Mortality and Severity Related Factors During the Admission: H1n1 Pneumonia

Abstract

In our country, fatal cases of H1N1 pneumonia were detected between 2015-2016 years. Our aim is to analyze the mortality and severity related factors, during admission of these patients. By conducting a retrospective analysis, 17 cases, confirmed to have H1N1 pneumonia, included in the study. Findings were compared in terms of ARDS and mortality. ICU and hospital mortality rates were 50% and 30%. The mean age of patients was 50 years. Serum LDH, CK, CK-MB, CRP AST, ALT levels, and the neutrophil-to-lymphocyte ratio (NLR) were found to be increased. In terms of co infections, there wasn't a significant difference between died and survived patients. The mortality rate was 50% in patients with ARDS. There was no relationship between hospital stay with mortality. The symptom of restlessness was related to mortality, and presence of ARDS (P<.05). In died and alive patients, the mean-ranks of PaO2, SpO2, and CURB-65 scores were 3.5, 9.7, 4.3, 10.96, 14.6, and 6.6, respectively (P<.05). PaO2 and SpO2 values were lower, and CURB-65 scores were higher in dead patients. SpO2 <79.5, PaO2 <62.5, and CURB-65 scores ≥2 were related to mortality (P<.05). However, CURB-65 <2 did not exclude severe pneumonia. There was no relationship between comorbid diseases and mortality. The main radiographic finding was bilateral infiltrates. This study suggests that PaO2, SpO2, and CURB scores of ≥2 and the presence of restlessness can be used to predict the severity and mortality in patients suspected to have H1N1 pneumonia, during admission. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.