Investigation of Free Radical Scavenging Enzyme Activities and Lipid Peroxidation in Liver Tissue of Zinc Deficient Rats
| dc.authorscopusid | 57215511033 | |
| dc.authorscopusid | 7004499173 | |
| dc.authorscopusid | 59105702800 | |
| dc.authorscopusid | 6508353252 | |
| dc.authorscopusid | 24466635800 | |
| dc.authorscopusid | 22937533800 | |
| dc.authorscopusid | 25230530900 | |
| dc.contributor.author | Kaya, H. | |
| dc.contributor.author | Taysi, S. | |
| dc.contributor.author | Kaya, A. | |
| dc.contributor.author | Boyuk, A. | |
| dc.contributor.author | Dursun, H. | |
| dc.contributor.author | Islamoglu, Y. | |
| dc.contributor.author | Cikman, O. | |
| dc.date.accessioned | 2025-05-10T17:51:29Z | |
| dc.date.available | 2025-05-10T17:51:29Z | |
| dc.date.issued | 2008 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | Kaya H., Department of Biochemistry, Nenehatun Obstetric and Gynecology Hospital, Erzurum, Turkey, Mustafa Kernal University, Medical School, Department of Internal Medicine, Hatay, Turkey; Taysi S., Department of Biochemistry, Nenehatun Obstetric and Gynecology Hospital, Erzurum, Turkey; Kaya A., Department of Biochemistry, Nenehatun Obstetric and Gynecology Hospital, Erzurum, Turkey, Department of Internal Medicine, 100 Yil University, Veterinary Faculty, Van, Turkey; Boyuk A., Department of Biochemistry, Nenehatun Obstetric and Gynecology Hospital, Erzurum, Turkey, Department of Surgery, Elazig Research and Educational Hospital, Elazig, Turkey; Dursun H., Department of Biochemistry, Nenehatun Obstetric and Gynecology Hospital, Erzurum, Turkey, Department of Internal Medicine, Ataturk University, Medical School, Erzurum, Turkey; Islamoglu Y., Department of Biochemistry, Nenehatun Obstetric and Gynecology Hospital, Erzurum, Turkey, Cardiology, Ataturk University, Medical School, Erzurum, Turkey; Tastekin D., Department of Biochemistry, Nenehatun Obstetric and Gynecology Hospital, Erzurum, Turkey, Department of Internal Medicine, Medical School, Kafkas University, Kars, Turkey; Cikman O., Department of Biochemistry, Nenehatun Obstetric and Gynecology Hospital, Erzurum, Turkey, Department of Surgery, Van State Hospital, Van, Turkey | en_US |
| dc.description.abstract | The aim of this study was to evaluate the lipid peroxidation and free radical scavenging enzyme activities in liver tissue of zinc (Zn)-deficient rats and investigate relationship among these parameters in either group. 16 Male rats with a weight of 35-40 g were used for the experiment. The rats were divided into control (n = 8) and Zn-deficient groups. After 4 weeks of feeding, the rats were killed by cervical dislocation and liver tissues were removed. Biochemical measurements in liver tissue were carried out using a spectrophotometer. Catalase, glutathione peroxidase, glutathione reductase, glutathione S transferase activities, total (enzymatic plus non-enzymatic) superoxide scavenger activity, superoxide dismutase, non-enzymatic superoxide scavenger activity, superoxide dismutase activities and Zn level in the Zn-deficient group were significantly lower than those of the control group, whereas malondialdehyde level was significantly higher than those of the control group. Slightly increased non-enzymatic superoxide scavenger activity was not significantly different from the controls. The results obtained in this study demonstrate that Zn-deficiency causes a decrease in antioxidant defence system and an increase in oxidative stress in liver tissue in rats. | en_US |
| dc.identifier.endpage | 1074 | en_US |
| dc.identifier.issn | 0970-7077 | |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.scopus | 2-s2.0-53949116558 | |
| dc.identifier.scopusquality | Q4 | |
| dc.identifier.startpage | 1068 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/18145 | |
| dc.identifier.volume | 20 | en_US |
| dc.identifier.wosquality | N/A | |
| dc.language.iso | en | en_US |
| dc.publisher | Chemical Publishing Co. | en_US |
| dc.relation.ispartof | Asian Journal of Chemistry | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Antioxidant Enzymes | en_US |
| dc.subject | Free Radicals | en_US |
| dc.subject | Lipid Peroxidation | en_US |
| dc.subject | Malondialdehyde | en_US |
| dc.subject | Trace Element | en_US |
| dc.subject | Zinc | en_US |
| dc.title | Investigation of Free Radical Scavenging Enzyme Activities and Lipid Peroxidation in Liver Tissue of Zinc Deficient Rats | en_US |
| dc.type | Article | en_US |