Evaluation of Metabolic Syndrome Prevalence and Parameters in Patients With Fibromyalgia

Abstract

Objectives: We aimed to evaluate the metabolic syndrome (MetS) parameters in patients with fibromyalgiasyndrome.Methods: Age, weight, height, body mass index, waist and hip circumferences, and blood pressure were recorded. Laboratory parameters included fasting blood glucose and insulin, high-density lipoprotein, and triglyceride, HOMA-IR.Results: Thirty-five female patients aged 20-64 years with fibromyalgia and 29 age-matched healthy controlswere included in this case-control study. Although MetS was more prevalent in fibromyalgia patients than thecontrol group, the difference did not reach a statistically significant level [7 (20.0%) vs. 5 (17.2%), p=0.770]. Theprevalence of high waist circumference was significantly higher in the fibromyalgia group than the controlgroup [23 (65.7%) vs. 6 (20.7%), p<0.001]. High blood pressure was also more prevalent in fibromyalgia group[10 (28.6%) vs. 1 (3.4%), p=0.009]. Insulin resistance and dyslipidemia prevalence did not show a significantdifference between groups (p=0.830 and p=0.250, respectively).Conclusion: Although statistically insignificant, metabolic prevalence increases in patients with fibromyalgia,while some MetS parameters, including waist circumference, and systolic and diastolic blood pressures, weresignificantly higher in fibromyalgia. Therefore, fibromyalgia patients may be under greater risk of MetS thanthe general population. For a definitive conclusion on the MetS and fibromyalgia, further large-scale studiesare needed.