6-Methylthiouracil and 6-Methyluracil Derivatives Synthesized by Reaction of Acetylketene With Thiourea and Urea Compounds in Presence of Yb(Tfa)3
dc.authorid | Aslanoglu, Furgan/0000-0002-5740-1716 | |
dc.authorscopusid | 12241099400 | |
dc.authorscopusid | 58529905800 | |
dc.authorwosid | Aslanoglu, Furgan/D-8014-2019 | |
dc.contributor.author | Aslanoglu, Furgan | |
dc.contributor.author | Yazici, Ahmet | |
dc.date.accessioned | 2025-05-10T17:18:26Z | |
dc.date.available | 2025-05-10T17:18:26Z | |
dc.date.issued | 2023 | |
dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
dc.department-temp | [Aslanoglu, Furgan; Yazici, Ahmet] Van Yuzuncu Yil Univ, Dept Chem, Van, Turkiye | en_US |
dc.description | Aslanoglu, Furgan/0000-0002-5740-1716 | en_US |
dc.description.abstract | Thiouracil and uracil derivatives are among the bioactive molecules used in the treatment of many diseases, such as 6-propylthiouracil and 5-fluorouracil. A new synthesis method of 6-methylthiouracil and 6-methyluracil was developed in this study. Various 6-methylthiouracil and 6-methyluracil derivatives were obtained by reacting 2,2,6-trimethyl-4H-1,3-dioxin-4-one with thiourea and urea compounds in the presence of Yb(TFA)(3) according to this new method. Optimization of this new method was performed. The structures of 6-methylthiouracil and 6-methyluracil derivatives were characterized. | en_US |
dc.description.sponsorship | Van Yuzuncu Yil University [FBA-2022-10288] | en_US |
dc.description.sponsorship | This work was supported by Van Yuzuncu Yil University under Grant [FBA-2022-10288]. | en_US |
dc.description.woscitationindex | Science Citation Index Expanded - Index Chemicus - Current Chemical Reactions | |
dc.identifier.doi | 10.1080/00397911.2023.2245506 | |
dc.identifier.endpage | 1721 | en_US |
dc.identifier.issn | 0039-7911 | |
dc.identifier.issn | 1532-2432 | |
dc.identifier.issue | 20 | en_US |
dc.identifier.scopus | 2-s2.0-85167513880 | |
dc.identifier.scopusquality | Q2 | |
dc.identifier.startpage | 1713 | en_US |
dc.identifier.uri | https://doi.org/10.1080/00397911.2023.2245506 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14720/9684 | |
dc.identifier.volume | 53 | en_US |
dc.identifier.wos | WOS:001044063000001 | |
dc.identifier.wosquality | Q3 | |
dc.language.iso | en | en_US |
dc.publisher | Taylor & Francis inc | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | 2 | en_US |
dc.subject | 6-Trimethyl-4H-1 | en_US |
dc.subject | 3-Dioxin-4-One | en_US |
dc.subject | 6-Methylthiouracil | en_US |
dc.subject | 6-Methyluracil | en_US |
dc.subject | Yb(Tfa)(3) | en_US |
dc.subject | > | en_US |
dc.title | 6-Methylthiouracil and 6-Methyluracil Derivatives Synthesized by Reaction of Acetylketene With Thiourea and Urea Compounds in Presence of Yb(Tfa)3 | en_US |
dc.type | Article | en_US |