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Serum Levels of Gastrin, and Insulin-Like Growth Factor (igf-1) in Patients With Gastro-Esophageal Cancer

dc.authorscopusid 6603791088
dc.authorscopusid 56069278500
dc.authorscopusid 6603300537
dc.authorscopusid 6701753460
dc.authorscopusid 7103280636
dc.authorscopusid 57196949201
dc.contributor.author Dülger, H.
dc.contributor.author Izmirli, M.
dc.contributor.author Şekeroǧlu, M.R.
dc.contributor.author Alici, S.
dc.contributor.author Özen, S.
dc.contributor.author Özcan, S.
dc.date.accessioned 2025-05-10T17:51:24Z
dc.date.available 2025-05-10T17:51:24Z
dc.date.issued 2007
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Dülger H., Yüzüncü Yil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Van, Turkey, Yüzüncü Yil Üniversitesi Tip Fakültesi, Biyokimya Anabilim Dali, 65300 Van, Turkey; Izmirli M., Yüzüncü Yil Üniversitesi, Tip Fakültesi, Radyasyon Onkolojisi Anabilim Dali, Van, Turkey; Şekeroǧlu M.R., Yüzüncü Yil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Van, Turkey; Alici S., Atatürk Eǧitim ve Araştirma Hastanesi Onkoloji Kliniǧi, Ankara, Turkey; Özen S., Yüzüncü Yil Üniversitesi, Tip Fakültesi, Patoloji Anabilim Dali, Van, Turkey; Özcan S., Yüzüncü Yil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Van, Turkey en_US
dc.description.abstract Gastrin and insulin-like growth factor (IGF-1) seem to play a significant role in cell proliferation of mammalian. In this study, we were aimed at investigating the serum levels of gastrin and IGF-1 in patients with gastric cancer and esophagus cancer. In 68 patients with gastric (40 patients) and esophagus (28 patients) cancer and 30 healthy adults were measured serum levels of gastrin, IGF-1, CEA, CA 19-9, CA 125 and growth hormone. All these parameters have been increased in both cancer groups (gastric and esophagus) than those of control group and these increase were significantly for serum levels of gastrin, CEA, CA 125 and growth hormone (p<0.05). It is concluded that in patients with gastric and esophagus cancer a significant increase of serum gastrin can be found and increased gastrin levels play a role in gastric and esophageal carcinogenesis. en_US
dc.identifier.endpage 142 en_US
dc.identifier.issn 1306-133X
dc.identifier.issue 3 en_US
dc.identifier.scopus 2-s2.0-35348884365
dc.identifier.scopusquality Q4
dc.identifier.startpage 138 en_US
dc.identifier.uri https://hdl.handle.net/20.500.14720/18111
dc.identifier.volume 17 en_US
dc.identifier.wosquality Q4
dc.language.iso tr en_US
dc.relation.ispartof UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Esophagus Cancer en_US
dc.subject Gastric Cancer en_US
dc.subject Gastrin en_US
dc.subject Igf-1 en_US
dc.title Serum Levels of Gastrin, and Insulin-Like Growth Factor (igf-1) in Patients With Gastro-Esophageal Cancer en_US
dc.type Article en_US

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