The Effect of Coq10 and Vitamin E on Serum Total Sialic Acid, Lipid-Bound Sialic Acid, Some Trace Elements and Minerals in Rats Induced With Doxorubicin
| dc.authorid | Ekin, Suat/0000-0002-6502-5028 | |
| dc.authorid | Yasar, Semih/0000-0002-2149-405X | |
| dc.authorid | Yasar, Semih/0000-0003-2754-6030 | |
| dc.authorid | Ozdemir, Hulya/0000-0002-6045-8342 | |
| dc.authorscopusid | 25230277800 | |
| dc.authorscopusid | 6602257873 | |
| dc.authorscopusid | 23471490500 | |
| dc.authorscopusid | 7004290487 | |
| dc.authorscopusid | 6603102677 | |
| dc.authorwosid | Ekin, Suat/Aar-2193-2020 | |
| dc.authorwosid | Yaåÿar, Semih/V-6402-2019 | |
| dc.contributor.author | Oto, Gokhan | |
| dc.contributor.author | Ekin, Suat | |
| dc.contributor.author | Yasar, Semih | |
| dc.contributor.author | Ozdemir, Hulya | |
| dc.contributor.author | Yur, Fatmagul | |
| dc.date.accessioned | 2025-05-10T17:48:31Z | |
| dc.date.available | 2025-05-10T17:48:31Z | |
| dc.date.issued | 2011 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Oto, Gokhan; Ozdemir, Hulya] Yuzuncu Yil Univ, Fac Med, Dept Pharmacol, Van, Turkey; [Ekin, Suat] Yuzuncu Yil Univ, Fac Arts & Sci, Dept Biochem, Van, Turkey; [Yasar, Semih] Bingol Univ, Fac Arts & Sci, Dept Biochem, Bingol, Turkey; [Yur, Fatmagul] Yuzuncu Yil Univ, Fac Vet, Dept Biochem, Van, Turkey | en_US |
| dc.description | Ekin, Suat/0000-0002-6502-5028; Yasar, Semih/0000-0002-2149-405X; Yasar, Semih/0000-0003-2754-6030; Ozdemir, Hulya/0000-0002-6045-8342 | en_US |
| dc.description.abstract | This study was designed to evaluate the effect of CoQ(10) and vitamin E on serum total sialic acid (TSA), lipid bound sialic acid (LSA) and some elements in rat administered doxorubicin (DXR). Cu levels were increased in the group treated with DXR + vitamin E in comparison with DXR (p<0.05) and CoQ(10) groups (p = 0.001). Furthermore, copper levels were increased in the group treated with DXR + CoQ10 in comparison with CoQ(10) group (p < 0.05). Zn levels were decreased in the group treated with DXR + vitamin E in comparison with CoQ(10) group (p < 0.05). Mg levels were decreased in subjects treated with DXR + vitamin E in comparison with the control group values (p < 0.05). Particularly, the observed increase in Cu levels in rats from DXR + vitamin E group might be due to the decrease of vitamin E. However, the oxidative damage could be as a result of DXR occurence and may be helpful to clinicians in chemotherapy using anthracycline. | en_US |
| dc.description.sponsorship | Scientific Research Projects Presidency of Yuzuncu Yil University [2007-SBE-YL104] | en_US |
| dc.description.sponsorship | This study was supported by a grant from the Scientific Research Projects Presidency of Yuzuncu Yil University (2007-SBE-YL104). | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded | |
| dc.identifier.endpage | 5224 | en_US |
| dc.identifier.issn | 1684-5315 | |
| dc.identifier.issue | 26 | en_US |
| dc.identifier.scopus | 2-s2.0-79959336037 | |
| dc.identifier.scopusquality | N/A | |
| dc.identifier.startpage | 5219 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/17115 | |
| dc.identifier.volume | 10 | en_US |
| dc.identifier.wos | WOS:000294614000019 | |
| dc.identifier.wosquality | N/A | |
| dc.language.iso | en | en_US |
| dc.publisher | Academic Journals | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Doxorubicin | en_US |
| dc.subject | Total Sialic Acid (Tsa) | en_US |
| dc.subject | Lipid Bound Sialic Acid (Lsa) | en_US |
| dc.subject | Trace Elements | en_US |
| dc.subject | Minerals | en_US |
| dc.title | The Effect of Coq10 and Vitamin E on Serum Total Sialic Acid, Lipid-Bound Sialic Acid, Some Trace Elements and Minerals in Rats Induced With Doxorubicin | en_US |
| dc.type | Article | en_US |