Recurrence of Appendix Tumor: Case Report and Literature Update

Abstract

Herein, we report a case of appendix adenocarcinoma who presented with a recurrence 8 years after the initialdiagnosis. A 54-year-old male underwent appendectomy in 2009. The pathology revealed a 1.7 cm diameterlow grade mucinous carcinoid tumor. Any additional treatment was not recommended for patient other thanappendectomy. The patient was admitted with the symptoms of ileus at 8 years after surgery and then underwentto right hemicolectomy in 2017. On histopathological examination of the specimen revealed a Goblet celladenocarcinoid tumor, arising from iliocecal valv with pericolorectal tissue invasion of 5 cm in diameter.Lymph-node metastases were found in 16 dissected lymph nodes. The patient was initiated to treat withcombined capecitabine and oxaliplatin chemotherapy. There is no clear evidence to support the superiority ofany particular chemotherapy regimen for adjuvant treatment of appendix tumors. In this regard more studiesare needed to use combined regimens.