Cytotoxicity, Apoptotic, Antioxidant and Antimicrobial Activity of Dictyota Dichotoma (Hudson) Jv Lamouroux 1809 Collected From Antalya Coast, Turkiye
| dc.authorid | Cetin, Dogan/0000-0002-5733-4007 | |
| dc.authorscopusid | 59835383000 | |
| dc.authorscopusid | 57285719100 | |
| dc.authorscopusid | 57192910088 | |
| dc.authorscopusid | 57212383363 | |
| dc.authorscopusid | 56387553800 | |
| dc.authorscopusid | 57216928891 | |
| dc.authorscopusid | 6508159060 | |
| dc.authorwosid | Hafis Abdelsalam, Amine/Hjp-5798-2023 | |
| dc.authorwosid | Fi̇dan Babat, Ceylan/Hci-9656-2022 | |
| dc.authorwosid | Çetin, Doğan/Abq-1207-2022 | |
| dc.authorwosid | Kurt-Kizildogan, Aslihan/Jce-2182-2023 | |
| dc.authorwosid | Naz, Mehmet/Mck-3903-2025 | |
| dc.contributor.author | Arslan, Sevki | |
| dc.contributor.author | Abdelsalam, Amine Hafis | |
| dc.contributor.author | Kizildogan, Aslihan Kurt | |
| dc.contributor.author | Otur, Cigdem | |
| dc.contributor.author | Konus, Metin | |
| dc.contributor.author | Cetin, Dogan | |
| dc.contributor.author | Okudan, Emine Sukran | |
| dc.date.accessioned | 2025-06-01T20:06:57Z | |
| dc.date.available | 2025-06-01T20:06:57Z | |
| dc.date.issued | 2025 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Arslan, Sevki; Abdelsalam, Amine Hafis] Pamukkale Univ, Fac Sci, Dept Biol, TR-20160 Denizli, Turkiye; [Kizildogan, Aslihan Kurt; Otur, Cigdem] Ondokuz Mayis Univ, Dept Agr Biotechnol, TR-55139 Samsun, Turkiye; [Konus, Metin] Hitit Univ, Fac Arts & Sci, Dept Mol Biol & Genet, TR-19030 Corum, Turkiye; [Konus, Metin; Cetin, Dogan; Babat, Ceylan Fidan; Yilmaz, Can] Van Yuzuncu Yil Univ, Fac Sci, Dept Mol Biol & Genet, TR-65080 Van, Turkiye; [Oguztuzun, Serpil] Kirikkale Univ, Dept Biol, TR-71450 Kirikkale, Turkiye; [Sayin, Selin] Iskenderun Tech Univ, Fac Marine Sci & Technol, Dept Marine Technol, TR-31200 Hatay, Turkiye; [Naz, Mehmet] Iskenderun Tech Univ, Fac Marine Sci & Technol, Dept Aquaculture, TR-31200 Hatay, Turkiye; [Okudan, Emine Sukran] Akdeniz Univ, Fac Fisheries, TR-07058 Antalya, Turkiye | en_US |
| dc.description | Cetin, Dogan/0000-0002-5733-4007 | en_US |
| dc.description.abstract | Current study was purposed to reveal the cytotoxic, apoptotic, antimicrobial and antioxidant potentials of oil extracted from Dictyota dichotoma (Hudson) J.V. Lamouroux 1809 collected from Antalya coast of Turkiye. Dictyota dichotoma oil showed better cytotoxic activity towards two different adenocarcinoma cell lines (Caco-2 (8.83 mu g/mL) and LnCap (10.86 mu g/mL)) compared to HEK293 cells (non-cancerous). Annexin V/PI staining and qPCR studies revealed that oil caused induction of apoptosis. Dictyota dichotoma oil inhibited the growth of Aspergillus niger ATCC 16404 and Enterococcus faecalis ATCC 29212. Nevertheless, the lower antioxidant activity of Dictyota dichotoma oil was determined compared with trolox standard for both DPPH and ABTS assays (4.8 fold less). In conclusion, Dictyota dichotoma oil has a promising potential in medical usage. | en_US |
| dc.description.sponsorship | Scientific Research Projects Coordination Unit of Van Yuzuncu Yil University [FDK-2022-10354] | en_US |
| dc.description.sponsorship | This study was partially supported by the Scientific Research Projects Coordination Unit of Van Yuzuncu Yil University (Project no. FDK-2022-10354). | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded | |
| dc.identifier.doi | 10.1134/S1062359024608814 | |
| dc.identifier.issn | 1062-3590 | |
| dc.identifier.issn | 1608-3059 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.scopus | 2-s2.0-105004731294 | |
| dc.identifier.scopusquality | Q4 | |
| dc.identifier.uri | https://doi.org/10.1134/S1062359024608814 | |
| dc.identifier.volume | 52 | en_US |
| dc.identifier.wos | WOS:001485870100024 | |
| dc.identifier.wosquality | Q4 | |
| dc.language.iso | en | en_US |
| dc.publisher | Pleiades Publishing inc | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Dictyota Dichotoma | en_US |
| dc.subject | Cytotoxic Activity | en_US |
| dc.subject | Apoptosis Antimicrobial Potential | en_US |
| dc.subject | Antioxidant Activity | en_US |
| dc.subject | Gene Expression | en_US |
| dc.title | Cytotoxicity, Apoptotic, Antioxidant and Antimicrobial Activity of Dictyota Dichotoma (Hudson) Jv Lamouroux 1809 Collected From Antalya Coast, Turkiye | en_US |
| dc.type | Article | en_US |