Study on Dna Binding Properties of Nickle (Ii) Phthalocyanine Compound With 2-Isopropyl Methylphenoxy Substituents
| dc.contributor.author | Arslantaş, Ali | |
| dc.contributor.author | Agirtas, M. Salih | |
| dc.date.accessioned | 2025-05-10T17:15:45Z | |
| dc.date.available | 2025-05-10T17:15:45Z | |
| dc.date.issued | 2017 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | Karabük Üni̇versi̇tesi̇,Van Yüzüncü Yil Üni̇versi̇tesi̇ | en_US |
| dc.description.abstract | I n this study, previously synthesized Ni (II) phthalocyanine compound bearing 2,10,16,24-tetrakis(2-isopropyl-5-methylphenoxy group was chosen for its interaction with calf thymus-DNA. Calf thymus-DNA was used to determine DNA binding properties of Ni (II) phthalocyanine compound. The DNA binding activities of Ni (II) phthalocyanine compound bearing 2-isopropyl-5-methylphenoxy substituent was investigated by using absorption titration, fluorescence emission, cyclic voltammetry, gel elctrophoresis in Tris-HCl buffer at pH 7.0. In addition to above methods, melting point and viscosity experiment were performed to determine the DNA intercation of the compound in Tris-HCl buffer solution. The results showed that Ni (II) phthalocyanine compound binds strongly to calf thymus-DNA via intercalation binding | en_US |
| dc.identifier.endpage | 97 | en_US |
| dc.identifier.issn | 2149-2123 | |
| dc.identifier.issn | 2148-4171 | |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.scopusquality | N/A | |
| dc.identifier.startpage | 91 | en_US |
| dc.identifier.trdizinid | 271564 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/en/yayin/detay/271564/study-on-dna-binding-properties-of-nickle-ii-phthalocyanine-compound-with-2-isopropyl-5-methylphenoxy-substituents | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/8748 | |
| dc.identifier.volume | 4 | en_US |
| dc.identifier.wosquality | N/A | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Hittite Journal of Science and Engineering | en_US |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Biyoloji | en_US |
| dc.subject | Kimya | en_US |
| dc.subject | Tıbbi | en_US |
| dc.subject | Biyokimya Ve Moleküler Biyoloji | en_US |
| dc.title | Study on Dna Binding Properties of Nickle (Ii) Phthalocyanine Compound With 2-Isopropyl Methylphenoxy Substituents | en_US |
| dc.type | Article | en_US |