Determination of Lethal Doses of Volatile and Fixed Oils of Several Plants
No Thumbnail Available
Date
2004
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Objective: To determine lethal doses of fixed and/or volatile oils extracted from leafs or fruits of Pimpinella anisum, Foeniculum vulgare, Sesamum indicum, Eugenia caryophyllata, Nigella sativa, Urtica pilulifera, Apium graveolens, Cuminum cyminum, Coriandrum sativum and Thymus fallax, Method: Swiss albino mice were injected intraperitoneally with different concentrations of the extract and results were evaluated with the method of probit analysis. Results: Maximum volume of oil administered to mice was kept below 0.5 ml. The oils of Sesamum indicum and Urticapilulifera was completely non-lethal even at doses reaching 12.8 ml/kg and considered non-toxic. Conclusion: Lethal doses were determined for all other plants and LD1, LD10, LD50, LD90 and LD99 values were given.
Description
Keywords
Fixed Oil, Lethal Doses, Plants, Volatile Oil
Turkish CoHE Thesis Center URL
WoS Q
N/A
Scopus Q
Q4
Source
Eastern Journal of Medicine
Volume
9
Issue
1
Start Page
4
End Page
6