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Synthesis and Antibacterial Activity of 4-Benzoyl Pyrazole-3 Acid and Derivatives

dc.authorscopusid 8242109800
dc.authorscopusid 6602615713
dc.authorscopusid 7103016054
dc.authorscopusid 16636647800
dc.contributor.author Akbas, E.
dc.contributor.author Berber, I.
dc.contributor.author Sener, A.
dc.contributor.author Hasanov, B.
dc.date.accessioned 2025-05-10T17:06:28Z
dc.date.available 2025-05-10T17:06:28Z
dc.date.issued 2005
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Akbas E., Faculty of Arts and Sciences, Chemistry Department, Organ. Chem. Div., Yuzuncu Yil Univ., 65080-Van, Turkey; Berber I., Faculty of Arts and Sciences, Biology Department, Molec. Biol. Div., Yuzuncu Yil Univ., 65080-Van, Turkey; Sener A., Faculty of Arts and Sciences, Chemistry Department, Organ. Chem. Div., Yuzuncu Yil Univ., 65080-Van, Turkey; Hasanov B., Faculty of Arts and Sciences, Chemistry Department, Organ. Chem. Div., Yuzuncu Yil Univ., 65080-Van, Turkey en_US
dc.description.abstract Some new 1H-pyrazole-3-carboxylic acid and pyridazinone derivatives were synthesized and evaluated for their antibacterial activities against Bacillus cereus ATCC 7064, Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 4230 and Pseudomonas putida using tube dilution method. The minimal inhibitory concentrations (MICs) experiments revealed that all chemical compounds showed inhibitor effects on the growth of the test microorganisms. Moreover, the results of this research showed that the compound named as 5c was the best compound in the series, exhibiting antibacterial activity against both Gram-positive and Gram-negative bacteria. © 2004 Published by Elsevier SAS. en_US
dc.identifier.doi 10.1016/j.farmac.2004.09.003
dc.identifier.endpage 26 en_US
dc.identifier.issn 0014-827X
dc.identifier.issue 1 en_US
dc.identifier.pmid 15652364
dc.identifier.scopus 2-s2.0-12344301275
dc.identifier.scopusquality N/A
dc.identifier.startpage 23 en_US
dc.identifier.uri https://doi.org/10.1016/j.farmac.2004.09.003
dc.identifier.uri https://hdl.handle.net/20.500.14720/6419
dc.identifier.volume 60 en_US
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.relation.ispartof Farmaco en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Antibacterial Activity en_US
dc.subject Pyrazole en_US
dc.subject Pyridazine en_US
dc.title Synthesis and Antibacterial Activity of 4-Benzoyl Pyrazole-3 Acid and Derivatives en_US
dc.type Article en_US

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