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Malathion Resistance Mediated by Detoxification Enzymes in Sitophilus Zeamais (Motschulsky) (Coleoptera: Curculionidae)

dc.authorid Konus, Metin/0000-0002-9953-1375
dc.authorscopusid 56387553800
dc.contributor.author Konus, Metin
dc.date.accessioned 2025-05-10T16:57:01Z
dc.date.available 2025-05-10T16:57:01Z
dc.date.issued 2015
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Yuzuncu Yil Univ, Dept Mol Biol & Genet, Van, Turkey en_US
dc.description Konus, Metin/0000-0002-9953-1375 en_US
dc.description.abstract Sitophilus zeamais (Motschulsky) (Coleoptera: Curculionidae) is one of the economically important insect pests that infest stored products. In order to control this pest, chemical insecticides, such as malathion, have been widely used as grain protectants in many countries including Turkey. However, continuous application of insecticides at high doses has resulted in the development of resistance in this pest. Hence, this study aims to determine the toxicity of malathion insecticide at discriminating dose on S. zeamais populations and to analyse the role of detoxification enzyme systems in the development of resistance in S. zeamais populations in Turkey. Bioassay results showed that while S. zeamais Ankara population showed resistance to malathion insecticide, S. zeamais Samsun population did not show resistance to the insecticide. In addition, biochemical analysis indicated that CYP450-PNOD activities showed 2.0-fold increase in malathion resistant Ankara population. Although, EST-PNPA (1.3-fold) and GST-DCNB (1.5-fold) activities significantly increased in S. zeamais Samsun population, they did not show any significant changes in malathion resistant S. zeamais Ankara population. Consequently, it seems probable that cytochrome P450 monooxygenases play an active role in malathion resistance in Ankara population of S. zeamais. en_US
dc.description.sponsorship Yuzuncu Yil University (BAP) [2013-FEN-B058] en_US
dc.description.sponsorship I would like to thank to Yuzuncu Yil University (BAP Project No. 2013-FEN-B058) for financial support during this study. I also wish to thank Mrs. S.U. Karaagac for technical assistance for bioassays. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.endpage 2151 en_US
dc.identifier.issn 1018-4619
dc.identifier.issn 1610-2304
dc.identifier.issue 6A en_US
dc.identifier.scopus 2-s2.0-84978895990
dc.identifier.scopusquality N/A
dc.identifier.startpage 2146 en_US
dc.identifier.uri https://hdl.handle.net/20.500.14720/3903
dc.identifier.volume 24 en_US
dc.identifier.wos WOS:000363071600004
dc.identifier.wosquality N/A
dc.institutionauthor Konus, Metin
dc.language.iso en en_US
dc.publisher Parlar Scientific Publications (p S P) en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Sitophilus Zeamais en_US
dc.subject Malathion en_US
dc.subject Glutathione S-Transferases en_US
dc.subject Cytochrome P-450 Monooxygenases en_US
dc.subject Esterases en_US
dc.title Malathion Resistance Mediated by Detoxification Enzymes in Sitophilus Zeamais (Motschulsky) (Coleoptera: Curculionidae) en_US
dc.type Article en_US

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