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6-Methylthiouracil and 6-Methyluracil Derivatives Synthesized by Reaction of Acetylketene With Thiourea and Urea Compounds in Presence of Yb(Tfa)3

dc.authorid Aslanoglu, Furgan/0000-0002-5740-1716
dc.authorscopusid 12241099400
dc.authorscopusid 58529905800
dc.authorwosid Aslanoglu, Furgan/D-8014-2019
dc.contributor.author Aslanoglu, Furgan
dc.contributor.author Yazici, Ahmet
dc.date.accessioned 2025-05-10T17:18:26Z
dc.date.available 2025-05-10T17:18:26Z
dc.date.issued 2023
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Aslanoglu, Furgan; Yazici, Ahmet] Van Yuzuncu Yil Univ, Dept Chem, Van, Turkiye en_US
dc.description Aslanoglu, Furgan/0000-0002-5740-1716 en_US
dc.description.abstract Thiouracil and uracil derivatives are among the bioactive molecules used in the treatment of many diseases, such as 6-propylthiouracil and 5-fluorouracil. A new synthesis method of 6-methylthiouracil and 6-methyluracil was developed in this study. Various 6-methylthiouracil and 6-methyluracil derivatives were obtained by reacting 2,2,6-trimethyl-4H-1,3-dioxin-4-one with thiourea and urea compounds in the presence of Yb(TFA)(3) according to this new method. Optimization of this new method was performed. The structures of 6-methylthiouracil and 6-methyluracil derivatives were characterized. en_US
dc.description.sponsorship Van Yuzuncu Yil University [FBA-2022-10288] en_US
dc.description.sponsorship This work was supported by Van Yuzuncu Yil University under Grant [FBA-2022-10288]. en_US
dc.description.woscitationindex Science Citation Index Expanded - Index Chemicus - Current Chemical Reactions
dc.identifier.doi 10.1080/00397911.2023.2245506
dc.identifier.endpage 1721 en_US
dc.identifier.issn 0039-7911
dc.identifier.issn 1532-2432
dc.identifier.issue 20 en_US
dc.identifier.scopus 2-s2.0-85167513880
dc.identifier.scopusquality Q2
dc.identifier.startpage 1713 en_US
dc.identifier.uri https://doi.org/10.1080/00397911.2023.2245506
dc.identifier.uri https://hdl.handle.net/20.500.14720/9684
dc.identifier.volume 53 en_US
dc.identifier.wos WOS:001044063000001
dc.identifier.wosquality Q3
dc.language.iso en en_US
dc.publisher Taylor & Francis inc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject 2 en_US
dc.subject 6-Trimethyl-4H-1 en_US
dc.subject 3-Dioxin-4-One en_US
dc.subject 6-Methylthiouracil en_US
dc.subject 6-Methyluracil en_US
dc.subject Yb(Tfa)(3) en_US
dc.subject > en_US
dc.title 6-Methylthiouracil and 6-Methyluracil Derivatives Synthesized by Reaction of Acetylketene With Thiourea and Urea Compounds in Presence of Yb(Tfa)3 en_US
dc.type Article en_US

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