Chemical Constituents and Antibacterial Activities of Essential Oils of Common Mugwort (Artemisia Vulgaris L.) From Eastern Anatolia Flora

Abstract

The essential oil components of common mugwort (Artemisia vulgaris L.) and their antibacterial activity were analyzed in the present study. Aerial parts of A. vulgaris plants were collected from natural habitats from Van region of Turkey. Essential oils were isolated using the hydro-distillation method and their components were analyzed by gas chromatography-mass spectrometry (GC-MS). The major components found in essential oil of common mugwort were thujone (60.28%), caryophyllene oxide (11.46%), α-Thujone (9.46%), 1.8 cineole (5.06%), trans-caryophyllene (3.57) and linalool (3.40%). Antibacterial activity of the essential oil was designated against six microorganisms using the disc diffusion method. Essential oils of A. vulgaris extracts were screened for antibacterial activity against three gram-negative (Pseudomonas aeruginosa, Salmonella typhimurium and Escherichia coli) and three gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis and Enterecoccus faecalis). The results illustrated that the essential oils of common mugwort were sensitive; inhibition zones differed to various bacteria such as Escherichia coli ATCC 11775 (14-14 mm), Salmonella typhimurium ATCC 25241 (13-14 mm), Enterecoccus faecalis ATCC 29212 (12-13 mm), Bacillus subtilis ATCC 6051 (12-12 mm), Pseudomonas aeruginosa ATCC 10145 (11-11 mm) and Staphylococcus aureus ATCC 12600 (10-11 mm). The presented results may open new avenues for the development of new phytotherapeutic products from the common mugwort plant species.