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Correlation of Cervical Smear Cytology and Histopathology Findings From Van Yüzüncü Yıl University Dursun Odabaş Medical Center in Turkey

dc.authorscopusid 57215432279
dc.authorscopusid 24461417500
dc.authorscopusid 57193379219
dc.authorscopusid 55560130600
dc.contributor.author Demir, F.
dc.contributor.author Erten, R.
dc.contributor.author Aras, İ.
dc.contributor.author Bayram, İ.
dc.date.accessioned 2025-05-10T17:02:16Z
dc.date.available 2025-05-10T17:02:16Z
dc.date.issued 2020
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Demir F., Van Yüzüncü Yıl University, Faculty of Medicine, Department of Medical Pathology, Van, Turkey; Erten R., Van Yüzüncü Yıl University, Faculty of Medicine, Department of Medical Pathology, Van, Turkey; Aras İ., Van Yüzüncü Yıl University, Faculty of Medicine, Department of Medical Pathology, Van, Turkey; Bayram İ., Van Yüzüncü Yıl University, Faculty of Medicine, Department of Medical Pathology, Van, Turkey en_US
dc.description.abstract Papanicolaou cytology (Pap smear) is a screening technique recommended by World Health Organization (WHO), commonly used in the detection of precancerous lesions. This study aimed to compare the Pap smear results and the subsequent biopsy results in 258 patients diagnosed in our clinic to analyse their false-positive and false-negative rates and to discuss the outcomes in light of literature. The study included Pap smear specimens archived for four years that had undergone histopatholojical diagnoses of cervical biopsy, conization, curettage, and/or histerectomy within the three months. In the retrospective analysis, cytological diagnosis and the histological diagnosis which had been established within the subsequent three months were compared and then the false-negative and false-positive rates were calculated. In the cyto-histological comparison, the false-negative and false-positive rates independent of class ratio were 4,3% and 19%, respectively. The sensitivity, selectivity, positive and negative predictive values were 69%, 98%, 89% and 93%, respectively, excluding atypical classes of the cytologic diagnoses. As can be seen in our results, the correlation between Pap smear and biopsy results in our patients displayed an unignorable inconsistency although it was not remarkably different from those reported in the literature. Such discrepancies, which are likely to be detected in the cyto-histopathological studies around the world and do not attenuate the value of cervical cytology despite being unignorable, indicate the necessity of screening schemes involving the combined and effective use of different techniques such as Human papillomavirus (HPV) tests, repeated smear examinations, colposcopic examination, and biopsy in patients diagnosed by cervical cytology. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved. en_US
dc.identifier.doi 10.5505/ejm.2020.01886
dc.identifier.endpage 311 en_US
dc.identifier.issn 1301-0883
dc.identifier.issue 2 en_US
dc.identifier.scopus 2-s2.0-85083589977
dc.identifier.scopusquality Q4
dc.identifier.startpage 305 en_US
dc.identifier.trdizinid 363731
dc.identifier.uri https://doi.org/10.5505/ejm.2020.01886
dc.identifier.uri https://hdl.handle.net/20.500.14720/5477
dc.identifier.volume 25 en_US
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Yuzuncu Yil Universitesi Tip Fakultesi en_US
dc.relation.ispartof Eastern Journal of Medicine en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Cervical Smear en_US
dc.subject Correlation en_US
dc.subject Histology en_US
dc.title Correlation of Cervical Smear Cytology and Histopathology Findings From Van Yüzüncü Yıl University Dursun Odabaş Medical Center in Turkey en_US
dc.type Article en_US

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