Paraoxonase and Prolidase Activity in Patietns With Malignant Gliomas
dc.authorid | Cebi, Aysegul/0000-0003-3804-7966 | |
dc.authorscopusid | 55554281100 | |
dc.authorscopusid | 16550585500 | |
dc.authorscopusid | 36608131400 | |
dc.authorscopusid | 57158783300 | |
dc.authorscopusid | 36096565100 | |
dc.authorscopusid | 21333559300 | |
dc.authorscopusid | 26026823300 | |
dc.authorwosid | Gonullu, Hayriye/Aau-9606-2021 | |
dc.authorwosid | Gönüllü, Edip/Aav-7377-2021 | |
dc.authorwosid | Çebi, Ayşegül/L-2854-2019 | |
dc.contributor.author | Gonullu, Edip | |
dc.contributor.author | Silav, Gokalp | |
dc.contributor.author | Kaya, Miktat | |
dc.contributor.author | Arslan, Mehmet | |
dc.contributor.author | Gonullu, Hayriye | |
dc.contributor.author | Arslan, Harun | |
dc.contributor.author | Demir, Halit | |
dc.date.accessioned | 2025-05-10T17:46:40Z | |
dc.date.available | 2025-05-10T17:46:40Z | |
dc.date.issued | 2012 | |
dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
dc.department-temp | [Gonullu, Hayriye] Yuzuncu Yil Univ, Tip Fak, Acil Tip Anabilim Dali, Van, Turkey; [Gonullu, Edip] Van Bolge Egitim & Arastirma Hastanesi, Anestezi & Reanimasyon Klin, Van, Turkey; [Demir, Halit] Yuzuncu Yil Univ, Tip Fak, Biyokimya Anabilim Dali, Van, Turkey; [Kaya, Miktat] Kafkas Univ, Tip Fak, Beyin Cerrahisi Anabilim Dali, Kars, Turkey; [Arslan, Mehmet] Yuzuncu Yil Univ, Tip Fak, Beyin Cerrahisi Anabilim Dali, Van, Turkey; [Arslan, Harun] Van Bolge Egitim & Arastirma Hastanesi, Radyol Klin, Van, Turkey; [Cebi, Aysegul] Giresun Univ, Sagl Bilimleri Fak, Giresun, Turkey; [Silav, Gokalp] Acibadem Univ, Beyin Cerrahisi Klin, Istanbul, Turkey | en_US |
dc.description | Cebi, Aysegul/0000-0003-3804-7966 | en_US |
dc.description.abstract | Aim: We aimed to determine the relationship both paraoxonase and prolidase activitys in the patients with malignant glioma. Methods: In this study, serum paraoxonase and prolidase activitys were measured on 25 healthy human and 25 patients with malignant glioma. Paraoxonase activity was measured using diethyl-p-nitrophenylphosphate as substrate, as previously described. The prolidase activity was used for measurement of proline by the method proposed by Myara et al., which is a modification of Chinard's method (Myara et al., 1982). Results: The paraoxonase and prolidase activitys were significantly lower in serum of patients with malignant glioma as a whole compared to controls. Conclusions: In the current study, the activity paraoxonase and prolidase decreased in the patients with malignant glioma. As a result the paraoxonase and prolidase decreased seems to play a major role in the pathophysiology of malignant glioma. This is the first report on serum paraoxonase and prolidase decreased activities in patients with malignant gliomas. | en_US |
dc.description.woscitationindex | Science Citation Index Expanded | |
dc.identifier.endpage | 782 | en_US |
dc.identifier.issn | 1302-1664 | |
dc.identifier.issue | 4 | en_US |
dc.identifier.scopus | 2-s2.0-84872258910 | |
dc.identifier.scopusquality | N/A | |
dc.identifier.startpage | 778 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.14720/16784 | |
dc.identifier.volume | 29 | en_US |
dc.identifier.wos | WOS:000312600000012 | |
dc.identifier.wosquality | N/A | |
dc.language.iso | en | en_US |
dc.publisher | Journal Neurological Sciences | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Malignant Glioma | en_US |
dc.subject | Paraoxonase Activity | en_US |
dc.subject | Prolidase Activity | en_US |
dc.title | Paraoxonase and Prolidase Activity in Patietns With Malignant Gliomas | en_US |
dc.type | Article | en_US |