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Morphological and Functional Changes in Rat Brain Under Total Sleep Deprivation

dc.authorscopusid 6602244566
dc.authorscopusid 56000011200
dc.authorscopusid 57986528400
dc.contributor.author Abushov, B.
dc.contributor.author Temur, A.
dc.contributor.author Temiz, M.A.
dc.date.accessioned 2025-05-10T17:00:44Z
dc.date.available 2025-05-10T17:00:44Z
dc.date.issued 2015
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Abushov B., Institute of Physiology N.a. A.I. Karayev, Azerbaijan National Academy of Sciences, Azerbaijan; Temur A., Yüzüncü Yil University, Faculty of Education, Van, 65080, Turkey; Temiz M.A., Yüzüncü Yil University, Faculty of Education, Van, 65080, Turkey en_US
dc.description.abstract In this article the effect of 36 h total sleep deprivation (TSD) on behavioural reactions of rats (rearing, grooming and sexual activity) and on ultrastructure of brain neurons have been studied. A group of somnogenic structures (III-V layers of the frontal limbic cortex, CA1 area of the dorsal hippocampus, reticular formation of pons varolli, nucleus raphe dorsalis and locus coeruleus) of the brain of 6 month-old Wistar rats has been analized in this study. It has been revealed that dystrophic changes (chromatolysis of cytoplasm and vacuolization) enveloping a group of medium-sized neurons (20-30 (μ) micron in diameter) are accompanied by decrease of numbers of rearing, grooming and sexual activity. It is supposed that dystrophic changes revealed in medium-sized neurons result in partial disturbances of integrative and behavioral reactions of animals. en_US
dc.identifier.doi 10.16988/iuvfd.2015.45988
dc.identifier.endpage 142 en_US
dc.identifier.issn 0250-2836
dc.identifier.issue 2 en_US
dc.identifier.scopus 2-s2.0-84939426311
dc.identifier.scopusquality N/A
dc.identifier.startpage 138 en_US
dc.identifier.uri https://doi.org/10.16988/iuvfd.2015.45988
dc.identifier.uri https://hdl.handle.net/20.500.14720/4915
dc.identifier.volume 41 en_US
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Istanbul University en_US
dc.relation.ispartof Istanbul Universitesi Veteriner Fakultesi Dergisi en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Behavioral Reactions en_US
dc.subject Neurons en_US
dc.subject Total Sleep Deprivation en_US
dc.title Morphological and Functional Changes in Rat Brain Under Total Sleep Deprivation en_US
dc.type Article en_US

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