A Case of Leukocytoclastic Vasculitis With Membranoproliferative Glomerulonephritis

Abstract

Henoch-Schonlein purpura is the most common vasculitis in childhood with the pathogenesis of immunoglobulin A deposition in small-vessel wall. As the end-organ vasculature involved, this disease is characterized by palpable purpura, abdominal pain, arthritis, and renal disease. Renal involvement may present with isolated haematuria and/or proteinuria from mild to severe as nephrotic levels. Membranoproliferative glomerulonephritis is the most common cause of chronic glomerulonephritis in older children and young adults and also one of the major causes of nephrotic syndrome. In this case, we reported the concurrent of leukocytoclastic vasculitis with membranoproliferative glomerulonephritis.