Electrochemical and Analytical Performance of Cathodically Pretreated Boron-Doped Diamond Electrode for the Determination of Oxazolidinone Antibiotic Linezolid in Cationic Surfactant Media
dc.authorid | Senturk, Zuhre/0000-0002-0356-9345 | |
dc.authorscopusid | 55807475500 | |
dc.authorscopusid | 7004177719 | |
dc.authorwosid | Senturk, Zuhre/Aas-5179-2020 | |
dc.authorwosid | Talay Pınar, Pınar/Jfj-2292-2023 | |
dc.contributor.author | Pinar, Pinar Talay | |
dc.contributor.author | Senturk, Zuhre | |
dc.date.accessioned | 2025-05-10T17:07:43Z | |
dc.date.available | 2025-05-10T17:07:43Z | |
dc.date.issued | 2020 | |
dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
dc.department-temp | [Pinar, Pinar Talay] Van Yuzuncu Yil Univ, Fac Pharm, Dept Analyt Chem, TR-65080 Van, Turkey; [Senturk, Zuhre] Van Yuzuncu Yil Univ, Fac Sci, Dept Analyt Chem, TR-65080 Van, Turkey | en_US |
dc.description | Senturk, Zuhre/0000-0002-0356-9345 | en_US |
dc.description.abstract | The electrochemical oxidation of an oxazolidinone class of antibiotic, Linezolid (LNZ) was studied in aqueous as well as aqueous/surfactant media on a commercially available boron-doped diamond (BDD) electrode pretreated cathodically. By using cyclic voltammetry, LNZ showed two couples of oxidation/reduction peak in aqueous solutions. The electrode process is pH-dependent and controlled by diffusion. The compound yielded two well-separated oxidation steps in acidic, neutral and alkaline media by employing square-wave voltammetry. The sensitivity of the voltammetric measurements was improved when the cationic surfactant, cetyltrimethylammonium bromide (CTAB) was present in the electrolyte solution at pH 4.0. In Britton-Robinson buffer containing 0.9 mM CTAB, the calibration curves were linear for both oxidation peaks (Ia and IIa) over concentration ranges of 0.25-6.41 mu g mL(-1) (0.74-19.27 mu M), with detection limits of 0.05 mu g mL(-1) (0.15 mu M) for Ia, and 0.12 mu g mL(-1) (0.34 mu M) for IIa. The practical applicability of developed methodology was tested in pharmaceutical formulations. | en_US |
dc.description.woscitationindex | Science Citation Index Expanded | |
dc.identifier.doi | 10.1016/j.jelechem.2020.114681 | |
dc.identifier.issn | 1572-6657 | |
dc.identifier.issn | 1873-2569 | |
dc.identifier.scopus | 2-s2.0-85091579162 | |
dc.identifier.scopusquality | Q2 | |
dc.identifier.uri | https://doi.org/10.1016/j.jelechem.2020.114681 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14720/6860 | |
dc.identifier.volume | 878 | en_US |
dc.identifier.wos | WOS:000593970100005 | |
dc.identifier.wosquality | Q1 | |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Science Sa | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Linezolid | en_US |
dc.subject | Boron-Doped Diamond Electrode | en_US |
dc.subject | Cathodic Pretreatment | en_US |
dc.subject | Square-Wave Voltammetry | en_US |
dc.subject | Cationic Surfactant | en_US |
dc.subject | Drug Analysis | en_US |
dc.title | Electrochemical and Analytical Performance of Cathodically Pretreated Boron-Doped Diamond Electrode for the Determination of Oxazolidinone Antibiotic Linezolid in Cationic Surfactant Media | en_US |
dc.type | Article | en_US |