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In Vitro Enzyme Inhibitory Activity of Ten Ferulago W. Koch Species Growing in Turkey

dc.authorid Kupeli Akkol, Esra/0000-0002-5829-7869
dc.authorid Kilic, Ceyda Sibel/0000-0003-2905-7628
dc.authorid Gurbuz, Ilhan/0000-0002-3670-0899
dc.authorid Gunbatan, Tugba/0000-0002-1138-3145
dc.authorscopusid 23096992900
dc.authorscopusid 57188819718
dc.authorscopusid 6602792411
dc.authorscopusid 7006403338
dc.authorscopusid 6507159905
dc.authorscopusid 56020070400
dc.authorwosid Akkol, Esra/Abi-4678-2020
dc.authorwosid Günbatan, Tuğba/Aha-9058-2022
dc.authorwosid Gurbuz, Ilhan/Ahb-3295-2022
dc.authorwosid Ilhan, Mert/Hlh-6199-2023
dc.authorwosid Kilic, Ceyda Sibel/F-8057-2014
dc.contributor.author Akkol, Esra Kupeli
dc.contributor.author Gunbatan, Tugba
dc.contributor.author Gurbuz, Ilhan
dc.contributor.author Duman, Hayri
dc.contributor.author Kilic, Ceyda Sibel
dc.contributor.author Ilhan, Mert
dc.date.accessioned 2025-05-10T17:13:56Z
dc.date.available 2025-05-10T17:13:56Z
dc.date.issued 2022
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Akkol, Esra Kupeli; Gunbatan, Tugba; Gurbuz, Ilhan] Gazi Univ, Fac Pharm, Dept Pharmacognosy, Ankara, Turkey; [Duman, Hayri] Gazi Univ, Fac Sci, Dept Biol, Ankara, Turkey; [Kilic, Ceyda Sibel] Ankara Univ, Fac Pharm, Dept Pharmaceut Bot, Ankara, Turkey; [Ilhan, Mert] Van Yuzuncu Yil Univ, Fac Pharm, Dept Pharmacognosy, Van, Turkey en_US
dc.description Kupeli Akkol, Esra/0000-0002-5829-7869; Kilic, Ceyda Sibel/0000-0003-2905-7628; Gurbuz, Ilhan/0000-0002-3670-0899; Gunbatan, Tugba/0000-0002-1138-3145 en_US
dc.description.abstract Ferulago species are traditionally used for the treatment of skin diseases, bronchitis, and depression, to increase body strength, as an immunostimulant, aphrodisiac and sedative in Anatolia. In this study, hyaluronidase, collagenase and elastase inhibitory potential relevant to wound healing activities of ethanol extracts from the roots of ten Ferulago species [F. cassia Boiss., F. humilis Boiss., F. isaurica Pesmen, F. longistylis Boiss., F. mascrosciadia Boiss. & Balansa, F. sandrasica Pesmen & Quezel, F. setifolia K. Koch., F. silaifolia (Boiss.) Boiss., F. trojana Akalin & Pimenov formerly known as F. sylvatica (Besser) Rchb. and F. syriaca Boiss.] were investigated. Ethanol extracts of F. mascrosciadia and F. syriaca were the most active ones against collagenase and elastase, respectively. In vitro wound healing activity of ten Ferulago species is reported for the first time in the current study. en_US
dc.description.sponsorship TUBITAK [115S364] en_US
dc.description.sponsorship This research was partially funded by TUBITAK (115S364). en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1590/1678-4324-2022210207
dc.identifier.issn 1516-8913
dc.identifier.issn 1678-4324
dc.identifier.scopus 2-s2.0-85131420385
dc.identifier.scopusquality Q2
dc.identifier.uri https://doi.org/10.1590/1678-4324-2022210207
dc.identifier.uri https://hdl.handle.net/20.500.14720/8344
dc.identifier.volume 65 en_US
dc.identifier.wos WOS:000820488800001
dc.identifier.wosquality Q4
dc.language.iso en en_US
dc.publisher inst Tecnologia Parana en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Ferulago en_US
dc.subject Collagenase en_US
dc.subject Elastase en_US
dc.subject Hyaluronidase en_US
dc.subject Wound en_US
dc.title In Vitro Enzyme Inhibitory Activity of Ten Ferulago W. Koch Species Growing in Turkey en_US
dc.type Article en_US

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