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Evaluation of the Effect of Primary and Secondary Closure on the Use of Leukocyte and Platelet-Rich Fibrin in Impacted Lower Third Molar Surgery

dc.authorscopusid 58654639800
dc.authorscopusid 55318687000
dc.authorscopusid 59147446100
dc.authorscopusid 58960133500
dc.authorscopusid 59147444900
dc.authorscopusid 58960133600
dc.authorscopusid 58960769200
dc.contributor.author Orhan, Z.D.
dc.contributor.author Ciğerim, L.
dc.contributor.author Güzel, M.
dc.contributor.author Doğru, İ.
dc.contributor.author Alsmadi, M.
dc.contributor.author Kahraman, N.H.
dc.contributor.author Tatar, K.
dc.date.accessioned 2025-05-10T16:55:02Z
dc.date.available 2025-05-10T16:55:02Z
dc.date.issued 2024
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Orhan Z.D., Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Van Yuzuncu Yil, Van, 65090, Turkey; Ciğerim L., Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Van Yuzuncu Yil, Van, 65090, Turkey; Güzel M., Hatay Oral and Dental Health Care Center, Hatay, 31040, Turkey; Doğru İ., Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Van Yuzuncu Yil, Van, 65090, Turkey; Alsmadi M., Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Van Yuzuncu Yil, Van, 65090, Turkey; Kahraman N.H., Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Van Yuzuncu Yil, Van, 65090, Turkey; Hussein A., Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Van Yuzuncu Yil, Van, 65090, Turkey; Tatar K., Department of Prosthodontics, Faculty of Dentistry, University of Van Yuzuncu Yil, Van, 65090, Turkey en_US
dc.description.abstract The aim of this study was to compare the effect of using L-PRF in patients undergoing impacted lower third molar surgery with either primary or secondary closure techniques. Methods: This prospective, randomized, double-blind, split-mouth clinical trial was conducted on patients with bilateral impacted lower third molars of a similar position. Primary closure was performed in group 1 and secondary closure in group 2. The group 1 closure technique was applied to one side of the patients, and the group 2 closure technique was applied to the other side at different times. Of the 45 patients evaluated, 9 patients were excluded from the study because of alveolitis and failure to attend regular control visits out. Results: Of the 36 patients included in the study, 23 were female and 13 were male, with a mean age of 22.42 ± 3.36 years. The secondary closure group had lower VAS scores at hour 6 (p < 0.05). Pain decreased more in the primary closure group when comparing changes between the VAS scores at 6 hours and 7 days (p < 0.05). Conclusions: The results of this study, showing that both secondary and primary closure are effective, with similar outcomes in terms of pain, swelling, and trismus, should be supported by future clinical trials. © 2024 by the authors. en_US
dc.identifier.doi 10.3390/app14104228
dc.identifier.issn 2076-3417
dc.identifier.issue 10 en_US
dc.identifier.scopus 2-s2.0-85194370731
dc.identifier.scopusquality Q3
dc.identifier.uri https://doi.org/10.3390/app14104228
dc.identifier.uri https://hdl.handle.net/20.500.14720/3343
dc.identifier.volume 14 en_US
dc.identifier.wosquality Q2
dc.language.iso en en_US
dc.publisher Multidisciplinary Digital Publishing Institute (MDPI) en_US
dc.relation.ispartof Applied Sciences (Switzerland) en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Closure Techniques en_US
dc.subject Impacted Third Molar en_US
dc.subject Leukocyte And Platelet-Rich Fibrin en_US
dc.subject Primary Closure en_US
dc.subject Regenerative Medicine en_US
dc.subject Secondary Closure en_US
dc.subject Wound Healing en_US
dc.title Evaluation of the Effect of Primary and Secondary Closure on the Use of Leukocyte and Platelet-Rich Fibrin in Impacted Lower Third Molar Surgery en_US
dc.type Article en_US

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