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Evaluation of Effectiveness of Hemogram Parameters in Colorectal Cancer Screening

dc.authorscopusid 56941615100
dc.authorscopusid 59909912200
dc.contributor.author Aras, A.
dc.contributor.author Oğuz, E.
dc.date.accessioned 2025-06-30T15:25:50Z
dc.date.available 2025-06-30T15:25:50Z
dc.date.issued 2025
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Aras A.] Department of General Surgery, Van Yuzuncu Yil University Faculty of Medicine, Van, Turkey; [Oğuz E.] Department of General Surgery, Van Yuzuncu Yil University Faculty of Medicine, Van, Turkey en_US
dc.description.abstract Colorectal cancer (CRC) frequency and cancer-related death rates can be reduced with screening methods. Due to the invasiveness of the colonoscopy procedure and the high rate of false positivity of stool-based tests, it was aimed to investigate whether hemogram parameters could be a potential alternative to assist screening methods. Between January 2023 and December 2024 at Van YYU Faculty of Medicine Hospital, 605 patients who underwent colonoscopy for various indications were divided into groups and the age, gender, hemogram parameters taken before colonoscopy, such as RBC Count, Hb, Hct, WBC Count, Platelet Count, MPV, MC V, RDW, NLR, PLR, MLR, MPV/PLT ratio, Hb/PLT ratio, Lymphocyte/Monocyte ratio and the Hb/RDW ratio were investigated and then the usability of these hemogram parameters in colorectal cancer screening was studied. Statistical differences were observed in WBC, Hemoglobin, hematocrit, MCV, RDW, lymphocyte, MPV/PLT, Hb/PLT, Lymphocyte/monocyte and Hb/RDW ratios with T Test between cancer patients and patients with normal colonoscopy findings. Additionally, in multiple group comparisons, a statistically significant difference was detected in age, WBC, RBC and MCV parameters. This study is the most comprehensive study ever conducted with 18 hemogram parameters. As a result of binary and multivariate analysis, a statistically significant difference was detected in 10 parameters with T Test and in 4 parameters with multivariate analysis. It was concluded that hemogram parameters will be used alone or in addition to existing screening methods in colorectal cancer screening through prospective studies with the appropri ate combination of these parameters. © 2025, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved. en_US
dc.identifier.doi 10.5505/ejm.2025.00946
dc.identifier.endpage 309 en_US
dc.identifier.issn 1301-0883
dc.identifier.issue 2 en_US
dc.identifier.scopus 2-s2.0-105005888308
dc.identifier.scopusquality Q4
dc.identifier.startpage 302 en_US
dc.identifier.uri https://doi.org/10.5505/ejm.2025.00946
dc.identifier.uri https://hdl.handle.net/20.500.14720/25226
dc.identifier.volume 30 en_US
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Yuzuncu Yil Universitesi Tip Fakultesi en_US
dc.relation.ispartof Eastern Journal of Medicine en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Colorectal Cancer en_US
dc.subject Hemogram Parameters en_US
dc.subject Screening en_US
dc.title Evaluation of Effectiveness of Hemogram Parameters in Colorectal Cancer Screening en_US
dc.type Article en_US

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