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The Effect of Evening Primrose (Oenothera Biennis) on the Some Biochemical Parameters in Rats With Gentamicin Induced Nephrotoxicity

dc.contributor.author Mert, Nihat
dc.contributor.author Mert, Handan
dc.contributor.author İrak, Kıvanç
dc.contributor.author Medineli, Murat
dc.date.accessioned 2025-05-10T17:17:49Z
dc.date.available 2025-05-10T17:17:49Z
dc.date.issued 2021
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Van Yüzüncü Yil Üni̇versi̇tesi̇,Van Yüzüncü Yil Üni̇versi̇tesi̇,Si̇i̇rt Üni̇versi̇tesi̇,Van Yüzüncü Yil Üni̇versi̇tesi̇ en_US
dc.description.abstract In this study, it was aimed to investigate the effect of evening primrose oil (EPO) on somebiochemical parameters on nephrotoxicity induced by gentamicin (GM) in rats. The rats used in thestudy were randomly divided into 4 groups each consisting of 8 rats. The control group, EPO group,GM group and GM+ EPO group. The blood samples were taken 24 hours after the 8-day trial andkidneys were removed and saved for histopathological and PGE2 analysis. The serum creatinine,BUN, calcitriol, Ca, Na, Cl, K and P analyzes were performed via autoanalyser. PGE2 analysis wasperformed in kidney tissue via ELISA. Histopathological examination of the kidney tissues wasperformed. The levels of creatinine, BUN and Cl were significantly decreased and PGE2 and Caincreased in GM + EPO compared to GM group. The changes in the biochemical parametersexamined and the histopathological findings obtained, it can be said that the EPO weakens thenephrotoxic damage caused by GM and has the protective effects on the kidney. en_US
dc.identifier.endpage 1014 en_US
dc.identifier.issn 2148-127X
dc.identifier.issue 6 en_US
dc.identifier.scopusquality N/A
dc.identifier.startpage 1008 en_US
dc.identifier.trdizinid 454973
dc.identifier.uri https://search.trdizin.gov.tr/en/yayin/detay/454973/the-effect-of-evening-primrose-oenothera-biennis-on-the-some-biochemical-parameters-in-rats-with-gentamicin-induced-nephrotoxicity
dc.identifier.uri https://hdl.handle.net/20.500.14720/9415
dc.identifier.volume 9 en_US
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.relation.ispartof Türk Tarım - Gıda Bilim ve Teknoloji dergisi en_US
dc.relation.publicationcategory Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Tamamlayıcı Ve Entegre Tıp en_US
dc.subject Endokrinoloji Ve Metabolizma en_US
dc.subject Üroloji Ve Nefroloji en_US
dc.subject Veterinerlik en_US
dc.title The Effect of Evening Primrose (Oenothera Biennis) on the Some Biochemical Parameters in Rats With Gentamicin Induced Nephrotoxicity en_US
dc.type Article en_US

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