Hepatoprotective Effect of Foeniculum Vulgare Essential Oil: a Carbon-Tetrachloride Induced Liver Fibrosis Model in Rats
| dc.authorscopusid | 7005912992 | |
| dc.authorscopusid | 25930629300 | |
| dc.authorscopusid | 55560130600 | |
| dc.authorscopusid | 35571490400 | |
| dc.authorscopusid | 7004937377 | |
| dc.authorscopusid | 7103003527 | |
| dc.authorscopusid | 7103003527 | |
| dc.contributor.author | Öbek, H. | |
| dc.contributor.author | Uǧraş, S. | |
| dc.contributor.author | Bayram, I. | |
| dc.contributor.author | Uygan, I. | |
| dc.contributor.author | Erdoǧan, E. | |
| dc.contributor.author | Öztürk, A. | |
| dc.contributor.author | Huyut, Z. | |
| dc.date.accessioned | 2025-05-10T17:51:14Z | |
| dc.date.available | 2025-05-10T17:51:14Z | |
| dc.date.issued | 2004 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | Öbek H., Department of Pharmacology, Faculty of Medicine, Yuzuncu Yil University, 65300 Van, Turkey; Uǧraş S., Department of Pathology, Faculty of Medicine, Yuzuncu Yil University, 65300 Van, Turkey; Bayram I., Department of Pathology, Faculty of Medicine, Yuzuncu Yil University, 65300 Van, Turkey; Uygan I., Department of Gastroenterology, Faculty of Medicine, Yuzuncu Yil University, 65300 Van, Turkey; Erdoǧan E., Department of Histology, Faculty of Medicine, Yuzuncu Yil University, 65300 Van, Turkey; Öztürk A., Department of Pharmacology, Faculty of Medicine, Yuzuncu Yil University, 65300 Van, Turkey; Huyut Z., Department of Pharmacology, Faculty of Medicine, Yuzuncu Yil University, 65300 Van, Turkey | en_US |
| dc.description.abstract | Hepatoprotective activity of Foeniculum vulgare (fennel) essential oil was studied using a carbon tetrachloride-induced liver fibrosis model in rats. The hepatotoxicity produced by chronic carbon tetrachloride administration was found to be inhibited by Foeniculum vulgare essential oil with evidence of decreased levels of serum aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and bilirubin. Histopathological findings also suggest that Foeniculum vulgare essential oil prevents the development of chronic liver damage. The changes in body weights in the rats assigned to the study groups supported these biochemical and histopathological findings. The results of this study clearly indicate that Foeniculum vulgare essential oil has a potent hepatoprotective action against carbon tetrachloride-induced liver fibrosis in rats. | en_US |
| dc.identifier.endpage | 17 | en_US |
| dc.identifier.issn | 0901-3393 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.scopus | 2-s2.0-17144453632 | |
| dc.identifier.scopusquality | Q4 | |
| dc.identifier.startpage | 9 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/18024 | |
| dc.identifier.volume | 31 | en_US |
| dc.identifier.wosquality | Q3 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Scandinavian Journal of Laboratory Animal Science | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Carbon Tetrachloride | en_US |
| dc.subject | Fennel Essential Oil | en_US |
| dc.subject | Feo | en_US |
| dc.subject | Foeniculum Vulgare Miller | en_US |
| dc.subject | Hepatoprotective Effect | en_US |
| dc.subject | Liver Fibrosis | en_US |
| dc.title | Hepatoprotective Effect of Foeniculum Vulgare Essential Oil: a Carbon-Tetrachloride Induced Liver Fibrosis Model in Rats | en_US |
| dc.type | Article | en_US |