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Paraoxonase and Prolidase Activity in Patietns With Malignant Gliomas

dc.authorid Cebi, Aysegul/0000-0003-3804-7966
dc.authorscopusid 55554281100
dc.authorscopusid 16550585500
dc.authorscopusid 36608131400
dc.authorscopusid 57158783300
dc.authorscopusid 36096565100
dc.authorscopusid 21333559300
dc.authorscopusid 26026823300
dc.authorwosid Gonullu, Hayriye/Aau-9606-2021
dc.authorwosid Gönüllü, Edip/Aav-7377-2021
dc.authorwosid Çebi, Ayşegül/L-2854-2019
dc.contributor.author Gonullu, Edip
dc.contributor.author Silav, Gokalp
dc.contributor.author Kaya, Miktat
dc.contributor.author Arslan, Mehmet
dc.contributor.author Gonullu, Hayriye
dc.contributor.author Arslan, Harun
dc.contributor.author Demir, Halit
dc.date.accessioned 2025-05-10T17:46:40Z
dc.date.available 2025-05-10T17:46:40Z
dc.date.issued 2012
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Gonullu, Hayriye] Yuzuncu Yil Univ, Tip Fak, Acil Tip Anabilim Dali, Van, Turkey; [Gonullu, Edip] Van Bolge Egitim & Arastirma Hastanesi, Anestezi & Reanimasyon Klin, Van, Turkey; [Demir, Halit] Yuzuncu Yil Univ, Tip Fak, Biyokimya Anabilim Dali, Van, Turkey; [Kaya, Miktat] Kafkas Univ, Tip Fak, Beyin Cerrahisi Anabilim Dali, Kars, Turkey; [Arslan, Mehmet] Yuzuncu Yil Univ, Tip Fak, Beyin Cerrahisi Anabilim Dali, Van, Turkey; [Arslan, Harun] Van Bolge Egitim & Arastirma Hastanesi, Radyol Klin, Van, Turkey; [Cebi, Aysegul] Giresun Univ, Sagl Bilimleri Fak, Giresun, Turkey; [Silav, Gokalp] Acibadem Univ, Beyin Cerrahisi Klin, Istanbul, Turkey en_US
dc.description Cebi, Aysegul/0000-0003-3804-7966 en_US
dc.description.abstract Aim: We aimed to determine the relationship both paraoxonase and prolidase activitys in the patients with malignant glioma. Methods: In this study, serum paraoxonase and prolidase activitys were measured on 25 healthy human and 25 patients with malignant glioma. Paraoxonase activity was measured using diethyl-p-nitrophenylphosphate as substrate, as previously described. The prolidase activity was used for measurement of proline by the method proposed by Myara et al., which is a modification of Chinard's method (Myara et al., 1982). Results: The paraoxonase and prolidase activitys were significantly lower in serum of patients with malignant glioma as a whole compared to controls. Conclusions: In the current study, the activity paraoxonase and prolidase decreased in the patients with malignant glioma. As a result the paraoxonase and prolidase decreased seems to play a major role in the pathophysiology of malignant glioma. This is the first report on serum paraoxonase and prolidase decreased activities in patients with malignant gliomas. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.endpage 782 en_US
dc.identifier.issn 1302-1664
dc.identifier.issue 4 en_US
dc.identifier.scopus 2-s2.0-84872258910
dc.identifier.scopusquality N/A
dc.identifier.startpage 778 en_US
dc.identifier.uri https://hdl.handle.net/20.500.14720/16784
dc.identifier.volume 29 en_US
dc.identifier.wos WOS:000312600000012
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Journal Neurological Sciences en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Malignant Glioma en_US
dc.subject Paraoxonase Activity en_US
dc.subject Prolidase Activity en_US
dc.title Paraoxonase and Prolidase Activity in Patietns With Malignant Gliomas en_US
dc.type Article en_US

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