Functional Role of Crosslinking in Alginate Scaffold for Drug Delivery and Tissue Engineering: a Review
| dc.authorid | Zaldivar Silva, Dionisio/0000-0003-1266-0877 | |
| dc.authorid | Aguero Luztono, Lissette/0000-0003-0644-5011 | |
| dc.authorid | Gunduz, Oguzhan/0000-0002-9427-7574 | |
| dc.authorscopusid | 23026778200 | |
| dc.authorscopusid | 56403428200 | |
| dc.authorscopusid | 57216771506 | |
| dc.authorscopusid | 6602661346 | |
| dc.authorscopusid | 12797373800 | |
| dc.authorwosid | Alpdağtaş, Saadet/Jcf-1823-2023 | |
| dc.authorwosid | Gunduz, Oguzhan/Aaa-3212-2019 | |
| dc.authorwosid | Gunduz, Oguzhan/E-5292-2011 | |
| dc.contributor.author | Aguero, Lisette | |
| dc.contributor.author | Alpdagtas, Saadet | |
| dc.contributor.author | Ilhan, Elif | |
| dc.contributor.author | Zaldivar-Silva, Dionisio | |
| dc.contributor.author | Gunduz, Oguzhan | |
| dc.date.accessioned | 2025-05-10T17:14:57Z | |
| dc.date.available | 2025-05-10T17:14:57Z | |
| dc.date.issued | 2021 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Aguero, Lisette] Univ Havana, Dept Polymer Biomat, Ctr Biomat, Havana, Cuba; [Alpdagtas, Saadet; Ilhan, Elif; Gunduz, Oguzhan] Marmara Univ, Ctr Nanotechnol & Biomat Applicat & Res NBUAM, Istanbul, Turkey; [Alpdagtas, Saadet] Van Yuzuncu Yil Univ, Fac Sci, Dept Biol, Van, Turkey; [Ilhan, Elif] Marmara Univ, Dept Bioengn, Fac Engn, Istanbul, Turkey; [Zaldivar-Silva, Dionisio] Univ Havana, Havana, Cuba; [Gunduz, Oguzhan] Marmara Univ, Fac Technol, Dept Met & Mat Engn, Istanbul, Turkey | en_US |
| dc.description | Zaldivar Silva, Dionisio/0000-0003-1266-0877; Aguero Luztono, Lissette/0000-0003-0644-5011; Gunduz, Oguzhan/0000-0002-9427-7574 | en_US |
| dc.description.abstract | The actual tendency exhibits continuous increment to use alginate polysaccharides in drug delivery and tissue engineering fields due to its attractive properties. Alginate pH-sensitiveness and its fabrication techniques have been extensively reported in the literature. However, in this review, the essential role of crosslinking process in the scaffold design will be highlighted. We discuss the possibility to use a different type of crosslinking to create proper biomimetic alginate hydrogels, emphasizing the possibility to improve alginate mechanical properties through chemical modification by covalent crosslinking or ionic combination with other polymeric materials. At the same time, the relevance of the degradation process and biocompatibility in these applications is also detailed described. | en_US |
| dc.description.sponsorship | Marmara University Scientific Research Project Office [THD-2021-10238] | en_US |
| dc.description.sponsorship | This study is supported by Marmara University Scientific Research Project Office with project number: THD-2021-10238. | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded | |
| dc.identifier.doi | 10.1016/j.eurpolymj.2021.110807 | |
| dc.identifier.issn | 0014-3057 | |
| dc.identifier.issn | 1873-1945 | |
| dc.identifier.scopus | 2-s2.0-85116641347 | |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.uri | https://doi.org/10.1016/j.eurpolymj.2021.110807 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/8496 | |
| dc.identifier.volume | 160 | en_US |
| dc.identifier.wos | WOS:000708566500007 | |
| dc.identifier.wosquality | Q1 | |
| dc.language.iso | en | en_US |
| dc.publisher | Pergamon-elsevier Science Ltd | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Alginate | en_US |
| dc.subject | Crosslinking | en_US |
| dc.subject | Wound Healing | en_US |
| dc.subject | Drug Delivery | en_US |
| dc.subject | Tissue Engineering | en_US |
| dc.subject | Biocompatibility | en_US |
| dc.title | Functional Role of Crosslinking in Alginate Scaffold for Drug Delivery and Tissue Engineering: a Review | en_US |
| dc.type | Article | en_US |