Accessing of Common Carotid and Vertebral Arteries at Normal Position and Right-Left Rotation in Ankylosan Spondylitis by Doppler Ultrasonography,matching the Results With Normal Population
Abstract
Amaç: Ankilozan Spondilit hastalarında karotis ve vertebral arter kan volumlerinin doppler USG ile normal populasyonla kıyaslanması. Metod: Ateroskleroz veya servikal arteryel fizyoloji değişikliğine yol açabilecek komorbid durumları olan hastalar ekarte edildi. 50 AS(ankilozan spondilit) li hasta ve 50 sağlıklı insan çalışmaya dahil edildi. Tüm hastalar ve kontrol grubunun nötr-sağ rotasyon-sol rotasyon pozisyonlarında 7,5Mhz lineer prob ile karotis-vertebral arter doppler incelemeleri, intimomedial kalınlık ölçümleri yapıldı. Bulgular: Sağ rotasyon pozisyonunda sağ vertebral arter ve total vertebral arter volümü, sol rotasyon pozisyonunda sol vertebral arter ve total vertebral arter volümünün, AS hastalarında, normal populasyona göre istatistiksel olarak anlamlı şekilde azalmış olduğu tesbit edildi Ayrıca karotis intimomedial kalınlığı, AS hastalarında, normal populasyona göre yüksek çıktı. (p<0,01). Sonuç: AS hastalarında kardiovasküler tutulum nadirdir. Biz çalışmamızda AS hastalarında sağ ve sol rotasyon pozisyonlarında vertebral arter akım volümlerinin (posterior dolaşım), rotasyon tarafında, sağlıklı popülasyona göre azalmış olduğunu tesbit ettik. Karotis volümlerinde ise (anterior dolaşım) anlamlı farklılık tesbit etmedik. Posterior dolaşımda volüm azalmasını AS hastalarında yaygın bir şekilde görülen vertebral sindesmofit ve entezopati gibi durumların vertebral artere bası yapmasına bağladık.Anterior dolaşımın etkilenmemesini ise hemodinamik dengeyi sağlayan otoregülasyon mekanizmaların anterior dolaşımı daha fazla koruyarak defisitleri önlemesine yorumladık.Ayrıca AS hastalarında ,sağlıklı bireylere göre karotis intimomedial kalınlıkta anlamlı derecede artış tesbit ettik.
Objective: The aim of this study is to compare the carotid and vertebral artery flow volumes of the patients with ankylosing spondilitis with age and sex matched controls utilizing the doppler ultrasonography. Material and methods: The patients with comorbid conditions causing atherosclerosis and cerebral arterial flow disturbances, excluded from the study. Finally, a total of 50 patients with ankylosing spondilitis and age/sex matched 50 healthy controls were included in the study. Carotid and vertebral artery flow volumes of all patients and controls were measured by doppler ultrasonography using a 7,5Mhz lineer probe at neutral, left rotational and right rotational pozitions Results: Right vertebral artery and total vertebral artery flow volume at right rotational position, and also left vertebral artery and total vertebral artery flow volume at the left rotational position were found to be statistically significantly lower in patients with ankylosing spondilitis when compared with control group. (p<0,01) Conclusion: Cardiovascular involvement of ankylosing spondilitis is not very common. In this study we have detected statistically significantly lower flow volumes at the rotational sides and total vertebral artery flow volumes in vertebral artery (posterior circulation)of patients with ankylosing spondilitis when compared with healthy controls. But we have not demonstrated such a difference in the carotid artery (anterior circulation) flow volumes at neutral and rotational positions between two groups. We attribute this significant difference in posterior circulation between the groups, to the vertebral artery compression due to vertebral syndesmofitis and enthezopathies are common in patients with ankylosing spondilitis. Furthermore, we think that similar volumes of carotid artery(anterior circulation) in these groups reflects a better protection of anterior circulation haemodynamics with otoregulatory processes. Moreover, we have found a statistically significant increase in carotid artery intimomedial thickness in patients with ankylosing spondilitis when compared with control group.
Objective: The aim of this study is to compare the carotid and vertebral artery flow volumes of the patients with ankylosing spondilitis with age and sex matched controls utilizing the doppler ultrasonography. Material and methods: The patients with comorbid conditions causing atherosclerosis and cerebral arterial flow disturbances, excluded from the study. Finally, a total of 50 patients with ankylosing spondilitis and age/sex matched 50 healthy controls were included in the study. Carotid and vertebral artery flow volumes of all patients and controls were measured by doppler ultrasonography using a 7,5Mhz lineer probe at neutral, left rotational and right rotational pozitions Results: Right vertebral artery and total vertebral artery flow volume at right rotational position, and also left vertebral artery and total vertebral artery flow volume at the left rotational position were found to be statistically significantly lower in patients with ankylosing spondilitis when compared with control group. (p<0,01) Conclusion: Cardiovascular involvement of ankylosing spondilitis is not very common. In this study we have detected statistically significantly lower flow volumes at the rotational sides and total vertebral artery flow volumes in vertebral artery (posterior circulation)of patients with ankylosing spondilitis when compared with healthy controls. But we have not demonstrated such a difference in the carotid artery (anterior circulation) flow volumes at neutral and rotational positions between two groups. We attribute this significant difference in posterior circulation between the groups, to the vertebral artery compression due to vertebral syndesmofitis and enthezopathies are common in patients with ankylosing spondilitis. Furthermore, we think that similar volumes of carotid artery(anterior circulation) in these groups reflects a better protection of anterior circulation haemodynamics with otoregulatory processes. Moreover, we have found a statistically significant increase in carotid artery intimomedial thickness in patients with ankylosing spondilitis when compared with control group.
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Keywords
Radyoloji ve Nükleer Tıp, Ankiloz, Ateroskleroz, Komorbidite, Spondilit-Ankilozan, Ultrasonografi-Doppler, Vertebral Arter, Radiology and Nuclear Medicine, Ankylosis, Atherosclerosis, Comorbidity, Spondylitis-Ankylosing, Ultrasonography-Doppler, Vertebral Artery
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