB grubunda sağ el 2. ve 3.parmaklar ile, sol el 2,3,4. parmakların kontrol grubuna göre daha kısa olduğu saptanmıştır. Sol el uzunluğu YGB grubunda OKB grubuna göre daha kısa olarak saptanırken, sağ 2. ve sol 3. parmak uzunluğu YGB grubunda kontrol ve OKB grubuna göre daha kısa olarak bulunmuştur. Sonuç : Bu çalışmada 2d:4d oranı açısından OKB, YGB ve sağlıklı kontroller arasında herhangi bir farklılık saptanmazken; YGB grubunda bazı parmak boylarının kontrol grubuna göre daha kısa olduğu tespit edilmiştir. Bu bulgu YGB grubunda taranabilecek bir dismorfolojik bir bulgu olabilir ancak daha geniş örneklemlerle yapılacak ileri çalışmalara ihtiyaç duyulmaktadır.
Abc, Ved, and Abc-Ved Matrix Analyses for Inventory Management in Community Pharmacies: a Case Study
(Society of Pharmaceutical Sciences of Ankara (FABAD), 2022) Dursa, E.; Arslan, M.
Inventory control methods should be used effectively in community pharmacies to determine and obtain the needs for pharmaceuticals and non-pharmaceutical products at appropriate times and with proper procedures. An effective stock control provides positive outputs in the community pharmacy’s economy, the quality of the service to be provided, and the pharmacy’s image. In this context, within the scope of this study, it aims to evaluate ABC, VED, and ABC-VED matrix analyses in terms of community pharmacies. In the study, ABC, VED, and ABC-VED matrix analyzes were applied using the inventory data of a community pharmacy serving in the city center of Van for the 2019-2020 financial year. For this purpose, firstly, annual consumption and expenditure data for each pharmacy item specified for the 2019-2020 financial year were collected. The data were then transferred to an MS Excel spreadsheet, and statistical analysis was performed using MS Excel statistical functions. As a result of ABC-VED analysis, it was determined that the drugs in the first category were of great importance for effective stock control, the drugs in the second category were of medium importance, and the drugs in the third category were of low importance. They are because the pharmacy from which the research data is taken is close to the family health center and the socioeconomic structure of the pharmacy’s environment. This categorization is thought to be appropriate. © 2022 Society of Pharmaceutical Sciences of Ankara (FABAD). All rights reserved.
Abo and Rh Blood Groups Frequency in Men and Women Living in Eastern Turkey
(2006) Dilek, I.; Demir, C.; Bay, A.; Akdeniz, H.; Öner, A.F.
Objective: ABO and Rh blood groups which are basic for determination of blood compatibility consist of the most important tests of blood center. In this study, we aimed to find out the rates of ABO and Rh blood groups in male and female donors in our region. Therefore, donors attending to our blood center within the last five years were investigated taken into account their gender. Methods: Blood groups were examined by gel-centrifugation or tube agglutination methods. Results: Out of totally 33.193 individuals, 14.716 were female (44.3%) and 18.477 males (55.7%), and average age was 34 (range 20-60 years old). Taken into account the whole donors, A blood type was found as 43.8%, O blood type 30.8%, B blood type 16.2% and AB blood type 8.6% in rate. With respect to blood type frequency in genders group A was in the rate of 44.1% and 43.6%, group O 31% and 30.5%, group B 16.3% and 16.1% and group AB 8.6% and 9.8% in women and men, respectively. The Rh positivity rate into totally whole donors was 85.5%, being 86.0% in men and 84.8% in women. Conclusion: ABO and Rh blood groups rates were very near to each other in women and men, and also the average rate was very similar to averages in Turkey.
Actions of Resveratrol and Serotonin Added To Stored Bloods on Lipid Peroxidation and Oxidative Dna Damage
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Huyut, Z.; Şekeroğlu, M.R.; Alp, H.H.; Balahoroğlu, R.; Çokluk, E.
Stored blood for use in diseases such as acute blood loss, injury and anemia can be maintained for about a month. It was reported that some negative changes called "storage lesions" occur in stored bloods time dependently. In order to delay these changes, preservatives are added to stored bloods. In this study, we aimed to determine the effects of resveratrol and serotonin on oxidative DNA and mitochondrial damage and lipid peroxidation in stored blood. Blood was taken from 10 volunteers to different blood bags and each blood was separated into 3 groups (control, resveratrol and serotonin groups). Malondialdehyde (MDA), ubiquinone-10 (CoQ10) and 8-hydroxy-2-deoxyguanosine/106deoxyguanosine (8-OHdG/106dG) levels were determined at baseline and on the 7th, 14th, 21st and 28th day after addition of resveratrol and serotonin. MDA, CoQ10 and 8-OHdG/106dG levels increased over time in the control and serotonin groups (p<0.05). However, resveratrol protected against the time-dependent increase in MDA and CoQ10 values (p>0.05). MDA and CoQ10 levels were significantly lower in the resveratrol-treated group on the 21st and 28th days compared with the other groups (p<0.05). These results show that oxidation sensitivity increased time dependently in stored blood. However, the addition of resveratrol allowed the extension of the blood’s shelf life by protecting against increased lipid peroxidation and oxidized CoQ10. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Active Tectonic Setting and Paleoseismicity of the Sancak-Uzunpazar Fault Zone
(Afet ve Acil Durum Yonetimi Baskanligi (AFAD), 2021) Selcuk, A.S.; Erturac, M.K.; Karabacak, V.; Sancar, T.; Kul, A.O.; Yavuz, M.A.
Sancak-Uzunpazar Fault Zone is N40E-trending sinistral shear zone that has a 50 km length and 5 km width between Karakocan (Elazığ) in southwest and Kaynarpınar (Bingöl) in northeast. The fault extends parallelly to East Anatolian Fault is bounded by the North Anatolian Fault to the northeast and Karakoçan Fault to the southeast. Herein, morphological features, the tectonic setting of the Sancak-Uzunpazar Fault Zone and the first paleoseismological studies on it is represented. The Sancak-Uzunpazar Fault Zone is consist of two parallel segments (called East and West) with a 1.5 km distance. Conducted field studies and aerial photogrometry show that the segments exhibit morphological features like faceted surfaces, faulted scarps, shutter ridges, and offset streams. Especially, average offsets are about 7-12 m along the eastern segment while the cumulative maximum offset reaches 1.1 km. Moreover, revealed paleoseismological data show evidence of at least two surface ruptures during Holocene. Obtained morphological data reveal that the Sancak-Uzunpazar Fault Zone may have a relatively lower slip rate when compared to other active faults in the region and the reflection of the slip rate to the morphology is more evident in the eastern segment. © 2022 Turk Deprem Arastirma Dergisi. All rights reserved.
The Activities of Gst Isozymes in Stomach Tissues of Female Obese Patients
(Walter de Gruyter Gmbh, 2020) Yilmaz, Can; Bulus, Hakan; Oguztuzun, Serpil; Cihan, Mehmethan; Fidan, Ceylan
Objectives: Obesity has become an important public health problem because of its increasing prevalence and relation with many diseases and mortality. Studies have shown its association with oxidative stress. In this study, the effect of obesity on total amount of thiol and some glutathione S-transferase (GST) isozymes were investigated which could serve as an important criteria in dose adjustment of some certain drugs in obese. Methods: The gastric tissues removed by gastrectomy operation from 29 morbid obese female patients were analysed for thiol levels and activities of total GST, GSTT1-1 and GSTM1-1. Patients were grouped according to age, presence of hypertension and/or diabetes, and family history. Results: The average total thiol was 131.22 (+/- 7.74) nmol/mg protein with no significant differences in between the groups. GSTT1 specific activities were about 20% higher in four groups: with ages over 35 years old, with hypertension, without diabetes and finally without family history, with respect to other groups. The differences between total GST and GSTM1 activity levels of experimental groups were not significant. Conclusions: This is the first study to compare activities of GST isozymes and total thiol content in the stomach tissues of obese female patients accompanying some common metabolic disorders, age and family history.
Acute Stroke Management in Türkiye: Intravenous Tissue Plasminogen Activator and Thrombectomy Nörotek: Türkiye Neurology Single Day Study
(Galenos Publ House, 2023) Topcuoglu, Mehmet Akif; Ozdemir, Atilla Ozcan; Arsava, Ethem Murat; Gunes, Aygul; Aykac, Özlem; Gencer, Elif Sarionder; Ozturk, Serefnur
Objective: To reveal the profile and practice in patients with acute stroke who received intravenous tissue plasminogen activator (IV tPA) and/or neurointerventional therapy in Turkiye. Materials and Methods: On World Stroke Awareness Day, May 10, 2018, 1,790 patients hospitalized in 87 neurology units spread over 30 health regions were evaluated retrospectively and prospectively. Results: Intravenous tPA was administered to 12% of 859 cases of acute ischemic stroke in 45 units participating in the study. In the same period, 8.3% of the cases received neurointerventional treatment. The rate of good prognosis [modified Rankin score (mRS) 0-2] at discharge was 46% in 83 patients who received only IV tPA [age: 67 +/- 12 years; National Institutes of Health Stroke Scale (NIHSS): 12 +/- 6; hospital stay, 24 +/- 29 days]; 35% in 51 patients who underwent thrombectomy (MT) alone (age: 64 +/- 13 years; NIHSS: 14.1 +/- 6.5; length of hospital stay, 33 +/- 31 days), 19% in those who received combined treatment (age: 66 +/- 14 years; NIHSS: 15.6 +/- 5.4; length of hospital stay, 26 +/- 35 days), and 56% of 695 patients who did not receive treatment for revascularization (age: 70 +/- 13 years; NIHSS: 7.6 +/- 7.2; length of hospital stay, 21 +/- 28 days). The symptom-to-door time was 87 +/- 53 minutes in the IV treatment group and 200 +/- 26 minutes in the neurointerventional group. The average door-to-needle time was 66 +/- 49 minutes in the IV tPA group. In the neurothrombectomy group, the door-to-groin time was 103 +/- 90 minutes, and the TICI 2b-3 rate was 70.3%. In 103 patients who received IV tPA, the discharge mRS 0-2 was 41%, while the rate of mRS 0-1 was 28%. In 71 patients who underwent neurothrombectomy, the mRS 0-2 was 31% and mRS 0-1 was 18%. The door-to-groin time was approximately 30 minutes longer if IV tPA was received (125 +/- 107 and 95 +/- 83 minutes, respectively). Symptomatic bleeding rates were 4.8% in IV recipients, 17.6% among those who received only MT, and 15% in combined therapy. Globally, the hemorrhage rate was 6.8% in patients receiving IV tPA and 16.9% in MT. Conclusion: IV thrombolytic and neurointerventional treatment applications in acute ischemic stroke in Turkiye can provide the anticipated results. Heterogeneity has begun to be reduced in our country with the dissemination of the system indicated by the "Directive on Health Services to be Provided to Patients with Acute Stroke."
Adsorption of Acid Blue 25 on Peach Seed Powder: Isotherm, Kinetic and Thermodynamic Studies
(Yildiz Technical University, 2019) Kul, A.R.; Aldemir, A.; Elik, H.
In the present study peach seed powder (PSP) was used as an adsorbent to remove Acid Blue 25 (AB25) a common basic dye, from aqueous solution. The adsorption experiments were carried out in a batch system and the effects of initial concentration, interaction time and temperature were investigated. The Langmuir, Freundlich and Temkin adsorption isotherms were used to model the equilibrium data. The kinetic parameters were determined by the pseudo first order (PFO), pseudo second order (PSO) and intra-particle diffusion (IPD) models. According to the results, the Freundlich isotherm model is a more convenient option compared with the Langmuir and Temkin models. The Freundlich model coefficients increased as the temperature increased, which shows that the adsorption process becomes more favorable with higher temperature. The experimental and calculated qe values close to one another indicated that this process fits the PSO kinetic model with higher R2 values than the other two models. Kinetic constants become closer to both the temperatures and initial concentrations and qe values increases with the increasing concentration of AB25. The initial dye concentration increased from 25 to 150 mg L-1, while the dye adsorption capacity onto PSP increased from 4.80 to 39.01 mg g-1, from 5.57 to 44.27 mg g-1 and from 6.80 to 49.22 mg g-1 for 298, 308 and 323 K, respectively. The monolayer adsorption capacity (qm) of PSP was determined to be 56.18, 64.94, 95.24 mg g-1 for 298, 308 and 323 K, respectively. Thermodynamic parameters for free energy (ΔG), enthalpy (ΔH) and entropy (ΔS) of the separation process were determined as -1737,1 J mol-1, 14.776 kJ mol-1 and 55,413 J mol-1, respectively. The negative values of ΔGo showed that this separation process was endothermic and natural. The results of the present study demonstrated that PSP can be used as an alternative material in dye removal. © 2023 Bulletin of Monetary Economics and Banking.
Adsorption of Basic Blue 41 Using Juniperus Excelsa: Isotherm, Kinetics and Thermodynamics Studies
(Yildiz Technical University, 2019) Kul, A.R.; Aldemir, A.; Alkan, S.; Elik, H.; Caliskan, M.
In this study Juniperus excelsa shavings powder (JESP) was utilized as an adsorbent for the removal of Basic Blue 41 (BB 41) which is one of the common basic dyes, from aqueous solution. The adsorption experiments were carried out in a batch system and effects of initial concentration of dye, interaction time and temperature were investigated. Langmuir, Freundlich and Temkin adsorption isotherms were used to model equilibrium data. According to the results, Freundlich isotherm model becomes more convenient option compared with Langmuir and Temkin models. Freundlich model coefficients are raise as the temperature rises, showing that the adsorption process becomes favorable higher temperature. The kinetic parameters were determined by pseudo first order (PFO), pseudo second order (PSO) and intra-particle diffusion (IPD) models. Results indicated that experimental and calculated qe values are matched to each other. Thus the process fits PSO kinetic model with higher R2 values than other two models. Kinetic constants become closer to both temperatures and initial concentrations and qe values are increases with increasing concentration of BB 41. Initial dye concentration elevates from 25 to 100 mg L-1, dye adsorption capacity onto JESP from 3.06 to 16.53 mg g-1, respectively. Thermodynamic parameters for instance free energy (ΔG), enthalpy (ΔH) and entropy (ΔS) were assessed. Enthalpy and entropy of this separation process are determined from 3081.91 J mol-1 and 12.33 kJ mol-1, respectively. The negative values of ΔG° showed that this separation process was endothermic and natural. The research results demonstrate that JESP may be a substitute than pricey adsorbents for dye removal. © 2019 Yildiz Technical University. All rights reserved.
Adult Patient Cancer Statistics of Mardin Province
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Aytekin, A.
Some types of cancer are more common in some regions. The data in Turkey are recorded with the cancer registry system but this data does not cover all cities. This study aimed to investigate the clinical and demographic characteristics of oncology patients admitted to Mardin State Hospital. The records of patients, who admitted to Mardin State Hospital Medical Oncology Clinic between 2014-2018, were retrospectively reviewed. Patients over 18 years of age were included in the study. Gender, diagnosis and disease stages of the patients were recorded. The median age of the 1208 patients (654 female and 554 male) was 57 (18-94) years. The median age was 52.25 in women and 60.92 in men. The 5 most common cancers in the whole group were; breast cancer, colorectal cancer, lung cancer, prostate cancer and gastric cancer, respectively. In men; the most common types of cancer were; lung, colorectal, prostate, head-neck and gastric cancer. On the other hand in women, the most common types of cancer were breast, colorectal, ovarian, gastric and uterus corpus cancer. The most common presentation stage was stage 4 (n = 416, 34.4%) in the whole group, stage 2 (n = 204, 31.2%) in women and stage 4 (n = 253, 45.7%) in men. Adenocarcinoma was the most common histologic type in both the male and the whole group (female and male) of patients. The most common histological types in women was breast carcinomas (invasive lobular and ductal carcinomas). In this study, the incidence of colorectal cancer in all groups (men, women and total) was higher in Mardin province when compared with Turkey data. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Advances in Current Medication and New Therapeutic Approaches in Epilepsy
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Allahverdiyev, O.; Dzhafar, S.; Berköz, M.; Yıldırım, M.
Epilepsy is one of the most complicated neurological disorders associated with a brain disorder in which, after an in itial physiological insult, the networks of neurons regroup and communicate abnormally that can be defined as the neuronal hyper -synchronizayion. The affected part of brain defines the patient’s abnormality behavior. Unlike the younger patients, who can become seizure free after the age of 16-18, older patients are hardly able to overcome the seizures, especially once the type of seizure developed to generalize tonic-clonic phase. Globally, epilepsy is considered as a disease which is originated from the disorder of electrical function of the brain and estimated to effect approximately 50 million people worldwide. Pharmacoresistance, drug interactions, drug tolerability and various adverse effects are among the common problems associated with the treatments of epilepsy with antiepileptic drugs (AEDs). Although, approximately 70% of the patients exhibit seizures that can be controlled with most AEDs, the remaining 30% of the patients fail to respond to treatment with AEDs. Thus, looking for alternatives such as traditional treatment methods like utilizing medicinal plants, ketogenic diet, and the Atkins diet as well as self-physical therapy like relaxation and yoga, are all positive options that can be considered as replacement and supportive therapy methods for the medications which are used in seizure control of epilepsy. Medicinal plants are more commonly used by folk for making infusions administered as herbal teas for the pain relief and maintaining good health. Investigating the active components of a plant extract, isolating and identifying their structure and pharmacological effects, and finally utilizing them as a new agent from nature with fewer side effects and high economic valu e is a widely interested topic in the field of ethnoparmacology. In addition to AEDs, which are currently used, the suggested alternative therapies are also able minimize the seizures of epilepsy but the surgical intervention still remains as the last option in the treatment of epilepsy. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Akciğer Hastalarında Sigara İçme Sıklığı
(2000) Özbay, Bülent; Uzun, Kürşat; Ceylan, Erkan
Bu çalışmanın amacı akciğer hastalığı olan olgular arasında sigara içme sıklığını araştırmaktır. Bu çalışmada 431 olgunun dosyası sigara anamnezine göre retrospektif olarak incelendi. Olguların yaş ortalaması 48.2 ± 17.4 olup 306'sı erkek, 124'ü kadın idi. İncelenen tüm olguların %58'inde sigara içme alışkanlığı olup ortalama 21.9 ± 28.9 paket yıl sigara içmekteydi. Tüm olguların ortalama sigaraya başlama yaşı 21.7 ± 10.3 idi. Olgular etyolojik tanılarına göre 6 gruba ayrıldı (KOAH, malignite, Tb, bronş astımı, pnömoni ve diğerleri grubu). Sigara kullanan 251 olgunun %74.1'i aktif içici, %25.9'u sonradan sigarayı bırakanlardan oluşuyordu. Aktif sigara içenlerin %32.3'ünü maligniteli grup oluşturmaktaydı. Sonradan sigarayı bırakanlar arasında birinci sırayı KOAH'lılar alıyordu. Ortalama sigara içme süresi paket-yıl olarak KOAH'lılarda 34.1 ± 31.07, akciğer kanserinde 44.1 ± 31.9 idi. Sigara içme süresi malign akciğer hastalıklarında en fazla olup, diğer gruplar ile arasında istatiksel olarak anlamlı farklılık mevcut idi. Sigara kullanan olguların %49'unun sigaraya başlama yaşı 10-20 yaş arasında idi. Maligniteli olguların sigaraya başlama yaşı ortalama 24.3 ± 15.6 yaş, KOAH'lıların 30.9 ± 18.4 yaş idi. Günlük içilen sigara miktarı olarak malignitelilerde 1.5 ± 0.6 paket/gün, KOAH'lılarda 1.4 ± 0.6 paket/gün, pnömonilerde 1.4 ± 0.6 paket/gün, bronş astımlılarda 1.4 ± 0.5 paket/gün, tüberkülozlularda 1.1 ± 1.4 paket/gün ve diğerleri grubunda 1.1 ± 0.3 paket/gün idi. Bu bulgular bize aktif içicilerin çoğunluğunu malignite ve KOAH'lıların oluşturduğunu ve içme süresinin-içilen miktarın en fazla bu gruplarda olduğu gözlendi.
Akkaraman Irkı Koyunlarda Holotrich ve Entodiniomorphid Siliyatların (Protozoa: Ciliophora) Günlük Değişimi
(2001) Şenler, Naciye Gülkız; Yıldız, Ismaıl
Bu çalışmada, Yüzüncü Yıl Üniversitesi Ziraat Fakültesi'nde günde iki kez yemlenen ve işkembesinde fistül açılmış iki Akkaraman ırkı koyundaki işkembe siliyat sayısının günlük değişimleri incelenmiştir. Siliyat sayısı ile işkembe içeriği pH değerleri arasındaki ilişki önemsiz bulunmuştur. Değişime etken faktörler literatür bilgisi ile karşılaştırılarak tartışılmıştır
Aktif Dinleme
(2007) Çiftçi, Ömer
Öğrenmenin ve bilgi sahibi olmanın en önemli vasıtalarından biri dinlemedir. Dinleme, konuşanın vermek istediği mesajı tam ve doğru olarak almaktır. Buna rağmen bütün dinlemeler anlamayla sonuçlanamayabilir. Dinleyicinin dikkati ve psikolojik durumu mesajı almasında önemli rol oynar. Konuşan kimse, dinlendiğini ve konuşmalarına ilgi gösterildiğini bilmek; dinleyen ise konuşmacıyı rahatlatmak ve dinlendiğine inandırmak ister. Bu aşamadan sonra aktif dinleme dediğimiz dinleme türü devreye girer. Aktif dinleme, dinleyen kimsenin söylenenleri anladığını söz ya da imalarla konuşmacıya hissettirmesi veya bir şeklide konuşmaya müdahil olmasıdır. Aktif dinleme sonucunda konuşmacı rahatlamaya kavuşurken dinleyici de anlamanın hazzma varır. Aktif dinleme, bütün kaynaklarda en etkili dinleme türü olarak tarif edilmiştir. Bu tür dinlemenin neticesinde mutlaka anlama gerçekleşir. Özellikle ailede ve okulda ebeveynlerin ve öğretmenlerin hatta öğrencilerin aktif dinleme yapmaları iletişimi ve anlaşılmayı kolaylaştıracaktır. Bu çalışmada dinleme, aktif dinlemenin bir süreci olan iletişimin unsurları, aktif dinleme, aktif dinlemede uygulanacak teknikler ve aktif dinlemenin aile ve eğitim-öğretim ortamındaki faydaları üzerinde durulmuştur.
Albendazol Kullanımı Sonrası, Nadir Bir Komplikasyon: Kronik Granulamatöz İnflamasyon (Olgu Sunumu)
(2004) Işık, Ahmet Feridun; Bayram, İrfan; Er, Metin
Akciğer hidatik kistleri halen ülkemiz için önemli bir sorun olarak durmaktadır. Tedavisinde öncelik cerrahi yöntemler kullanılırken, son 15 yılda benzimadazol karbamat grubu ilaçlar denenmektedir. Ancak bu tedavi, akciğerlerin dışarıya açık organlar olması nedeniyle tam kür sağlamayabilmektedir. Canlılığını yitiren kistler komplikasyonlara açık hale gelmektedir. Bunlar tekrarlayan enfeksiyon, apse, bronşektazi, hemoptizi ve ağır pnömoni olarak sayılabilir. Patoloji raporunda eşlik eden kronik kazeifiye granulamatöz iltihap bildirilmesi üzerine, akciğer hidatik kistlerinin ilaçla tedavisinin yol açabileceği komplikasyonlan vurgulamak amacıyla olgumuzu paylaşmak istedik.
Amniocentesis Results of Van and Surrounding Provinces Between 2018 and 2020: a Tertiary Center Experience
(Yuzuncu Yil Universitesi Tip Fakultesi, 2021) Küçükbaş, G.N.; Dirik, D.; Karaaslan, O.; Karaman, E.; Kolusari, A.; Aymelek, H.S.; Şahin, H.G.
Amniocentesis is one of the safest procedures of prenatal diagnosis. This study aimed to show amniocentesis indications, rate of successful amniocyte culture, complications and outcomes of these pregnancies undergoing prenatal diagnosis in eastern part of Turkey, especially Van province and its nearby. Between 2018 and 2020, 253 patients were referred to our center for amniocentesis and 120 patients giving consent were enrolled from Van and its surrounding provinces. The most frequent indication was high risk in prenatal screening tests whereas the highest chromosomal abnormality was found in fetuses with abnormal ultrasonographic findings. Overall, 11.6% of fetuses had chromosomal anomaly. The most abundant chromosomal abnormality was Trisomy 21, followed by trisomy 18 and 13. Except one case with amniotic leakage no complications were found. Eleven pregnancies were terminated whereas one fetus was born with Turner syndrome and two pregnancies resulted with stillbirth. In conclusion, fetuses with abnormal ultrasound screening had higher chromosome anomaly diagnosed by amniocentesis and compatible with the literature, amniocentesis is a safe and successful method of prenatal diagnosis of chromosomal abnormalities. Van and its surrounding provinces showed a high rate of chromosomal anomaly when prenatal diagnosis was done. © 2021, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Anadili Dersinin Etkinlik Alanları ve Dilbilgisi
(2009) Aydın, İlker
Kişinin annesinden ve yakın çevresinden edindiği dildir anadili. Bazı olağanüstü durumlar dışında, genellikle çocukların annelerinin dilini edindiği gözlemlenmektedir. Çocuk, okula başlayana kadar, ailesi ve yakın çevresinden doğal yollarla, düzensiz olarak öğrendiği anadilini, okulla birlikte, düzenli bir biçimde edinmeye başlar. Anadili öğretiminin temel amacı, okuduğunu, dinlediğini anlayan düşündüklerini yazılı ve sözlü anlatabilen bireyler yetiştirmektir. Anadili öğretimi tek boyutlu bir bilgi ve beceri alanı olmayıp çok yönlü ve girişik etkinlikleri içeren bir özelliğe sahiptir. Dil öğretiminin temelinde dört temel dil becerisi olarak kabul edilen dinleme, konuşma, okuma ve yazmanın geliştirilmesi görüşü vardır ve dilsel becerilerin bir bütünlük içinde, dengeli bir biçimde geliştirilmesi amaçlanır. Bu çalışma temelde iki bölümden oluşmaktadır. Birinci bölümde anlama, anlatma ve dilbilgisi çalışmalarından oluşan Türkçe öğretiminin etkinlik alanları tanıtılmıştır. Çalışmanın ikinci bölümünde ise, anadili öğretiminde konu alanı olarak değerlendirilen dilbilgisi üzerine örnek bir çalışma yapılmış; böylece bir dil incelemesi modeli oluşturmaya çalışılmıştır.
Anadolu Kültüründe Kilit ( Doğu ve Güneydoğu Anadolu Örnekleri )
(2008) Karakas, Bulent; Saraçoğlu, Semra
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