Synthesis of Triazole-Coupled Quinoline-Based Fluorescent Sensor

Abstract

Fluorescent sensor is one of the most important chemical sensors and is a powerful tool for imaging target molecules and ions in the living organism. Because it has high sensitivity and simultaneous imaging. In this work, fluorescence chemosensor was designed based on ionophore-bridge-fluorophore approach. In the structure of the designed chemosensor, anthracene unit was used as fluorophore. The receptoric hydroxy quinoline group to interact with the metal ion were incorporated into the structure by the triazole bridge which has high coordination properties. Detection of a specific type of a metal is very important in terms of biouse of the related compound. In addition to the synthetic approach, the metal coordination propertiess of the novel chemosensors will be investigated theoretically at the level of Density Functional theory with the application of B3LYP/6-31++G(d,p), which is a combination of hibrit exchange function and basis set. © 2024, ISRES Publishing. All rights reserved.