The Effects of Protein Deficiency on Na, K-Atpase Activity in Rat Kidney

Abstract

The aim of the study was to evaluate the effects of protein deficiency on renal Na, K-ATPase activity and cholesterol levels in rats. Wistar rats were used in the study and were fed with a diet variously containing 3%, 12.5% and 25% protein. The results showed that body weight gains in protein deficient groups were lower than control group. Renal Na, K-ATPase activity was significantly higher in control than the protein deficient groups especially in 30 and 45th days (P < 0.05). Renal cholesterol concentrations were significantly lower in both protein deficient groups than in control rats. The results of this study clearly show that protein deficiency in male rats affects renal Na, K-ATPase activity.