Nephrological Problems in Covid-19 Patients
No Thumbnail Available
Date
2022
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Amaç: 2019 yılında ortaya çıkan SARS CoV-2 virüsü ve meydana getirdiği pandemi tüm dünyayı etkisi altına almıştır. Pandeminin nefrolojik etileri merak konusu olmuştur. Bu çalışmada klinik ve yoğun bakımda yatan COVID-19 pozitif hastalarda nefrolojik problemler araştırıldı. Gereç ve Yöntem: Araştırma gözlemsel kesitsel retrospektif bir çalışmadır. Kasım 2020 –Kasım 2021 tarihleri arasında COVID-19 Yoğun Bakım Ünitesi ve COVİD-19 kliniklerinde takip edilen 18-90 yaş arası hastalardan gönderilen kan ve idrar tahlilleri incelendi. Çalışmaya 79 hasta dahil edildi. COVID-19 tanısı, RT-PCR, toraks BT ve klinik durum gözetilerek konuldu. Bu 79 hastanın akut böbrek hasarı(ABH), elektrolit imbalansı ve tam idrar tetkiki bozuklukları açısından karşılaştırılması yapıldı. Ayrıca COVİD-19 tanılı grupta hastaların yaş, cinsiyet bilgileri ve yattığı klinik açısından da karşılaştırması yapıldı. Bulgular: Retrospektif olarak yaptığımız çalışmamızda 79 hastanın %32,9 unda ABH tespit edildi. ABH'ı olan hastaların %42,3'ü kadın, %57,7'si erkek idi. ABH'ı olan hastaların %73,1'i yoğun bakımda yatan hastalar idi. Tam idrar tekiki çalışılan hastaların %65'inde hematüri tespit edildi. Tam idrar tetkiki çalışılan hastaların %27'sinde proteinüri tespit edildi. Ayrıca elektrolit imbalansı açısından da karşılaştırma yapıldığında sodyum çalışılan hastaların %44'ünde hiponatremi, %4'ünde hipernatremi, potasyum çalışılan hastaların %13'ünde hipokalemi, %11'inde hiperkalemi, fosfor çalışılan hastaların %11'inde hipofosfatemi, %6'sında hiperfosfatemi, magnezyum çalışılan hastaların %9 unda hipomagnezemi, %3 ünde hipermagnezemi tespit edildi. Kalsiyum çalışılıp hipokalsemisi olan hastaların sayısı 19 (%24) olarak tespit edildi. Albümin çalışılan hastaların %65'inde de hipoalbuminemi tespit edildi. Sonuç: COVID-19 tanısı alan ve yatırılıp takip ve tedavisi yapılan hastalarda ABH, hematüri ve proteinüri istatistiksel olarak anlamlı sonuç verdi. Ayrıca hastalarda elektrolit imbalansı ve hipoalbuminemi de mevcuttur. C0VİD-19 hastalarının takipleri nefrolojik açıdan dikkatle izlenmelidir
Aim: The SARS CoV-2 virus that emerged in 2019 and the emerging pandemic are full of journeys. The nephrological effects of the pandemic have been a matter of curiosity. In this study, nephrological problems were investigated in COVID-19 positive patients hospitalized in clinical and intensive care units. Materials and Methods: The research is an observational cross-sectional retrospective study. Between November 2020 and November 2021, blood and urine analyzes sent from patients aged 18-90 who were followed up in the COVID-19 Intensive Care Unit and COVID-19 clinics were examined. 79 patients were included in the study. The diagnosis of COVID-19 was made by considering RT-PCR, thorax CT and clinical situation. These 79 patients were compared in terms of acute kidney injury (AKI), electrolyte imbalance and complete urinalysis disorders. Results: In our retrospective study, AKI was detected in 32.9% of 79 patients. 42.3% of patients with AKI were female, 57.7% were male. 73.1% of the patients with AKI were hospitalized in the intensive care unit. Hematuria was detected in 65% of the patients studied in complete urine analysis. Proteinuria was detected in 27% of the patients whose complete urinalysis was studied. In addition, the patients in the group diagnosed with COVID-19 were compared in terms of age, gender information and the clinic they were hospitalized. In addition, when compared in terms of electrolyte imbalance, hyponatremia in 44%, hypernatremia in 4%, hypokalemia in 13%, hyperkalemia in 11%, hypophosphatemia in 11% of patients studied for phosphorus, and hypophosphatemia in 6% of patients studied for sodium. Hyperphosphatemia, hypomagnesemia was found in 9% of the patients in whom magnesium was studied, and hypermagnesemia was found in 3% of them. The number of patients with hypocalcemia after calcium studies was found to be 19 (24%). Hypoalbuminemia was also detected in 65% of the patients in whom albumin was studied. Conclusion: Acute kidney injury, hematuria and proteinuria were statistically significant in patients diagnosed with COVID-19 and hospitalized and followed up. There are also electrolyte imbalances and hypoalbuminemia in patients. Follow-up of patients with COVID-19 should be carefully monitored in terms of nephrology.
Aim: The SARS CoV-2 virus that emerged in 2019 and the emerging pandemic are full of journeys. The nephrological effects of the pandemic have been a matter of curiosity. In this study, nephrological problems were investigated in COVID-19 positive patients hospitalized in clinical and intensive care units. Materials and Methods: The research is an observational cross-sectional retrospective study. Between November 2020 and November 2021, blood and urine analyzes sent from patients aged 18-90 who were followed up in the COVID-19 Intensive Care Unit and COVID-19 clinics were examined. 79 patients were included in the study. The diagnosis of COVID-19 was made by considering RT-PCR, thorax CT and clinical situation. These 79 patients were compared in terms of acute kidney injury (AKI), electrolyte imbalance and complete urinalysis disorders. Results: In our retrospective study, AKI was detected in 32.9% of 79 patients. 42.3% of patients with AKI were female, 57.7% were male. 73.1% of the patients with AKI were hospitalized in the intensive care unit. Hematuria was detected in 65% of the patients studied in complete urine analysis. Proteinuria was detected in 27% of the patients whose complete urinalysis was studied. In addition, the patients in the group diagnosed with COVID-19 were compared in terms of age, gender information and the clinic they were hospitalized. In addition, when compared in terms of electrolyte imbalance, hyponatremia in 44%, hypernatremia in 4%, hypokalemia in 13%, hyperkalemia in 11%, hypophosphatemia in 11% of patients studied for phosphorus, and hypophosphatemia in 6% of patients studied for sodium. Hyperphosphatemia, hypomagnesemia was found in 9% of the patients in whom magnesium was studied, and hypermagnesemia was found in 3% of them. The number of patients with hypocalcemia after calcium studies was found to be 19 (24%). Hypoalbuminemia was also detected in 65% of the patients in whom albumin was studied. Conclusion: Acute kidney injury, hematuria and proteinuria were statistically significant in patients diagnosed with COVID-19 and hospitalized and followed up. There are also electrolyte imbalances and hypoalbuminemia in patients. Follow-up of patients with COVID-19 should be carefully monitored in terms of nephrology.
Description
Keywords
İç Hastalıkları, Akut böbrek hasarı, Böbrek hastalıkları, COVID 19, Elektrolitler, Hematüri, Korona virüs enfeksiyonları, Korona virüsler, Nefroloji, Proteinüri, Retrospektif çalışmalar, Internal diseases, Acute kidney injury, Kidney diseases, COVID 19, Electrolytes, Hematuria, Coronavirus enfections, Coronaviridae, Nephrology, Proteinuria, Retrospective studies
Turkish CoHE Thesis Center URL
WoS Q
Scopus Q
Source
Volume
Issue
Start Page
End Page
123