Antioxidant Activities (superoxide Dismutase, Catalase, Reduced Glutation) and Oxidative Stress (malondialdehyde) Levels in Individuals Successed With Covid-19 Disease
Abstract
Bu tez çalışmasında S.B.Ü. Van Bölge Eğitim ve Araştırma Hastanesi Covid-19 servisi ve Göğüs Hastalıkları Servisi'ne başvuran ve Covid-19 tanısı konulan hastalardan alınan serum örneklerinden bazı antioksidan aktiviteleri (SOD, CAT ve GSH) ile oksidatif stres (MDA) düzeyleri tayin edildi. Yapılan bu tez çalışmasında Covid-19 olan hastalarda SOD, CAT ve GSH aktiviteleri, sağlıklı kontrol grubu ile kıyaslandığında daha düşük bulundu (p<0.05). Hasta grubun serum MDA düzeyi kontrol grubu ile kıyaslandığında daha yüksek bulundu (p<0.05). Sonuç olarak; SOD, CAT ve GSH aktivitelerinin hastaların kanında düşük, serum MDA düzeyinin ise yüksek oluşu, Covid-19 hastalığını ağır geçirme riskini arttırıcı faktörü olarak değerlendirilebilir.
This thesis in his work SBU. Van Region Education and Research Hospital Covid-19 service and Chest Diseases to your service applicant and the diagnosis of Covid-19 placed from patients from serum samples. Some antioxidant activities (SOD, CAT, and GSH) oxidative stress (MDA) levels ration was done. Made this thesis with Covid-19 in the study in patients the one which SOD, CAT, GSH activities in patients , healthy control to the group by more low found (p<0.05). Patient serum MDA level of the group control to the group by more high school found (p<0.05). Conclusion as; SOD, CAT and GSH activities of patients in blood low, serum MDA level if high can be considered as an increasing factor in the risk of severe Covid-19 disease.
This thesis in his work SBU. Van Region Education and Research Hospital Covid-19 service and Chest Diseases to your service applicant and the diagnosis of Covid-19 placed from patients from serum samples. Some antioxidant activities (SOD, CAT, and GSH) oxidative stress (MDA) levels ration was done. Made this thesis with Covid-19 in the study in patients the one which SOD, CAT, GSH activities in patients , healthy control to the group by more low found (p<0.05). Patient serum MDA level of the group control to the group by more high school found (p<0.05). Conclusion as; SOD, CAT and GSH activities of patients in blood low, serum MDA level if high can be considered as an increasing factor in the risk of severe Covid-19 disease.
Description
Keywords
Kimya, Antioksidan aktivite, Antioksidanlar, COVID 19, Katalaz, Oksidatif stres, Redükte glutatyon, Chemistry, Antioxidant activity, Antioxidants, COVID 19, Catalase, Oxidative stress, Reduced glutathione
Turkish CoHE Thesis Center URL
WoS Q
Scopus Q
Source
Volume
Issue
Start Page
End Page
109