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Hepatorprotective Effect of Foeniculum Vulgare Essential Oil

dc.authorid Erdogan, Ender/0000-0002-6220-9243
dc.authorid Ugras, Serdar/0000-0003-0108-697X
dc.authorwosid Erdogan, Ender/Abc-7081-2020
dc.authorwosid Ugras, Serdar/R-7235-2019
dc.authorwosid Ozbek, Hanefi/O-3472-2019
dc.contributor.author Özbek, H
dc.contributor.author Ugras, S
dc.contributor.author Bayram, I
dc.contributor.author Uygan, I
dc.contributor.author Edrogan, E
dc.contributor.author Öztürk, A
dc.contributor.author Huyut, Z
dc.date.accessioned 2025-05-10T16:59:28Z
dc.date.available 2025-05-10T16:59:28Z
dc.date.issued 2004
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Yuzuncu Yil Univ, Fac Med, Dept Histol, Van, Turkey; Yuzuncu Yil Univ, Fac Med, Dept Gastroenterol, Van, Turkey; Yuzuncu Yil Univ, Fac Med, Dept Pathol, Van, Turkey; Yuzuncu Yil Univ, Fac Med, Dept Pharmacol, Van, Turkey en_US
dc.description Erdogan, Ender/0000-0002-6220-9243; Ugras, Serdar/0000-0003-0108-697X en_US
dc.description.abstract Hepatoprotective activity of Foeniculum vulgare (fennel) essential oil was studied using a carbon tetrachloride-induced liver fibrosis model in rats. The hepatotoxicity produced by chronic carbon tetrachloride administration was found to be inhibited by Foeniculum vulgare essential oil with evidence of decreased levels of serum aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and bilirubin. Histopathological findings also suggest that Foeniculum vulgare essential oil prevents the development of chronic liver damage. The changes in body weights in the rats assigned to the study groups supported these biochemical and histopathological findings. The results of this study clearly indicate that Foeniculum vulgare essential oil has a potent hepatoprotective action against carbon tetrachloride-induced liver fibrosis in rats. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.endpage 17 en_US
dc.identifier.issn 0901-3393
dc.identifier.issue 1 en_US
dc.identifier.scopusquality Q4
dc.identifier.startpage 9 en_US
dc.identifier.uri https://hdl.handle.net/20.500.14720/4640
dc.identifier.volume 31 en_US
dc.identifier.wos WOS:000220785300003
dc.identifier.wosquality Q3
dc.language.iso en en_US
dc.publisher Scandinavian Federation Laboratory Animal Science en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Foeniculum Vulgare Miller en_US
dc.subject Fennel Essential Oil en_US
dc.subject Feo en_US
dc.subject Carbon Tetrachloride en_US
dc.subject Liver Fibrosis en_US
dc.subject Hepatoprotective Effect en_US
dc.title Hepatorprotective Effect of Foeniculum Vulgare Essential Oil en_US
dc.type Article en_US

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