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Effects of Clitoria Ternatea on Renal Ischemia and Reperfusion Injury in Rats

dc.authorscopusid 57202435955
dc.authorscopusid 59513304700
dc.authorscopusid 18633524100
dc.authorscopusid 55768911600
dc.authorscopusid 57205673485
dc.authorscopusid 57925656800
dc.authorscopusid 6603924496
dc.contributor.author Melek, Ş.
dc.contributor.author Uyar, A.
dc.contributor.author Akkoyun, H.T.
dc.contributor.author Altun, S.
dc.contributor.author Akkoyun, M.B.
dc.contributor.author Karagözoğlu, F.
dc.contributor.author Bakir, A.
dc.date.accessioned 2025-07-30T16:33:29Z
dc.date.available 2025-07-30T16:33:29Z
dc.date.issued 2025
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Melek Ş.] Bingol Universıty, Faculty of Veterinary Medicine, Department of Surgery, Bingöl, Turkey; [Uyar A.] Hatay Mustafa Kemal University, Faculty of Veterinary Medicine Department of Pathology, Hatay, Turkey; [Akkoyun H.T.] Siirt University, Faculty of Veterinary Medicine, Department of Physiology, Siirt, Turkey; [Altun S.] Ataturk University, Faculty of Veterinary Medicine, Department of Pathology, Erzurum, Turkey; [Akkoyun M.B.] Siirt University, Faculty of Veterinary Medicine, Department of Biochemistry, Siirt, Turkey; [Karagözoğlu F.] Dokuz Eylul University, Faculty of Veterinary Medicine, Department of Anımal Nutrıtıon and Nutritional Diseases, İzmir, Turkey; [Ekin S.] Van Yüzüncü Yıl University, Faculty of Science, Department of Chemistry, Van, Turkey; [Bengü A.Ş.] Van Yüzüncü Yıl University, Faculty of Science, Department of Chemistry, Van, Turkey; [Atalan G.] Erciyes Universıty, Faculty of Veterinary Medicine, Department of Surgery, Kayseri, Turkey; [Bakir A.] YYU University, Faculty of Sciences, Department of Chemistry, Van, Turkey en_US
dc.description.abstract Ischemia-reperfusion (I/R) injury refers to damage caused by the temporary interruption of blood flow into an organ/ tissue and the restoration of circulation. This injury, which affects many vital organs, is still an important clinical and surgical problem. This study aims to investigate the effect of antioxidant and anti-inflammatory effects of Clitoria ternatea on renal I/R injury in rats. Twenty-four male Wistar albino rats were clustered into 4 groups, 6 rats in each (Control, I/R group, Clitoria ternatea group, I/R group + Clitoria ternatea group). At the end of the experimental procedures, all groups were euthanised in accordance with ethical rules. Blood and tissue samples were taken and subsequent biochemical (MDA, SOD, CAT, GSH-Px, BUN, Na, K, creatine), histopathological and immunohistochemical analyses demonstrated that Clitoria ternatea effectively prevented I/R-induced renal injury in rats. Based on these findings, Clitoria ternatea may be considered a potential therapeutic agent for the prevenstion of I/R-induced kidney damage. © (2025), (Universidad del Zulia, Facultad de Ciencias Veterinarias). All rights reserved. en_US
dc.identifier.doi 10.52973/rcfcv-e35657
dc.identifier.endpage 8 en_US
dc.identifier.issn 0798-2259
dc.identifier.issue 2 en_US
dc.identifier.scopus 2-s2.0-105009966018
dc.identifier.scopusquality Q4
dc.identifier.startpage 1 en_US
dc.identifier.uri https://doi.org/10.52973/rcfcv-e35657
dc.identifier.uri https://hdl.handle.net/20.500.14720/28116
dc.identifier.volume 35 en_US
dc.identifier.wosquality Q4
dc.language.iso en en_US
dc.publisher Universidad del Zulia, Facultad de Ciencias Veterinarias en_US
dc.relation.ispartof Revista Cientifica de la Facultad de Veterinaria en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Clitoria Ternatea en_US
dc.subject Clitoria Ternatea en_US
dc.subject Ischemia-Reperfusion en_US
dc.subject Isquemia-Reperfusión en_US
dc.subject Rat en_US
dc.subject Rata en_US
dc.subject Riñóln en_US
dc.subject Terapeutico en_US
dc.subject Therpeutic en_US
dc.title Effects of Clitoria Ternatea on Renal Ischemia and Reperfusion Injury in Rats en_US
dc.title.alternative Efectos De La Clitoria Ternatea En La Lesó Renal Por Isquemia Y Repefusión En Ratas en_US
dc.type Article en_US

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